scholarly journals Diffusion-weighted imaging of the breast: current status as an imaging biomarker and future role

BJR|Open ◽  
2019 ◽  
Vol 1 (1) ◽  
pp. 20180049 ◽  
Author(s):  
Julia Camps-Herrero
Keyword(s):  
Diffusion Weighted Imaging ◽  
Point Of View ◽  
Current Status ◽  
Imaging Biomarker ◽  
Proof Of Concept ◽  
Tissue Architecture ◽  
Intravenous Contrast ◽  
Diffusion Weighted ◽  
Contrast Enhanced ◽  
Proof Of Mechanism

Diffusion-weighted imaging (DWI) of the breast is a MRI sequence that shows several advantages when compared to the dynamic contrast-enhanced sequence: it does not need intravenous contrast, it is relatively quick and easy to implement (artifacts notwithstanding). In this review, the current applications of DWI for lesion characterization and prognosis as well as for response evaluation are analyzed from the point of view of the necessary steps to become a useful surrogate of underlying biological processes (tissue architecture and cellularity): from the proof of concept, to the proof of mechanism, the proof of principle and finally the proof of effectiveness. Future applications of DWI in screening, DWI modeling and radiomics are also discussed.

scholarly journals Understanding PI-QUAL for prostate MRI quality: a practical primer for radiologists

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Francesco Giganti ◽  
Alex Kirkham ◽  
Veeru Kasivisvanathan ◽  
Marianthi-Vasiliki Papoutsaki ◽  
Shonit Punwani ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Signal To Noise Ratio ◽  
High Signal ◽  
Diagnostic Quality ◽  
Prostate Mri ◽  
Prostate Imaging ◽  
Dynamic Contrast Enhanced ◽  
Diffusion Weighted ◽  
Contrast Enhanced

AbstractProstate magnetic resonance imaging (MRI) of high diagnostic quality is a key determinant for either detection or exclusion of prostate cancer. Adequate high spatial resolution on T2-weighted imaging, good diffusion-weighted imaging and dynamic contrast-enhanced sequences of high signal-to-noise ratio are the prerequisite for a high-quality MRI study of the prostate. The Prostate Imaging Quality (PI-QUAL) score was created to assess the diagnostic quality of a scan against a set of objective criteria as per Prostate Imaging-Reporting and Data System recommendations, together with criteria obtained from the image. The PI-QUAL score is a 1-to-5 scale where a score of 1 indicates that all MR sequences (T2-weighted imaging, diffusion-weighted imaging and dynamic contrast-enhanced sequences) are below the minimum standard of diagnostic quality, a score of 3 means that the scan is of sufficient diagnostic quality, and a score of 5 implies that all three sequences are of optimal diagnostic quality. The purpose of this educational review is to provide a practical guide to assess the quality of prostate MRI using PI-QUAL and to familiarise the radiologist and all those involved in prostate MRI with this scoring system. A variety of images are also presented to demonstrate the difference between suboptimal and good prostate MR scans.

scholarly journals Evaluation of diffusion-weighted imaging for the differential diagnosis of poorly contrast-enhanced and T2-prolonged bone masses: Initial experience

2006 ◽  
Vol 23 (3) ◽  
pp. 377-382 ◽  
Author(s):  
Yoshiko Hayashida ◽  
Toshinori Hirai ◽  
Toshitake Yakushiji ◽  
Kazuhiro Katahira ◽  
Osamu Shimomura ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Diffusion Weighted Imaging ◽  
Initial Experience ◽  
Diffusion Weighted ◽  
Contrast Enhanced

Multiparametric Approach with Dynamic Contrast-Enhanced Mri, Diffusion-Weighted Imaging and Mrs of The Breast in Assessment of Suspicious Breast Lesions

2020 ◽  
Vol 106 (1_suppl) ◽  
pp. 16-16
Author(s):  
SM Abd Elsalam ◽  
AH Said ◽  
MH Sarah
Keyword(s):  
Magnetic Resonance ◽  
Diffusion Weighted Imaging ◽  
Kinetic Curve ◽  
Resonance Spectroscopy ◽  
Breast Lesions ◽  
Adc Value ◽  
Dynamic Contrast Enhanced ◽  
Cancer Breast ◽  
Diffusion Weighted ◽  
Contrast Enhanced

Introduction: Breast cancer is the most invasive malignant tumour in females worldwide and is the second leading cause of cancer death in females after lung cancer. In Egypt, cancer breast is the first common site of tumours among females (32%) and the second common tumour site in both sexes. The aim of this study was to evaluate and compare the diagnostic performance of quantitative parameters derived from diffusion-weighted imaging (DWI), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and magnetic resonance spectroscopy (MRS) with ultrasound +/- conventional mammography in differentiating suspicious breast masses (BI-RADS III and IV) and to suggest the most accurate imaging combination for early diagnosis and treatment of cancer breast. Materials and Methods: The study included 40 patients with suspicious breast lesions detected by clinical examination, ultrasound+/- mammography . Dynamic MRI study was performed using 1.5T MRI. Lesions were analyzed regarding their morphology, kinetic curve pattern, ADC value and tCho peak measurement. The results of each MRI parameter were correlated to histo-pathology. Results: In this study sensitivity of sono-mammography was 70% and its specificity was 66.6%. According to using MRI sensitivity was 90% and specificity was 80% by using morphological and curve patterns. As regarding MRS sensitivity was 50% and specificity was 86.7%. Regarding sensitivity of ADC was 90%while its specificity was 93%. The cut off ADC value was 0.95 x 10−3 mm2/s. By using MRI with additive modalities (ADC and MRS) sensitivity was 100% and specificity was 93%. Conclusion: In comparison with MRI, sonomammography alone lack both sensitivity and specificity in detection of breast lesions in suspicious cases. MRI with additive modalities (ADC and MRS) is the best imaging modality in detection of malignant cases and exclusion of benign cases.

Sign in / Sign up

Export Citation Format

Share Document