Collaboration between an NHS University Teaching Hospital and independent hospital to maintain CT colonography service provision during the 2020 COVID-19 pandemic

Our trust performed CTCs at 93% of the capacity of the previous year, scanning 1265 patients in 2020, compared with 1348 in 2019. We describe the changes made to our service to achieve this, which included collaboration with the colorectal surgical team to prioritise existing CTC patients according to faecal-immunochemical tests and full blood count results, and the associated challenges which included image transfer delays and patient attendance for scans. Furthermore, the endoscopy and radiology services used the opportunity created by co-location at the same hospital site to provide a same day incomplete colonoscopy and staging service for optically confirmed cancers. Collaboration between the NHS and independent sector allowed us to achieve continuity of service provision during the height of the COVID-19 pandemic without substituting unprepared CT abdomen and pelvis instead of the more sensitive CTC.

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Ferritin and transferrin levels of the elderly population at Lagos State university teaching hospital, Ikeja, Lagos, Nigeria

International Journal of Scientific Reports ◽

10.18203/issn.2454-2156.intjscirep20214492 ◽

2021 ◽

Vol 7 (12) ◽

pp. 559

Author(s):

Abdulateef O. Kareem ◽

Akinsegun A. Akinbami ◽

Ebele I. Uche ◽

Aishatu M. Suleiman ◽

Rafah A. Bamiro ◽

...

Keyword(s):

Iron Deficiency ◽

Serum Ferritin ◽

Teaching Hospital ◽

Blood Count ◽

The Elderly ◽

University Teaching ◽

Full Blood Count ◽

State University ◽

Lagos State ◽

The Mean

Background: The elderly have limited regenerative abilities thus predisposing them to various diseases. Measuring both serum ferritin and transferrin serve as biomarkers of iron deficiency. This study, using enzyme-linked immunosorbent assay (ELISA) determined the serum levels of ferritin and transferrin in the elderly. Full blood count was also done and correlated with serum ferritin and transferrin levels of every participant.Methods: This was a cross-sectional study at the Geriatric Clinic of Lagos State University Teaching Hospital (LASUTH). Following receipt of written consents from ninety (90) elderly participants, venous samples were drawn for full blood count (FBC) and samples for serum ferritin and transferrin ELISA assay collected and stored at -40oC until the required sample size was obtained. Data were analyzed using SPSS version 23.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). The Pearson chi-square test was used for statistical analysis. P value was considered to be statistically significant when <0.05. Results: Participants consisted of 50 (55.6%) females and 40 (44.4%) males. The mean age of all participants was 71.31±7.38 years. The Majority, 90% (36 of 40) of the males had haemoglobin values lower than 13 gm/dl, while 66% (33 of 50) of females had haemoglobin values lower than 12 gm/dl. The mean ferritin concentration of all participants was 196.19 ±121.21ng/ml. The overall mean serum transferrin was 0.187±0.157 ng/ml with a minimum of 0.03 ng/ml and a maximum of 1.18 ng/ml.Conclusions: Anaemia in the elderly is very common using the World Health Organization (WHO) haemoglobin cut-off values, however, iron deficiency anaemia prevalence is low.

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Use of CT colonography (CTC) in selected patients referred on a suspected colorectal cancer pathway to a UK university teaching hospital - assessing the potential financial benefits of a straight to test model

10.26226/morressier.57c5383ed462b80296c9b6c4 ◽

2016 ◽

Author(s):

Thomas Garvey

Keyword(s):

Colorectal Cancer ◽

Teaching Hospital ◽

Ct Colonography ◽

University Teaching ◽

Test Model ◽

Financial Benefits

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Hematologic Abnormalities in Treatment-naïve HIV Patients

Infectious Diseases Research and Treatment ◽

10.4137/idrt.s6033 ◽

2010 ◽

Vol 3 ◽

pp. IDRT.S6033 ◽

Cited By ~ 2

Author(s):

Akinsegun Akinbami ◽

Olajumoke Oshinaike ◽

Titilope Adeyemo ◽

Adewunmi Adediran ◽

Owolabi Dosunmu ◽

...

Keyword(s):

Blood Count ◽

Demographic Data ◽

Cross Sectional Study ◽

Hiv Treatment ◽

University Teaching ◽

Full Blood Count ◽

Hiv Patients ◽

Cross Sectional ◽

Treatment Naïve ◽

Pre Treatment

Objectives Hematologic abnormalities, indicated by a deranged full blood count, are common manifestations and important prognostic tools for human immunodeficiency virus (HIV) infection and AIDS. This study aimed to determine the prevalence of cytopenia and its relationship to the degree of immunosupression in HIV treatment-naïve patients. Methods This was a cross-sectional study of treatment-naïve HIV-infected clients who enrolled at the HIV clinic of Lagos State University Teaching Hospital (LASUTH) between December 2009 and June 2010. Participants had samples taken for full blood count and CD4 counts, which are free routine pre-requisite and pre-treatment evaluations done for all registered HIV patients at LASUTH. They were asked to fill the structured questionnaires to obtain demographic data, with assistance if necessary. Results A total of 205 cases were reviewed: 24.2% had anemia (PCV < 30%), 26.8% had leucopenia (white blood cell <4,000/L) and 16.1% had thrombocytopenia (platelet count <150,000/L) at enrollment. The degree of cytopenia was directly related to the degree of immunosupression. Conclusion About one-fifth of HIV treatment-naïve patients were cytopenic at enrollment and the degree of cytopenia was directly related to the degree of immunosupression. It is necessary to investigate various causes of cytopenia in these patients so as to administer a specific intervention.

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A prospective pilot survey of the impact of general practitioner generated full blood count requests on clinical haematology workload: a London teaching hospital experience

Journal of Clinical Pathology ◽

10.1136/jclinpath-2011-200260 ◽

2011 ◽

Vol 65 (5) ◽

pp. 471-473

Author(s):

M S Islam ◽

B Sharma ◽

K Sullivan ◽

B J Hunt

Keyword(s):

General Practitioner ◽

Teaching Hospital ◽

Blood Count ◽

Full Blood Count ◽

Pilot Survey ◽

Hospital Experience ◽

The Impact

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Analysis of Full Blood Count and Bone Marrow Aspirations at Presentation in Children Diagnosed with Acute Leukaemias – A Single Centre Experience in Southern Nigeria

Journal of Cancer and Tumor International ◽

10.9734/jcti/2021/v11i230145 ◽

2021 ◽

pp. 1-8

Author(s):

G. K. Eke ◽

K. I. Korubo

Keyword(s):

Bone Marrow ◽

Acute Lymphoblastic Leukaemia ◽

Teaching Hospital ◽

Lymphoblastic Leukaemia ◽

Blood Count ◽

Paediatric Oncology ◽

Blood Film ◽

Full Blood Count ◽

Malignant Neoplasms ◽

Southern Nigeria

Introduction: Acute leukaemias are the most common malignant neoplasms in childhood, presenting with a variety of nonspecific symptoms. Though many of the recent more sophisticated methods of diagnosis have important prognostic implications, they are often not available in low- and middle-income countries. Objective: To review the full blood count and bone marrow aspirations at presentation in children diagnosed with acute leukaemias at a teaching hospital in southern Nigeria. Methodology: A retrospective survey of children with acute leukaemias admitted into the Paediatric Oncology unit of the University of Port Harcourt Teaching Hospital (UPTH), from January 2014 to December 2020. Their clinical profile, full blood count and bone marrow aspirations were analyzed using SPSS version 25.0 Results: Forty-three children aged 8 months to 17 years, with a median age of 9 years, were diagnosed with acute leukaemia within the period under review, 28 (65.1%) were males and 15 (34.9%) females, giving a M:F ratio of 1.9:1. Commonest clinical features at presentation were fever (n=28, 65.1%), pallor (n=18, 41.9%) and gum bleeding (n=16, 37.2%); while 38 (88.4%) of them presented with anaemia, 20 (46.5%) had leukocytosis and 36 (83.7%) had thrombocytopoenia with a median platelet count of 42x109/L and circulating blasts were present in the peripheral blood film of most of the patients. Acute lymphoblastic leukaemia (ALL) was the diagnosis in 30 (70%) children, and AML in 9 (21%). The bone marrow was hypercellular in 30 cases (69.8%) and erythropoiesis was depressed in 39 (90.7%) children. Conclusion: At the UPTH, children with acute leukaemias were mostly males. Fever, pallor and gum bleeding were the commonest symptoms with most of them having circulating blasts. Acute lymphoblastic leukaemia was the commonest type and bone marrow was mainly hypercellular with depressed erythropoiesis.

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Assessment of Hemoglobin Variants in Patients Receiving Health Care at the Ho Teaching Hospital: A Three-Year Retrospective Study

Advances in Hematology ◽

10.1155/2020/7369731 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Daniel Kpodji Awaitey ◽

Elliot Elikplim Akorsu ◽

Emmanuel Allote Allotey ◽

David Annor Kwasie ◽

Precious Kwablah Kwadzokpui ◽

...

Keyword(s):

Health Care ◽

Retrospective Study ◽

Sickle Cell Disease ◽

Sickle Cell ◽

Teaching Hospital ◽

Blood Count ◽

Full Blood Count ◽

Cell Disease ◽

Hemoglobin C ◽

Hemoglobin Variants

Background. It is estimated that one out of every three Ghanaians has hemoglobin genotype mutation. This change in genetic make-up may result in genotypes such as HbAS, HbSS, and HbSC. Many children in low- and middle-income countries die even before they are diagnosed with sickle cell disease (SCD). In Africa, there are limited data on the incidence and prevalence of SCD and the Volta region of Ghana is no exception. Aim. The aim of this study was to determine the prevalence of SCD and to assess the hemoglobin variants among patients attending Ho Teaching Hospital. Methods. A retrospective study design was used to extract information from the Hospital Administration and Management Systems (HAMS) on the hemoglobin electrophoresis results and corresponding full blood count results of the SCD and sickle cell anemia (SCA) patients as well as patients who were asked to do Hb electrophoresis irrespective of their sickling status. Data were collected for the period January 2016 to December 2018. Sickle cell disease status was determined using the Hb genotypes from the Hb electrophoresis results. The full blood count was used to categorize the severity of anemia based on the hemoglobin concentration in the SCA and SCD patients. Results. A total of 1,523 subjects were included in the study of which the prevalence for sickle cell disease was 16.7%. The SCD genotypes included HbS (6.2%), HbSC (7.9%), and HbSF (2.6%). Hemoglobin C disease (HbCC) constituted 0.3% out of the total prevalence of SCD. The prevalence of anemia was 99.2%, with the severest form in HbS. Also, majority of the SCD patients had severe anemia. Difference in the severity of anemia was found to be significant among both male (P=0.006) and female (P=0.004) participants with SCD. Conclusion. Patients receiving health care at the Ho Teaching Hospital had different hemoglobin variants with HbAS recording the highest prevalence. The high incidence of hemoglobin AS implies the possibility of having an increased population of individuals with sickle cell disease in future if measures are not put in place to improve screening, counseling, and education of the public about the health threat SCD poses.

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