scholarly journals Associations of multidimensional temperament and character profiles with cognition and sensorimotor gating in individuals at risk for schizophrenia-spectrum disorders: preliminary findings

Author(s):  
Chrysoula Zourakaki ◽  
Penny Karamaouna ◽  
Leda Karagiannopoulou ◽  
Stella Giakoumaki

Cloninger’s biopsychological model for personality distinguishes between Temperament [Novelty Seeking, Harm Avoidance (HA), Reward Dependence (RD), Persistence (PS)], and Character [Self-Directedness (SD), Cooperativeness (CO), Self-Transcendence (ST)] traits. Cloninger has also described three sets of complex interactions among these traits, which can be summarized as a linked network of three cubes. Within each cube, the different combinations of the sub-dimensions formulate multidimensional profiles that describe personality more accurately compared with their individual constituents. The aim of the present study was to examine differences of these multidimensional profiles in cognitive functions and Prepulse Inhibition (PPI) in unaffected relatives of schizophrenia-spectrum patients and control individuals. We assessed 114 unaffected relatives of schizophrenia-spectrum patients and 122 controls for Temperament/Character traits, a wide range of cognitive functions, and PPI of the acoustic startle reflex. The relatives had higher Ηarm Avoidance and Self-Transcendence along with lower Reward Dependence, Persistence, Self-Directedness and Cooperativeness scores as well as lower PPI and poorer cognition compared with controls. We also found a) unequal distribution of relatives and controls in several “disadvantageous” profiles associated with the schizophrenia-spectrum, b) the Schizotypal/Disorganized, Apathetic and Fragile profiles had poorer emotional decision making and attention switching, respectively, compared with their “advantageous” counterparts and c) the Adventurous, Independent, Bossy and Resilient profiles had higher PPI compared with their counterparts. These findings further highlight the significance of personality determinants of cognitive processes and have potential implications in early intervention programs in the schizophrenia-spectrum.

2020 ◽  
pp. 1-10
Author(s):  
José Manuel Rodríguez-Sánchez ◽  
Esther Setién-Suero ◽  
Paula Suárez-Pinilla ◽  
Jaqueline Mayoral Van Son ◽  
Javier Vázquez-Bourgon ◽  
...  

Abstract Background A large body of research states that cognitive impairment in schizophrenia is static. Nevertheless, most previous studies lack a control group or have small study samples or short follow-up periods. Method We aimed to address these limitations by studying a large epidemiological cohort of patients with first-episode schizophrenia spectrum disorders and a comparable control sample for a 10-year period. Results Our results support the generalized stability of cognitive functions in schizophrenia spectrum disorders considering the entire group. However, the existence of a subgroup of patients characterized by deteriorating cognition and worse long-term clinical outcomes must be noted. Nevertheless, it was not possible to identify concomitant factors or predictors of deterioration (all Ps > 0.05). Conclusions Cognitive functions in schizophrenia spectrum disorder are stable; however, a subgroup of subjects that deteriorate can be characterized.


2016 ◽  
Vol 224 (3) ◽  
pp. 204-215 ◽  
Author(s):  
Ljiljana B. Lazarević ◽  
Michael Bošnjak ◽  
Goran Knežević ◽  
Boban Petrović ◽  
Danka Purić ◽  
...  

Abstract. This meta-analytic study investigates the relations between Disintegration-like phenomena (i.e., various aspects of symptomatology with the prefix “schizo-,” both at the clinical and the subclinical level) and the traits of the Psychobiological Model of Personality (PBMP). The empirically based benchmark for assuming the distinctness of the trait Disintegration was .30. The sample included 26 manuscripts with 30 studies and 424 effect sizes. By computing inverse sampling variance weighted mean correlation coefficients under a random-effects assumption, the following associations were found between Disintegration and Harm Avoidance, Novelty Seeking, Reward Dependence, Persistence, Self-Directedness, Cooperativeness, and Self-Transcendence: .23, .04, −.15, −.02, −.23, −.16, and .17, respectively. Two variables were found to moderate the Disintegration-Self-Transcendence correlation. Despite the theoretical expectation and some empirical evidence that Self-Transcendence (and other character traits) should capture variations in Disintegration-like phenomena, our results suggest that schizo-type phenomena are not adequately covered by the PBMP.


2005 ◽  
Vol 77 (2-3) ◽  
pp. 279-288 ◽  
Author(s):  
José Manuel Rodríguez-Sánchez ◽  
Benedicto Crespo-Facorro ◽  
Rocío Perez Iglesias ◽  
César González-Blanch Bosch ◽  
Mario Álvarez ◽  
...  

Author(s):  
Sezen Güngör ◽  
Engin Demirel ◽  
Nihan Tomris Küçün

Over the past decades, Cloninger et al. have developed a biosocial model of personality based on four temperaments and three characteristics. This multidimensional psychobiological model of personality presents in the temperament and character inventory – revised (TCI-R) form. Temperament subscales are novelty seeking (NS), harm avoidance (HA), reward dependence (RD), and persistence (P), and character subscales are self-directedness (SD), cooperativeness (CO), and self-transcendence (ST). The study has been used in different disciplines of science, especially in psychology. Behavioral finance is one of these disciplines of science. TCI is frequently used, especially for investor biases. In this chapter, TCI is used to examine the relationship between investor biases and personality. The first three chapters are about personality. Personality, personality approaches, and personality measurement methods examined in these sections. In the fourth part, emotional biases in financial investment decisions searched. In the fifth part, literature studies showing the relationship between personality and financial decisions included. Finally, a field survey is conducted, and findings are revealed.


1996 ◽  
Vol 8 (1) ◽  
pp. 247-272 ◽  
Author(s):  
N. M. Švrakić ◽  
Dragan M. Švrakić ◽  
C. Robert Cloninger

AbstractA general theory of personality and its development is described in terms of four quantitative dimensions of temperament and three quantitative dimensions of character. The four temperament dimensions (harm avoidance, novelty seeking, reward dependence, and persistence) are moderately heritable, moderately stable throughout life, and invariant despite sociocultural influences. The three character dimensions (self-directedness, cooperativeness, and self-transcendence) mature in a stepwise manner from early childhood throughout adulthood. Transitions between levels of maturity are nonlinear functions of temperament, specific genetic influences, social learning, and random life events. Personality development is quantitatively formulated in terms of nonlinear dynamics of a complex adaptive system. The psychosocial interpretation of personality as a fitness-optimizing process is described and illustrated in terms of available data about the development of different personality configurations. Several quantitative predictions of this theory of personality development are tested, including the sequence of emergence of the different character dimensions, individual differences in the development of stable temperament configurations, and the effects of sociocultural influences. The theoretical predictions agree with available empirical data and suggest many hypotheses for future developmental research, including etiological, dynamic, and therapeutic studies.


2004 ◽  
Vol 185 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Laura T. Niemi ◽  
Jaana M. Suvisaari ◽  
Jari K. Haukka ◽  
Gunnel Wrede ◽  
Jouko K. Lönnqvist

BackgroundThe Helsinki High-Risk Study follows up all women born between 1916 and 1948 and treated for schizophrenia-spectrum disorders in psychiatric hospitals in Helsinki, their offspring born between 1960 and 1964, and controls.AimsTo determine the cumulative incidence of adulthood Axis I disorders among offspring.MethodUsing all hospital and out-patient treatment records we rediagnosed parents and offspring according to DSM– IV-TR criteria. Offspring were grouped by mother's diagnosis (schizophrenia n = 104, schizoaffective disorder n=20, other schizophrenia-spectrum disorder n=30, and affective disorder n=25) and compared with a control group (n = 176). The cumulative incidences of Axis I disorders among offspring were calculated.ResultsThe cumulative incidences of any psychotic disorder were 13.5%, 10.0%, 10.0%, 4.0% and 1.1% among offspring of mothers with schizophrenia, schizo-affective disorder, other schizophrenia-spectrum disorders, affective disorders and controls, respectively. The corresponding figures for schizophrenia were 6.7%, 5.0%, 6.7%, 0% and 0.6%, and for any mental disorder 23.1%, 20.0%, 20.0%, 12.0% and 6.9%.ConclusionsOffspring of mothers with a psychotic disorder have heightened risk of developing a wide range of severe mental disorders.


2022 ◽  
Vol 50 (1) ◽  
pp. 030006052110707
Author(s):  
Saeid Komasi ◽  
Farzin Rezaei ◽  
Azad Hemmati ◽  
Khaled Rahmani ◽  
Federico Amianto ◽  
...  

Objective To explore the relationship between temperament and character traits in Cloninger’s psychobiological theory and mental disorders. Methods: A systematic literature search was conducted of five international databases for all articles published in English between January 1990 and April 2019 (PROSPERO-CRD42019133214). Owing to heterogeneity, pooled estimates of correlations for personality disorders and standardized mean differences for case–control studies related to other mental disorders were calculated using the random-effects method. Results The pooled effect sizes obtained from 149 studies showed that high harm avoidance (related to 22/24 diagnostic categories), low self-directedness (21/23), low cooperativeness (17/23), high self-transcendence (14/23), low reward dependence (11/24), high novelty-seeking (10/24), low novelty-seeking (7/24), high persistence (2/23), low persistence (2/23) and high reward dependence (2/24) were related to psychopathology. Conclusions All traits provided unique psychobiological tools for differential diagnosis of mental disorders. However, high harm avoidance and low self-directedness played a canonical role in psychopathology. Despite the study limitations, additional studies are warranted to evaluate the differential diagnoses suggested by the present model.


2016 ◽  
Vol 37 (3) ◽  
pp. 168-180 ◽  
Author(s):  
Benjamin Calvet ◽  
Marion Péricaud ◽  
Matthieu Parneix ◽  
Adrien Jouette ◽  
Magali Bricaud ◽  
...  

Abstract. The authors examined age and sex trends on the seven dimensions and 25 facets assessed by the Temperament and Character Inventory (TCI) collected between 2006 and 2014. This cross-sectional study sought to better understand personality differences according to age and sex cohorts in a French nonclinical community sample (1,181 participants). Our results show significant differences in age groups in Novelty Seeking, Reward Dependence, Harm Avoidance, and Self-Transcendence. Women scored higher than men in Harm Avoidance, Reward Dependence, and Cooperativeness. Men between 18 and 29 years old reported higher Novelty Seeking whereas older women had higher Harm Avoidance. Among all the dimensions of the TCI, only Self-Directedness presents a consistent Gender × Age interaction. Our study confirmed that there were personality-specific features in men and women. In addition, there were personality changes with age in both temperament and character dimensions. Our research highlighted the need to take into account both age and gender of subjects in the future analyses and interpretations of findings from the temperament and character inventories.


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