scholarly journals Case Report: A giant myopericytoma involving the occipital region of the scalp - a rare entity

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2905 ◽  
Author(s):  
Sunil Munakomi ◽  
Pramod Chaudhary
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Histological Examination ◽  
Rare Case ◽  
Smooth Muscle Actin ◽  
Positive Staining ◽  
Occipital Region ◽  
Rare Entity ◽  
Muscle Actin ◽  
Complete Excision

Herein we report a rare case of a giant myopericytoma presenting in a 16-year-old girl as a slowly progressive swelling involving the scalp in the occipital region. It was managed by complete excision. Histological examination of the lesion revealed  spindle-shaped cells forming characteristic rosettes around the blood vessels, and positive staining with smooth muscle actin.

MESENCHYMAL TUMOR LEIOMYOSARCOMA OF PROSTATE, A RARE CASE REPORT

2021 ◽  
pp. 21-22
Author(s):  
Ekta Rani ◽  
Sarita Nibhoria ◽  
Bikramjit Singh ◽  
Aradhana Singh Hada ◽  
Parminderjeet Singh Sandhu
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Tumor Cells ◽  
Poor Prognosis ◽  
Rare Case ◽  
Smooth Muscle Actin ◽  
Mesenchymal Tumor ◽  
Muscle Actin ◽  
Rare Case Report ◽  
Rare Malignancy

Primary prostate sarcoma is a rare malignancy of the prostate with poor prognosis. It accounts for <1% of the tumors of the prostate. Leiomyosarcoma is the most common sarcoma involving the prostate in adults affecting men between the ages of 40 and 78 years. Tumor cells commonly express vimentin, smooth muscle actin and desmin, and up to 25% express cytokeratins.

scholarly journals Uterine Leiomyosarcoma Associated with Cystic Endometrial Polyps, Chondriod Metaplasia and Uterine Horn Intussusception in a Greater Cane Rat (Thryonomys swinderianus)

2020 ◽  
Vol 43 (2) ◽  
pp. 197-204
Author(s):  
Olusola Lawrence Ajayi ◽  
Moshood Olajire Olaniyi ◽  
Olugbenga Olayinka Alaka ◽  
Richard Edem Antia ◽  
Temitope Morenikeji Oladipo
Keyword(s):  
Smooth Muscle ◽  
Rare Case ◽  
Smooth Muscle Actin ◽  
Uterine Horn ◽  
Uterine Leiomyosarcoma ◽  
Muscle Actin ◽  
Immunohistochemical Examination ◽  
Endometrial Polyps ◽  
Greater Cane Rat ◽  
Positive Immunoreactivity

AbstractA rare case of uterine leiomyosarcoma associated with chondriod metaplasia, cystic endometrial polyps and uterine horn intussusception in a greater cane rat was macroscopically, histopathologically, immuno-histochemically and ultrastructurally evaluated. The histopathological findings for this tumour were similar to those for leiomyosarcomas described in other species. Immunohistochemical examination demonstrated positive immunoreactivity of neoplastic cells with α-smooth muscle actin, desmin and vimentin. Ultrastructurally, nuclear and cytoplasmic features were consistent with leiomyosarcoma. These results revealed the tumour to be of smooth muscle origin. To our knowledge, this is the first reported case of uterine leiomyosarcoma associated with cystic endometrial polyps, chondriod metaplasia and uterine horn intussusception in a greater cane rat.

scholarly journals Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review

2021 ◽  
pp. 101-106
Author(s):  
Akira Ishikawa ◽  
Kazuya Kuraoka ◽  
Junichi Zaitsu ◽  
Akihisa Saito ◽  
Atsushi Kamigaichi ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Literature Review ◽  
Tumor Cells ◽  
Growth Pattern ◽  
Mediastinal Mass ◽  
Smooth Muscle Actin ◽  
Anterior Mediastinum ◽  
Anterior Mediastinal Mass ◽  
Muscle Actin

Primary mediastinal sarcomas are extremely rare. Additionally, mediastinal leiomyosarcomas account for approximately 9% of mediastinal sarcoma cases. Until date, only few cases of anterior mediastinal leiomyosarcomas have been reported. Herein, we report a case of an 85-year-old female with an anterior mediastinal mass of 15 mm. Histological examination revealed spindle tumor cells showing a fascicular growth pattern. Immunohistochemically, the tumor cells were focal positive for desmin, calponin, and α-smooth muscle actin. The pathological diagnosis was leiomyosarcoma. In conclusion, we encountered a case of a very rare leiomyosarcoma that occurred in the anterior mediastinum, and our report may contribute to the understanding of this disease.

scholarly journals Inflammatory fibroid polyp: an immunohistochemical study

2004 ◽  
Vol 41 (2) ◽  
pp. 104-107 ◽  
Author(s):  
Gilda da Cunha Santos ◽  
Venâncio A.F. Alves ◽  
Alda Wakamatsu ◽  
Sérgio Zucoloto
Keyword(s):  
Smooth Muscle ◽  
Factor Viii ◽  
Immunohistochemical Study ◽  
Smooth Muscle Actin ◽  
Positive Staining ◽  
Muscle Actin ◽  
Inflammatory Fibroid Polyp ◽  
Spindle Cells ◽  
S 100 ◽  
Fibroid Polyp

BACKGROUND: Inflammatory fibroid polyp is a localized lesion, which arises in the submucosa of the gastrointestinal tract, most often in the stomach.Although it is generally believed to represent a reactive, nonneoplastic condition, its histogenesis remains controversial. AIM: To study inflammatory fibroid polyp by immunohistochemistry in an attempt to further clarify their histogenesis. MATERIAL AND METHODS: Nine cases were studied by immunohistochemistry using a panel of antibodies against smooth-muscle actin, vimentin, S-100 protein, factor VIII- R.Ag and macrophage (HAM-56). RESULTS: There was a strong diffuse positive staining pattern in the spindle cells with vimentin antibody. A patchy staining for smooth-muscle actin was observed in these cells. Immunophenotyping revealed a heterogeneous reaction with HAM-56. In edematous areas, HAM-56-positive cells show voluminous cytoplasm and reniform nuclei. In cell-rich areas, the HAM-56-positive cells had fusiform cytoplasm. Stains for S-100 and factor VIII RAg were negative in the proliferating elements. CONCLUSIONS: The present immunohistochemical study refutes the suggested neural or vascular nature of the lesion. The strong positivity for vimentin in all cases suggests a major component of spindle cells best recognizable as fibroblasts. These results would favor the existence of a span of morphological and immunohistochemical patterns possibly indicating evolutive phases of an inflammatory reaction.

scholarly journals Cutaneous myofibroblastic fibrosarcoma in a margay (Leopardus wiedii): a case report

2020 ◽  
Vol 13 (3) ◽  
pp. 597-601
Author(s):  
Raúl Bermúdez-Salas ◽  
Natalia Campos ◽  
Daniel Barrantes ◽  
Randall Arguedas ◽  
Alejandro Alfaro-Alarcón
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Actin ◽  
Histopathological Analysis ◽  
Muscle Actin ◽  
First Report ◽  
Mesenchymal Neoplasm

A routine check-up was performed on a captive 14-year-old female margay (Leopardus wiedii), a cutaneous mass was detected on the ventral thorax. The mass was surgically removed and sent for histopathological analysis. Histologically, the mass was a poorly-demarcated, highly cellular, infiltrative and unencapsulated mesenchymal neoplasm. Immunohistochemical labeling for smooth muscle actin and vimentin were positive, while desmin and cytokeratin were negative which is consistent with a myofibroblastic fibrosarcoma. This type of tumor has been diagnosed in wild felines, however this seems to be the first report of its occurrence in this L. wiedii. Wildlife oncology studies should be performed to promote our understanding of cancer in a species.

scholarly journals Case Report: Sciatic nerve schwannoma - a rare cause of sciatica

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 267 ◽  
Author(s):  
Sunil Munakomi ◽  
Pratyush Shrestha
Keyword(s):  
Case Report ◽  
Lumbar Spine ◽  
Sciatic Nerve ◽  
Complete Resolution ◽  
Rare Case ◽  
Rare Entity ◽  
Complete Excision ◽  
Prolapsed Disc ◽  
Straight Leg Raise ◽  
Possible Cause

Herein we report a rare case of a sciatic nerve schwannoma causing sciatica in a 69-year-old female. Sciatic nerve schwannoma is a rare entity. It should always be considered as a possible cause of sciatica in patients that present with symptoms of sciatica with no prolapsed disc in the lumbar spine and a negative crossed straight leg raise test. Timely diagnosis and complete excision of the lesion leads to complete resolution of the symptoms of such patients.

Renal Myopericytoma: Case Report and Review of Literature

2012 ◽  
Vol 136 (5) ◽  
pp. 563-566 ◽  
Author(s):  
Sadhna Dhingra ◽  
Alberto Ayala ◽  
Hong Chai ◽  
Vanessa Moreno ◽  
Bihong Zhao
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Renal Mass ◽  
Smooth Muscle Actin ◽  
Muscle Actin ◽  
Review Of Literature ◽  
Computed Tomography Scan ◽  
Muscle Myosin ◽  
Cd34 Expression ◽  
Tomography Scan

Myopericytoma arising in the visceral organs is rare and only 1 case of renal myopericytoma has been reported in the literature to date. We report the second case of myopericytoma arising in the kidney in a 40-year-old Hispanic woman who presented with pain on the left side of the abdomen and frequent urination. Abdominal computed tomography scan showed an exophytic left-sided renal mass. Partial nephrectomy was performed. The patient remains free of disease at 24 months after diagnosis. Our case is histologically distinct from the previously described case as it lacks the “hemangiopericytic/glomangiopericytoma” pattern. The tumor in our case showed the characteristic pattern of myopericytoma and an additional glomus tumorlike pattern. The tumor cells showed diffuse reactivity for vimentin, smooth muscle actin, smooth muscle myosin heavy chain, and muscle-specific actin in both morphologic patterns and strong diffuse CD34 expression in glomus tumorlike focus. This case report adds to the morphologic heterogeneity of myopericytomas.

Prostatic Rhabdomyoma in a Toddler: A Case Report With Molecular Characterization

2021 ◽  
pp. 109352662110469
Author(s):  
Paola X. De la Iglesia Niveyro ◽  
J. Pandolfi ◽  
F. Jauk ◽  
T. Kreindel ◽  
P. Lobos
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Next Generation Sequencing ◽  
Smooth Muscle Actin ◽  
Muscle Actin ◽  
Ultrasound Evaluation ◽  
Microscopic Evaluation ◽  
Generation Sequencing

We present a 29-month-old male patient in follow-up due to pyelocaliceal dilation with a prostatic nodule incidentally found during ultrasound evaluation. Cysto video endoscopy was performed and a prostate biopsy, obtained. Microscopic evaluation showed a haphazardly distributed population of muscular cells with cross striations without evidence of mitosis or necrosis. Immunohistochemistry was positive for myogenin and desmin and negative for smooth muscle actin. Next generation sequencing was performed without finding any pathogenic variant or fusion in the tumor RNA. The patient received no further treatment, remained asymptomatic and continues in follow up, 3 years after initial diagnosis. We report a case of prostate rhabdomyoma in a toddler, an exceptional location that raises concern about differential diagnosis with its malignant counterpart, rhabdomyosarcoma, especially at this age.

Sign in / Sign up

Export Citation Format

Share Document