scholarly journals Case Report: Synchronous primary malignancy including the breast and endometrium

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1502
Author(s):  
Elham Sadat Banimostafavi ◽  
Sepideh Tayebi ◽  
Maryam Tayebi ◽  
Fatemeh Montazer

Breast and endometrial cancer are the most common types of female cancers, but the incidence of both of these malignancies in a single patient is a rare event. Multiple primary malignancy has been increasingly reported over the past decade, and double primary cancer is considered as the most common type.  In this study, we present a 53-year-old woman with synchronous primary malignancy of breast and endometrium. This patient had a history of breast and endometrial cancer in her family. Mammography and chest CT of the patient revealed a mass in the right breast and left supraclavicular region. However, the patient did not want to initiate treatment. Subsequently, the patient returned with a chief complaint of persistent abnormal vaginal bleeding. Abdominopelvic CT scan of the patient revealed a huge soft tissue mass in the pelvic cavity. She underwent hysterectomy, and pathology revealed endometrioid carcinoma, which had invaded the full thickness of uterine wall. Since this type of malignancy is rare and several risk factors are associated with it, it is worth being considered by clinicians when making decisions about screening or strategy for prevention.

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1502 ◽  
Author(s):  
Elham Sadat Banimostafavi ◽  
Sepideh Tayebi ◽  
Maryam Tayebi

Breast and endometrial cancer are the most common types of female cancers, but the incidence of both of these malignancies in a single patient is a rare event. Multiple primary malignancy has been increasingly reported over the past decade, and double primary cancer is considered as the most common type.  In this study, we present a 53-year-old woman with synchronous primary malignancy of breast and endometrium. This patient had a history of breast and endometrial cancer in her family. Mammography and chest CT of the patient revealed a mass in the right breast and left supraclavicular region. However, the patient did not want to initiate treatment. Subsequently, the patient returned with a chief complaint of persistent abnormal vaginal bleeding. Abdominopelvic CT scan of the patient revealed a huge soft tissue mass in the pelvic cavity. She underwent hysterectomy, and pathology revealed endometrioid carcinoma, which had invaded the full thickness of uterine wall. Since this type of malignancy is rare and several risk factors are associated with it, it is worth being considered by clinicians when making decisions about screening or strategy for prevention.


F1000Research ◽  
2018 ◽  
Vol 6 ◽  
pp. 1502
Author(s):  
Elham Sadat Banimostafavi ◽  
Sepideh Tayebi ◽  
Maryam Tayebi ◽  
Fatemeh Montazer

Breast and endometrial cancer are the most common types of female cancers, but the incidence of both of these malignancies in a single patient is a rare event. Multiple primary malignancy has been increasingly reported over the past decade, and double primary cancer is considered as the most common type.  In this study, we present a 53-year-old woman with synchronous primary malignancy of breast and endometrium. This patient had a history of breast and endometrial cancer in her family. Mammography and chest CT of the patient revealed a mass in the right breast and left supraclavicular region. However, the patient did not want to initiate treatment. Subsequently, the patient returned with a chief complaint of persistent abnormal vaginal bleeding. Abdominopelvic CT scan of the patient revealed a huge soft tissue mass in the pelvic cavity. She underwent hysterectomy, and pathology revealed endometrioid carcinoma, which had invaded the full thickness of uterine wall. Since this type of malignancy is rare and several risk factors are associated with it, it is worth being considered by clinicians when making decisions about screening or strategy for prevention.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
Al-shaimaa G Soliman ◽  
S A Abdelrahman ◽  
A A Darweesh ◽  
W B Gerges ◽  
H S Tantawy

Abstract Background Brest feeding is an important process that’s not only important for baby nutrition but also it strengthens the relation between the mother and her baby. Female breast undergoes multiple physiological changes during pregnancy and lactation.if the female not well educated about them and how to deal with them it will be a source of great horror to the female and her family as they consider any pain or unknown change in the breast as cancer until proved otherwise. Objective To assess breast care during pregnancy and its preparation for lactation and the value of this care in preventing breast infection. Patients and Methods This is a prospective study included 85 female patients coming to breast clinic and obstetric clinic of El Demerdash Hospital from September 2017 to August 2018. 40 of them presented during the third trimester of their pregnancy and the remaining 45 presented during lactation period. Sixty –three of them were multipara, the others were primigravida. Thirty of them gave a history of problems with previous lactation. Results In our research, females who came and were followed during pregnancy were educated about the importance of breast feeding to the baby and to the mother during their visits to the obstetric clinic. They were taught how to take care of their breast preparing it for safe and comfortable nursing. 35% of them were previously suffered from breast engorgement in previous lactation but when they followed our instructions about 27% of them developed breast engorgement which relieved rapidly without progressing to further complications. Also 5% previously developed breast abscess which was avoided in current study. We had also two of our participants that had retracted nipple one of them had previous experience of lactation that stopped shortly after birth but when we reassure her and learn her how to prepare her nipples by gentle massage, lubricants and use of plastic shells after delivery she could overcome her problem and continue breast feeding. Females who came during lactation were not prepared properly during pregnancy and 44% of them suffered from breast engorgement which was relieved with proper management but one of them developed breast abscess. Conclusion Every female have to learn about the right position of nursing and how to make proper care of her breasts and when she has to seek medical advice. This will help her to adapt the act of nursing and overcome any annoying problem that she may face during this period.


2007 ◽  
Vol 35 (5) ◽  
pp. 724-730 ◽  
Author(s):  
EH Kayias ◽  
GI Drosos ◽  
KI Kazakos ◽  
C Iatrou ◽  
KS Blatsoukas ◽  
...  

We report the rare case of a histologically proven mixed-type intramuscular haemangioma, adjacent to the periosteum of the radius, that caused a periosteal reaction. We also carried out a review of the literature relevant to this case. A 28-year-old male professional drummer presented with an 8-month history of pain and swelling of the dorsal aspect of the right radius. Diagnosis was established on the basis of plain radiographs and magnetic resonance imaging, and was confirmed by histology. The lesion was treated solely by resection of the soft-tissue mass. The patient remained asymptomatic 4 years post-operatively, with no radiographic signs of recurrence. From a review of the literature, it is evident that the terminology for haemangiomas causing regional bone changes is unclear. A new classification of the intramuscular haemangiomas is proposed in order to distinguish between lesions that, according to current knowledge, exhibit radiological and clinical areas of overlap.


2000 ◽  
Vol 118 (4) ◽  
pp. 118-120 ◽  
Author(s):  
Márcio Abrahão ◽  
Ana Paula Vieira Gonçalves ◽  
Roberto Yamashita ◽  
Rogério Aparecido Dedivitis ◽  
Rodrigo Oliveira Santos ◽  
...  

CONTEXT: Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year, with the frontal sinus being the primary site in only 0.3%. We report a case of adenocarcinoma arising in the frontal sinus. DESIGN: Case report. CASE REPORT: A 59-year-old woman, secretary, came in February 1998 with a 4-month history of low intensity frontal headache. She denied contact with wood dust. On examination a non-tender swelling was noted over her right forehead next to the medial aspect of the right orbit. CT scan showed a soft-tissue mass involving frontal sinus with intracranial invasion through the posterior wall. The anterior ethmoid sinus and the medial aspect of the right orbit were also involved. MRI demonstrated dural thickening in communication with the frontal mass. She underwent an en-bloc tumor resection by craniotomy including orbital clearance. Histology revealed an adenocarcinoma. After surgery she had tumor recurrence, and chemotherapy and radiotherapy were started resulting in partial improvement.


2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Ifeoluwa Apanisile ◽  
Tamás Karosi

Optic nerve astrocytomas (ONAs) are frequent types of optic nerve gliomas (ONGs), which can affect the visual pathway. An 18-year-old male patient was admitted to our department with right-sided intraorbital/retrobulbar swelling, which progressively grew over several months. Clinical examination showed right-sided diplopia, mydriasis, low visual acuity (0.4), exophthalmus (3 cm), epiphora, and severe retrobulbar pain. There was a family history of high-grade (IV) astrocytomas in which two of the family members died due to the disease. Preoperative MRI scan revealed a soft tissue mass around the retrobulbar area of the right eye with intact orbital bony walls. Surgery was performed whereby it was dissected freely from the muscles and was separated from the optic nerve and the globe. Histopathologic analysis confirmed a benign astrocytoma. The follow-up examination revealed no recurrent or residual tumor. A systemic review of the literature indicates that early diagnosis and experienced multidisciplinary management are required in case of unilateral, resectable forms of ONAs with no distant metastasis, in order to provide a long-time survival of patients. Surgical intervention of unilateral ONAs is a relatively safe procedure, allowing complete or partial tumor removal with minimal morbidity and low recurrence rate.


2016 ◽  
Vol 9 (3) ◽  
pp. 146-148
Author(s):  
Aparna Bhardwaj ◽  
Sonam Rathi

ABSTRACT Pleomorphic adenomas occurring in the nasal cavity are rarely encountered; nevertheless, there is abundance of minor seromucinous glands in that region. Most cases present with a painless, slowly progressing unilateral nasal obstruction, a nasal mass, and epistaxis. Herewith, we present an unusual case of pleomorphic adenoma arising from the lateral wall of the right nasal cavity in a 41-year-old male who complained of right nasal obstruction with no history of epistaxis. Rigid nasal endoscopy revealed a swelling continuous with right inferior concha. Computed tomography showed a well-defined, soft tissue mass in the right nasal cavity. The lesion was completely excised endoscopically. Histopathology confirmed a pleomorphic adenoma consisting of epithelial and mesenchymal elements. Wide exposure is crucial for complete excision with negative margins to achieve positive outcome and to prevent recurrence. How to cite this article Pandey AK, Bhardwaj A, Maithani T, Rathi S. Pleomorphic Adenoma of the Lateral Nasal Wall: An Unusual Entity. Clin Rhinol An Int J 2016;9(3):146-148.


2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Joseph Allencherril ◽  
Sebastian Bruera ◽  
Ronan Allencherril ◽  
Richard J. Hamill

Herein we describe the case of an elderly diabetic gentleman presenting with a two-week history of dyspnea and nonproductive cough, found to have a large left anterolateral chest wall mass. Further characterization through computed tomography (CT) of the chest revealed a soft tissue mass in the left anterior lower hemithorax found to be hepatocellular carcinoma (HCC). The liver, spleen, and pancreas were unremarkable. Diagnostic labs were unremarkable. The patient had no history of hepatitis, alcohol abuse, or illicit substance use. Pathological examination and immunohistochemical staining of the chest mass biopsy were consistent with metastatic hepatocellular carcinoma (HCC). The patient opted to pursue no further medical intervention and expired two weeks later. To the authors’ knowledge, this is one of very few descriptions of isolated hepatocellular carcinoma found in the absence of a primary liver lesion and classical risk factors for hepatocarcinogenesis. This case highlights that HCC may present independently of liver lesions seen on imaging in a patient without clear signs or symptoms of liver. HCC should be considered in cases of isolated tumors with unclear primaries as ectopic carcinogenesis and occult primary malignancy are possibilities.


2012 ◽  
Vol 25 (02) ◽  
pp. 144-148 ◽  
Author(s):  
B. Nakladal ◽  
F. vom Hagen ◽  
P. Olias ◽  
L. Brunnberg

SummaryThis report describes a case of intraosseous lipoma in a two-year-old Leonberger. The dog was presented with a history of ten month lameness in the right forelimb. A massive swelling from the elbow to the carpus of the right forelimb was visible. Treatment with anti-inflammatory medications by the local veterinarian for ten months was unsuccessful and the dog was presented at the university clinic. Radiographic images showed that the diaphyseal part of the ulna was affected by extensive cyst-like osteolysis. Furthermore, the distal metaphysis of the radius showed cyst-like osteolytic changes. The soft-tissue mass and parts of the ulna periosteum were surgically resected. Histopathological analysis of the mass in combination with clinical, surgical and radiographic findings was diagnostic for an intraosseous lipoma. The dog had a good long-term outcome as it was free of any signs of recurrence at the follow-up examinations performed after 18 months and after five years. To the authors' knowledge, this is the first description of intraosseous lipoma in a dog.


Author(s):  
Shakib H. Sheikh ◽  
Arti Raut ◽  
Savita Pohekar ◽  
Dipali Ghungrud ◽  
Swapna Morey

Background: A rarity of form of vasculitis, also known as TAK, induces inflammation in the walls of the major arteries in the body: the aorta and its main branches. The disease results from a body attack and inflammation of the walls of the arteries caused by the body's own immune system. Case Presentation: A 37-years-old women had complaints of fever, giddiness, weakness of right upper limb and lower limb since1 day. After undergoing whole blood count, liver function examination, renal and MRI function checks, CT scan, angiography, etc. was studied. She was diagnosed with takayasu arteritis.  She had past medical history of neck pain and numbness since January 2020. For these complaints her family members referred her in private hospital. There is no significant history of surgery in present, lower segment caesarean section and piles operation was done previously. Physical findings were normal except the Glasgow Coma Scale score was 11 that is, patient  was semi-conscious, In General appearance patient activity was dull and weak due disease condition, Patient’s all routine investigations were normal except few like Total WBC count was increased (21,500cell /cm) due to increased infection, Granulocytes were increased  that is 75 % due to infection and autoimmune disease, ESR was increased  that is52mm/h. Angiography showed block in the right common carotid artery, MRI- showed Acute infract in left fronto  temporo parietal region involving insular par ventricular white matter,  absent flow in distal M1 segment of MCA. Conclusion: The most frequently involved arteries and the angiographic trends in this Takayasu Arteritis study were subclavian arteries and carotid arteries. The difference between angiographic characteristics may lead to clinical differences. Operations and surgery should be carried out at various points in the course of the disease.


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