Psycho-Vegetative Status and Plasma Catecholamines in the Men with Acute Coronary Syndrome

10.12737/5922 ◽  
2014 ◽  
Vol 21 (3) ◽  
pp. 146-149
Author(s):  
Алексеев ◽  
D. Alekseev ◽  
Лиман ◽  
T. Liman ◽  
Виноградов ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
High Frequency ◽  
Depressive Disorders ◽  
Frequency Component ◽  
High Frequency Component ◽  
Coronary Syndrome ◽  
Fatal Myocardial Infarction

The authors analyzed the manifestations of anxiety and depressive disorders, disturbance of autonomic regulation and changes in the level of catecholamines in the blood of patients with acute coronary syndrome from the perspective of outcomes of the disease. 102 men with a diagnosis of acute coronary syndrome were examined. Blood samples for the determination of catecholamines (epinephrine, norepinephrine, dopamine) was performed at admission, psychological examination and scrutiny of heart rate variability was performed on the third-fourth day of the hospitalization. All patients were divided into three groups. The first group was executed on 14 (13,7%) patients who had fatal myocardial infarction developed during hospitalization. In the second group there were 40 (47,1%) patients with non-fatal myocardial infarction. The third group included 48 (47,1%) patients with unstable angina. It was shown, that levels of anxiety and depression were inverse correlated with the concentration of dopamine in the plasma, and adrenaline levels are positively correlated with indicators of overall heart rate variability and its high frequency component. Thus, in patients with acute coronary syndrome, who developed myocardial infarction the incidence and severity of anxiety and depressive disorders is substantially lower than in patients with unstable angina. Increase in high frequency component of heart rate variability was more typical for patients with acute coronary syndrome who developed fatal myocardial infarction during hospitalization. High levels of dopamine in the blood plasma are typical for patients with nonfatal myocardial infarction.

scholarly journals THE EFFECTS OF AGOMELATINE ON HEART RATE VARIABILITY IN PATIENTS WITH ANXIETY-DEPRESSIVE DISORDERS WHO SUFFERED ACUTE CORONARY SYNDROME

2018 ◽  
Vol 33 (3) ◽  
pp. 36-45 ◽  
Author(s):  
T. M. Poponina ◽  
K. I. Gunderina ◽  
Yu. S. Poponina ◽  
M. V. Soldatenko
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
Sleep Quality ◽  
Mental Status ◽  
Depressive Disorders ◽  
Holter Monitoring ◽  
Coronary Syndrome ◽  
Group 2

Aim: to study the changes in heart rate variability (HRV) in patients with anxiety and depressive disorders who suffered acute coronary syndrome (ACS) and to determine the effects of antidepressant agomelatine on HRV and sleep quality during six-month follow up.Material and Methods. The study included 54 people with ACS, anxiety, and depressive disorders. Patients were randomly assigned to two groups. Antidepressant agomelatine 25 mg/day was administered to patients of group 1 in addition to standard therapy for ACS; group 2 received placebo. Twenty four-hour Holter ECG monitoring, HRV study, mental status monitoring, and sleep quality assessment were performed during hospitalization and at six-month follow up.Results. Patients of both groups had clinically significant anxiety, subclinical depression, and insomnia of varying severity. According to Holter monitoring data, all patients had decline in HRV parameters. After six months, anxiety and depression significantly improved in patients administered with agomelatine; these patients had sleep normalization and improved HRV. The comparison group did not have similar changes.Conclusion. Additional administration of agomelatine 25 mg/day to patients with anxiety and depressive disorders after ACS resulted in improvement of mental status, heart rate variability, and sleep quality. Due to the absence of pro-arrhythmogenic effects, administration of agomelatine allows to correct anxiety-depressive disorders in patients with ACS.

scholarly journals Heart Rate Variability Using The Analgesia Nociception Index as A Predictor of Illness Severity and Mortality in Critically Ill Patients with COVID-19.

2020 ◽  
Author(s):  
Cristian Aragón-Benedí ◽  
Pablo Oliver-Forniés ◽  
Felice Galluccio ◽  
Ece Yamak Altinpulluk ◽  
Tolga Ergonenc ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
High Frequency ◽  
Frequency Component ◽  
High Frequency Component ◽  
Autonomic Nervous

Abstract Introduction A balance between the autonomic nervous system and the immune system against SARS-COV-2 is critical in the resolution of its severe macrophage proinflammatory activation. To demonstrate that most severely ill COVID-19 patients will show a depletion of the sympathetic nervous system and a predominance of parasympathetic tone. We hypothesized that a low energy of an autonomic nervous system and a high level of the high frequency component of heart rate variability may be related to the number of proinflammatory cytokines and could have a predictive value in terms of severity and mortality in critically ill patients suffering from COVID-19; Materials and Methods Single-centre, prospective, observational pilot study which included COVID-19 patients admitted to the Surgical Intensive Care Unit. High frequency (HF) component of heart rate variability (HRV) and energy of the autonomic nervous system were recorded using analgesia nociception index monitor (ANI). To estimate the severity and mortality we used the SOFA score and the date of discharge or date of death.Results A total of fourteen patients were finally included in the study. High-frequency component of heart rate variability (ANIm) were higher in the non-survivor group (p = 0.003) and were correlated with higher IL-6 levels (p = 0.002) Energy was inversely correlated with SOFA (p = 0.029). Limit value at 80 of ANIm, predicted mortalities with the sensitivity of 100% and specificity of 85.7%. In the case of energy, a limit value of 0.41 predicted mortality with all predictive values of 71.4%.Conclusion The different components of the spectral analysis of HRV allow us to infer the association between the autonomic nervous system and critically ill patients’ immune system. A low autonomic nervous system activity and a predominance of the parasympathetic system due to sympathetic depletion in patients are associated with a worse prognosis and higher mortality.

Relation between Major and Minor Depression and Heart Rate, Heart-Rate Variability, and Clinical Characteristics of Patients with Acute Coronary Syndrome

2007 ◽  
Vol 100 (3_suppl) ◽  
pp. 1245-1254 ◽  
Author(s):  
Katija Čatipović-Veselica ◽  
Andrea Galić ◽  
Krešimir Jelić ◽  
Vedrana Baraban-Glavaš ◽  
Sandra Šarić ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
Clinical Characteristics ◽  
Minor Depression ◽  
St Segment Elevation ◽  
Coronary Syndrome ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment

This study examined the prevalence of major and minor depression in patients with acute coronary syndrome and their relation with heart rate and heart-rate variability, and clinical characteristics. The study group included 297 patients, 200 men and 97 women, between ages of 21 and 70 years ( M age = 57.5 ± 9.6), who were admitted to a coronary care unit with acute coronary syndrome and survived to discharge from the hospital. Major and minor depression were diagnosed using DSM-IV. There were 44.1% patients with acute coronary syndrome without depression, 29.3% with minor depression, and 26.6% with major depression. The prevalence of minor and major depression was more elevated in patients with non-ST-segment elevation myocardial infarction and unstable angina than in patients with ST-segment elevation myocardial infarction. Ventricular fibrillation and atrial fibrillation were more common in patients with major and minor depression than in patients without depression. The 24-hr. duration of heart-beat intervals and heart-rate variability were significantly lower in patients with major and minor depression than in patients without depression. This study implies that clinical depression was significantly comorbid with the acute coronary syndrome and was related to hypertension, diabetes mellitus, age, sex, type of acute coronary syndrome, left ventricular failure, higher heart rate, and lower heart-rate variability.

Effects of 2-Hz and 100-Hz Electroacupuncture Stimulation on Respiratory Function and Heart Rate Variability: A Randomized Crossover Study

2021 ◽  
Author(s):  
Kazufumi Takahashi ◽  
Xiaoming Wang ◽  
Daiyu Shginohara ◽  
Kenji Imai
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Respiratory Function ◽  
Low Frequency ◽  
Frequency Component ◽  
Autonomic Nerve ◽  
High Frequency Component ◽  
Respiratory Function Test ◽  
Function Test

Background: Bronchial contraction and dilation is thought to be caused by non-adrenergic non-cholinergic nerves. Objective: To investigate the effects of low-frequency (1-5 Hz) and high frequency (50-100 Hz) electric acupuncture (EA) stimulation on bronchial dilation. Design: Prospective, single-center study. Setting: Teikyo Heisei University Subjects: Seventeen healthy male adults Randomization: We randomly assigned subjects to 2-Hz EA and 100-Hz EA groups in a crossover trial. The washout period was 2 weeks. Intervention: Both groups underwent a respiratory function test, followed by a 5-minute rest, followed a 5-minute rest or EA stimulation, followed by a 5- min rest. Heart rate variability was measured at rest, followed by another respiratory function test. Acupuncture was delivered near the cervical ganglia at the level of the sixth cervical vertebra on the left side. EA stimuli were set to 2-Hz or 100-Hz, and stimulation intensity was set to a level where no pain was felt. Main outcome measures: Spirometry (forced vital capacity, forced expiratory volume in 1 s, and maximum respiratory flow), autonomic nerve activity (low-frequency component, high-frequency component, and their ratio), and heart rate variability. Results: Heart rate variability analysis showed significant differences in heart rate between the 2-Hz EA and 100-Hz EA groups. The 2-Hz EA group showed a significant increase in HF. Conclusions: 2-Hz EA stimulation resulted in decreased heart rate and increased HF during stimulation. This may be more effective for regulation of the autonomic nerves of the cardiopulmonary system than 100-Hz EA stimulation. Future studies are required to confirm our findings.

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