Orbital Cellulitis in West Texas

Purpose: Identify the risk factors, microbiology, complications, and treatment outcomes of orbital cellulitis in West Texas Study type: Retrospective chart review Main findings: 46 patients over a 10-year period were treated for orbital cellulitis. The majority of patients were adult and male. The most common causative organisms were staphylococcus aureus and polymicrobial infections. Abscess formation, either subperiosteal or intraorbital, were the most common complications. The majority of patients regained normal visual acuity following resolution of the infection. Conclusion: Prompt treatment of orbital cellulitis results in limited complications and resolution of visual loss

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Lesion-Mapping Software for the Measurement of Subperiosteal Abscess Volume for Pediatric Orbital Cellulitis: A Retrospective Chart Review

Ophthalmology and Therapy ◽

10.1007/s40123-021-00333-6 ◽

2021 ◽

Author(s):

Tejus Pradeep ◽

Gagan Kalra ◽

Joseph K. Leader ◽

Jennifer McCoy ◽

Ronak Dixit ◽

...

Keyword(s):

Chart Review ◽

Retrospective Chart Review ◽

Orbital Cellulitis ◽

Subperiosteal Abscess ◽

Mapping Software ◽

Lesion Mapping

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Biofilm Formation by and Antifungal Susceptibility of Candida Isolates from Urine

Applied and Environmental Microbiology ◽

10.1128/aem.02439-06 ◽

2007 ◽

Vol 73 (6) ◽

pp. 1697-1703 ◽

Cited By ~ 86

Author(s):

N. Jain ◽

R. Kohli ◽

E. Cook ◽

P. Gialanella ◽

T. Chang ◽

...

Keyword(s):

Risk Factors ◽

Growth Medium ◽

Biofilm Formation ◽

Chart Review ◽

Antifungal Susceptibility ◽

Retrospective Chart Review ◽

Urine Samples ◽

Rpmi Medium

ABSTRACT Biofilm formation (BF) in the setting of candiduria has not been well studied. We determined BF and MIC to antifungals in Candida spp. isolates grown from urine samples of patients and performed a retrospective chart review to examine the correlation with risk factors. A total of 67 Candida spp. isolates were grown from urine samples from 55 patients. The species distribution was C. albicans (54%), C. glabrata (36%), and C. tropicalis (10%). BF varied greatly among individual Candida isolates but was stable in sequential isolates during chronic infection. BF also depended on the growth medium and especially in C. albicans was significantly enhanced in artificial urine (AU) compared to RPMI medium. In nine of the C. albicans strains BF was 4- to 10-fold higher in AU, whereas in three of the C. albicans strains and two of the C. glabrata strains higher BF was measured in RPMI medium than in AU. Determination of the MICs showed that planktonic cells of all strains were susceptible to amphotericin B (AMB) and caspofungin (CASPO) and that three of the C. glabrata strains and two of the C. albicans strains were resistant to fluconazole (FLU). In contrast, all biofilm-associated adherent cells were resistant to CASPO and FLU. The biofilms of 14 strains (28%) were sensitive to AMB (MIC50 of <1 μg/ml). Correlation between degree of BF and MIC of AMB was not seen in RPMI grown biofilms but was present when grown in AU. A retrospective chart review demonstrated no correlation of known risk factors of candiduria with BF in AU or RPMI. We conclude that BF is a stable characteristic of Candida strains that varies greatly among clinical strains and is dependent on the growth medium. Resistance to AMB is associated with higher BF in AU, which may represent the more physiologic medium to test BF. Future studies should address whether in vitro BF can predict treatment failure in vivo.

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Risk factors for poor outcomes of early rehabilitation after total en bloc spondylectomy: a retrospective chart review of 140 patients

Spinal Cord ◽

10.1038/s41393-020-0440-8 ◽

2020 ◽

Vol 58 (8) ◽

pp. 900-907

Author(s):

Yuki Kurokawa ◽

Hideki Murakami ◽

Satoru Demura ◽

Satoshi Kato ◽

Noriaki Yokogawa ◽

...

Keyword(s):

Risk Factors ◽

Chart Review ◽

Retrospective Chart Review ◽

Early Rehabilitation ◽

En Bloc ◽

Total En Bloc Spondylectomy ◽

En Bloc Spondylectomy ◽

Bloc Spondylectomy ◽

Poor Outcomes

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Exposure to risk factors for cervical and anal dysplasia in transgender men and women: A retrospective chart review

Gynecologic Oncology ◽

10.1016/j.ygyno.2017.03.170 ◽

2017 ◽

Vol 145 ◽

pp. 72 ◽

Cited By ~ 1

Author(s):

L.A. Fein ◽

L. Abern ◽

J. Seay ◽

C.A. Medina ◽

C.J. Salgado ◽

...

Keyword(s):

Risk Factors ◽

Chart Review ◽

Retrospective Chart Review ◽

Men And Women ◽

Anal Dysplasia ◽

Transgender Men

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High Prevalence of Hypertension in Ethiopian and Non-Ethiopian HIV-Infected Adults

International Journal of Hypertension ◽

10.1155/2018/8637101 ◽

2018 ◽

Vol 2018 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Maya Korem ◽

Tali Wallach ◽

Michael Bursztyn ◽

Shlomo Maayan ◽

Karen Olshtain-Pops

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Chart Review ◽

Pressure Rise ◽

Retrospective Chart Review ◽

Close Monitoring ◽

Related Factors ◽

The Metabolic Syndrome ◽

High Prevalence ◽

Study Population

Objectives. Prevalence of hypertension has not been studied in the Ethiopian HIV-infected population, which represents 60% of the patients in our AIDS unit. Our aim was to identify risk factors and characterize the prevalence of hypertension in the population monitored at our unit. Methods. A retrospective chart review categorized subjects according to their blood pressure levels. Hypertension prevalence was determined and stratified according to variables perceived to contribute to elevated blood pressure. Results. The prevalence of hypertension in our study population was significantly higher compared to the general population (53% versus 20%, P<0.0001) and was associated with known risk factors and not with patients’ viral load and CD4 levels. Ethiopian HIV-infected adults had a prominently higher rate of blood pressure rise over time as compared to non-Ethiopians (P=0.016). Conclusions. The high prevalence of hypertension in this cohort and the rapid increase in blood pressure in Ethiopians are alarming. We could not attribute high prevalence to HIV-related factors and we presume it is part of the metabolic syndrome. The lifelong cardiovascular risk associated with HIV infection mandates hypertension screening and close monitoring in this population.

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Management of isolated calf vein thrombosis in cancer patients

Vascular ◽

10.1177/1708538115584726 ◽

2015 ◽

Vol 24 (1) ◽

pp. 64-69

Author(s):

Anand S Brahmandam ◽

Kirstyn Brownson ◽

Laura Skrip ◽

Terri Parker ◽

Jeffrey Indes ◽

...

Keyword(s):

Risk Factors ◽

Cancer Patients ◽

Chart Review ◽

Retrospective Chart Review ◽

Treatment Modalities ◽

Vein Thrombosis ◽

History Of ◽

Calf Vein ◽

History Of Cancer

The treatment of isolated calf vein thrombosis remains widely debated. This study highlights the characteristics of isolated calf vein thrombosis in cancer patients and compares to isolated calf vein thrombosis in patients without history of cancer. Between July 2013 and April 2014, a retrospective chart review of consecutive patients with isolated calf vein thrombosis was performed recording patient risk factors, ultrasound characteristics of the thrombus, treatment modalities, long-term recurrence of venous-thromboembolism, incidence of bleeding, and mortality. Of 131 patients with isolated calf vein thrombosis, 53 (40.1%) had history of cancer. Isolated calf vein thrombosis occurred at an older age in cancer patients (66.7 vs 58.5 years, p = 0.004). The anatomical characteristics of isolated calf vein thrombosis on ultrasound were comparable in both groups. Isolated calf vein thrombosis in cancer patients was less likely to be treated with anticoagulation (60.4% vs 80.8%, p = 0.018). However, a trend towards higher incidence of bleeding after initiation of anticoagulation for isolated calf vein thrombosis in cancer patients (11.3% vs 6.4%, p = 0.351) was noted. Mortality in cancer patients was higher (37.7% vs 9.00%, p < 0.001) but was unrelated to isolated calf vein thrombosis or its treatment. In conclusion, the risks of bleeding seem to exceed the benefits of anticoagulation in approximately 50% of cancer patients with isolated calf vein thrombosis. The management of isolated calf vein thrombosis does not seem to impact the survival of cancer patients.

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Incidence and risk factors for complications after definitive skeletal fixation of lower extremity in multiple injury patients: a retrospective chart review

F1000Research ◽

10.12688/f1000research.14825.1 ◽

2018 ◽

Vol 7 ◽

pp. 612 ◽

Cited By ~ 2

Author(s):

Thananit Sangkomkamhang ◽

Wilaiphorn Thinkhamrop ◽

Bandit Thinkhamrop ◽

Wongsa Laohasiriwong

Keyword(s):

Risk Factors ◽

Lower Extremity ◽

Early Treatment ◽

Chart Review ◽

Retrospective Chart Review ◽

Multiple Injuries ◽

Major Complications ◽

Severity Of Injury ◽

Initial Injury ◽

The Mean

Background: The management of multiple injuries is complex. Type and timing of treatment for lower extremity fractures is a controversial subject. Although many studies have demonstrated the safety and effectiveness of early treatment, others have suggested that early definitive stabilization may cause complications, especially with chest and head injuries. The aim of this study was to determine the complications and effects of timing of fixation, and investigate risk factors for complications in multiple injuries patients with lower extremity fractures. Methods: A Retrospective chart review from Khon Kaen Trauma Registry between 2008 and 2015 were collected. All major complications were identified and collected for example acute respiratory distress syndrome (ARDS), acute kidney injury (AKI) and sepsis. The time to definitive skeletal fixation from initial injury was identified and analyzed with multiple logistic regression. Results: 1224 multiple injuries patients with lower extremity fractures were identified. The mean age was 34±19.5 years, 74.4% were male and 25.6% female. The mean time from initial injury to definitive operation was 55.7±53.9 hours. Complications occurred with 178 patients (14.5%), the most common of which were pneumonia, ARDS and AKI. After adjusting for sex, severity of injury, we found that the operation within 24-48 hours complication was 6.67 times less common than in the early treatment group (less than 24 hours) (95% CI: 3.03 to 10.00, P-value< 0.001). Conclusions: About 15% of the multiple injuries patients with lower extremity fracture had major complications. The optimal time for definitive fixation in lower extremity fractures to reduce complications was within 24-48 hours. We found that if we operated too early (before 24 hours) or more than 48 hours after the injury it could increase the morbidity and mortality.

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An Ophthalmology Resident-Led Quality Improvement Initiative to Decrease the Incidence of Perioperative Corneal Injury

Journal of Academic Ophthalmology ◽

10.1055/s-0039-3400545 ◽

2019 ◽

Vol 11 (02) ◽

pp. e49-e53

Author(s):

Amanda L. Ely ◽

Mark Goerlitz-Jessen ◽

Ingrid U. Scott ◽

Erik Lehman ◽

Tabassum Ali ◽

...

Keyword(s):

Risk Factors ◽

Quality Improvement ◽

Chart Review ◽

Medical Center ◽

Academic Medical Center ◽

Retrospective Chart Review ◽

Corneal Injury ◽

Surgical Case ◽

Anesthesia Providers ◽

Academic Medical

Abstract Objective This article evaluates the effectiveness of an ophthalmology resident-led quality improvement (QI) initiative to decrease the incidence of perioperative corneal injury at an academic medical center Design Retrospective chart review. Methods A retrospective chart review was conducted of all surgical cases performed 6 months prior to, and 6 months after, implementation of an ophthalmology resident-led QI initiative at an academic medical center. The QI initiative (which focused on perioperative corneal injury awareness, understanding of risk factors, and presentation of an algorithm designed to prevent perioperative corneal injury) consisted of a lecture and distribution of educational materials to anesthesia providers. Data collected through the chart review included type of surgical case, presence of diabetes mellitus or thyroid disease, patient age and gender, patient positioning (supine, prone, or lateral), level of anesthesia provider training, length of surgical case, surgical service, type of anesthesia, and type (if any) of perioperative eye injury. The rates of perioperative corneal injury pre- versus post-initiative were compared. Results The rates of perioperative corneal injury pre- and post-initiative were 3.7 and 1.9 per 1,000, respectively (p = 0.012). Significant risk factors for perioperative corneal injury include longer duration of surgery (odds ratio [OR] 90–180 vs. < 90 minutes = 4.18, 95% confidence interval [CI] 1.43–12.18; OR > 180 vs. < 90 minutes = 8.56, 95% CI 3.01–24.32; OR > 180 vs. 90–180 = 2.05, 95% CI 1.17–3.58), patient position lateral > prone > supine (OR prone vs. lateral = 0.25, 95% CI 0.09–0.67; OR supine vs. lateral = 0.13, 95% CI 0.07–0.23), nonhead and neck surgeries (OR = 0.32, 95% CI 0.11–0.87), and surgery performed under the general surgery service (OR general surgery service vs. other subspecialty services = 6.50, 95% CI 2.39–24.76). Conclusions An ophthalmology resident-led QI initiative consisting of educating anesthesia providers was associated with a significant decrease in the rate of perioperative corneal injury.

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26. Retrospective analysis of HIV-infected men with anal cancer attending the Toronto General Hospital Immunodeficiency Clinic, Toronto, Ontario, Canada (1985–2013)

Sexual Health ◽

10.1071/shv10n6ab26 ◽

2013 ◽

Vol 10 (6) ◽

pp. 582

Author(s):

R. Medford ◽

I. E. Salit

Keyword(s):

Risk Factors ◽

Radiation Therapy ◽

General Hospital ◽

Anal Cancer ◽

Combination Chemotherapy ◽

Chart Review ◽

Toronto General Hospital ◽

Retrospective Chart Review ◽

Incidence Rates ◽

Cd4 Count

Background The incidence of anal cancer (AC) in Canada is 1.5/100 000 but HIV-infected individuals have incidence rates from 49–144/100 000. It is important to examine risk factors for this difference. Methods: A retrospective chart review was performed to look at risk factors in patients with the diagnosis of ‘anal cancer’ attending the Toronto General Hospital Immunodeficiency Clinic (TGH-IC) in Toronto, Ontario, Canada, from 1985 to 2013. There were 5200 clinic attendees. Results: 36 (0.96%) males attending TGH-IC were diagnosed with AC between 1985 and 2013; 17 (47%) were diagnosed since 2008. 7 (19.4%) are deceased; 6 (16.7%) as a result of AC. Mean age at diagnosis was 56 ± 9.8 years compared with mean age at TGH-IC of 48 ± 15.9 years (P = 0.015). 33 (91.7%) were on anti-retroviral therapy (ART) at time of diagnosis. Compared with current ART use, 30 (90.9%) vs 727 (72.6%; P = 0.015) were on nucleoside reverse transcriptase inhibitors (NRTIs); 22 (66.7%) vs 554 (55.3%; P = 0.015) were on protease inhibitors; 8 (24.2%) vs 471 (47.0%; P = 0.015) were on NNRTIs. Median CD4 count at diagnosis was 265 cells mm–3, compared with the TGH-IC of 425 cells mm–3 (P = 0.04). A tobacco history (former or current) was found in 24 (72.7%) with AC vs 2232 (41%) without AC (P = 0.015). 35 (97.2%) underwent treatment: combination chemotherapy and radiation therapy being the most common in 23 (63.9%). Conclusions: In 28 years, there have been a total of 36 males diagnosed with anal cancer at TGH-IC. They were older, had a lower CD4 count and were more likely to be smokers. Combination chemotherapy and radiation therapy remains the mainstay of treatment for AC.

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