scholarly journals Impact of neighborhood socioeconomic status on the association between occupational radiation exposure and circulatory disease

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
G. Bustamante ◽  
T.L. Osypuk ◽  
M.R. Ramirez ◽  
R.F. MacLehose ◽  
C.M. Kitahara ◽  
...  
2020 ◽  
Vol 77 (11) ◽  
pp. 752-760
Author(s):  
Eun Shil Cha ◽  
Lydia B Zablotska ◽  
Ye Jin Bang ◽  
Won Jin Lee

ObjectivesWe investigated the association between low-dose external occupational radiation exposure and circulatory disease morbidity among diagnostic medical radiation workers.MethodsA cohort of 11 500 diagnostic medical radiation workers was linked with the National Dosimetry Registry data and the National Health Insurance Service data. Relative risks (RRs) were calculated to explore the association between occupational factors and circulatory disease morbidity, and excess relative risks per 100 milligray (ERR/100 mGy) were estimated to quantify the radiation dose-response relationship.ResultsOverall, there were 2270 cases of circulatory diseases during 93 696 person-years of observation (average follow-up=8.1 years). RRs for hypertension were significantly increased for individuals who started working before 2000 compared with those who started in 2005 and later. ERR/100 mGy for all circulatory diseases was 0.14 (95% CI −0.57 to 0.99). Radiation risks of cerebrovascular diseases and ischaemic heart disease were non-significantly increased with estimates of individual cumulative doses to the heart (ERR/100 mGy=3.10 (−0.75 to 11.59) and 1.22 (−0.71 to 4.73), respectively). However, ERR estimates were generally more strongly positive for female versus male workers and for younger workers versus more than 50-year-old workers.ConclusionsThis study provides little evidence in support of a positive association between occupational radiation exposure and the overall risk of circulatory disease over a short follow-up period among medical radiation workers in South Korea. However, significantly increased RR with earlier year first worked, elevated ERR in female workers and young workers should be further followed up.


2009 ◽  
Vol 59 (6) ◽  
pp. 437-439 ◽  
Author(s):  
K. K. Karipidis ◽  
G. Benke ◽  
M. R. Sim ◽  
L. Fritschi ◽  
C. Vajdic ◽  
...  

2013 ◽  
Vol 46 (4) ◽  
pp. 424-430 ◽  
Author(s):  
A.P. Patel ◽  
D. Gallacher ◽  
R. Dourado ◽  
O. Lyons ◽  
A. Smith ◽  
...  

2016 ◽  
Vol 63 (1) ◽  
pp. 190-197 ◽  
Author(s):  
Daniel E. Kendrick ◽  
Claire P. Miller ◽  
Pamela A. Moorehead ◽  
Ann H. Kim ◽  
Henry R. Baele ◽  
...  

2017 ◽  
Vol 75 (3) ◽  
pp. 199-204 ◽  
Author(s):  
Lucie Fournier ◽  
Enora Cléro ◽  
Eric Samson ◽  
Sylvaine Caër-Lorho ◽  
Dominique Laurier ◽  
...  

ObjectivesThe French nuclear worker cohort allows for the assessment of cancer risk associated with occupational radiation exposure, but workers are also exposed to medical and environmental radiation which can be of the same order of magnitude. This study aims to examine the impact of non-occupational radiation exposures on the dose-risk analysis between occupational radiation exposure and cancer mortality.MethodsThe cohort included workers employed before 1995 for at least one year by CEA, AREVA NC or EDF and badge-monitored for external radiation exposure. Monitoring results were used to calculate occupational individual doses. Scenarios of work-related X-ray and environmental exposures were simulated. Poisson regression was used to quantify associations between occupational exposure and cancer mortality adjusting for non-occupational radiation exposure.ResultsThe mean cumulative dose of external occupational radiation was 18.4 mSv among 59 004 workers. Depending on the hypotheses made, the mean cumulative work-related X-ray dose varied between 3.1 and 9.2 mSv and the mean cumulative environmental dose was around 130 mSv. The unadjusted excess relative rate of cancer per Sievert (ERR/Sv) was 0.34 (90% CI −0.44 to 1.24). Adjusting for environmental radiation exposure did not substantially modify this risk coefficient, but it was attenuated by medical exposure (ERR/Sv point estimate between 0.15 and 0.23).ConclusionsOccupational radiation risk estimates were lower when adjusted for work-related X-ray exposures. Environmental exposures had a very slight impact on the occupational exposure risk estimates. In any scenario of non-occupational exposure considered, a positive but insignificant excess cancer risk associated with occupational exposure was observed.


BMJ Open ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. e017359 ◽  
Author(s):  
Songwon Seo ◽  
Wan Young Lim ◽  
Dal Nim Lee ◽  
Jung Un Kim ◽  
Eun Shil Cha ◽  
...  

IntroductionThe cancer risk of radiation exposure in the moderate-to-high dose range has been well established. However, the risk remains unclear at low-dose ranges with protracted low-dose rate exposure, which is typical of occupational exposure. Several epidemiological studies of Korean radiation workers have been conducted, but the data were analysed retrospectively in most cases. Moreover, groups with relatively high exposure, such as industrial radiographers, have been neglected. Therefore, we have launched a prospective cohort study of all Korean radiation workers to assess the health effects associated with occupational radiation exposure.Methods and analysisApproximately 42 000 Korean radiation workers registered with the Nuclear Safety and Security Commission from 2016 to 2017 are the initial target population of this study. Cohort participants are to be enrolled through a nationwide self-administered questionnaire survey between 24 May 2016 and 30 June 2017. As of 31 March 2017, 22 982 workers are enrolled in the study corresponding to a response rate of 75%. This enrolment will be continued at 5-year intervals to update information on existing study participants and recruit newly hired workers. Survey data will be linked with the national dose registry, the national cancer registry, the national vital statistics registry and national health insurance data via personal identification numbers. Age-specific and sex-specific standardised incidence and mortality ratios will be calculated for overall comparisons of cancer risk. For dose–response assessment, excess relative risk (per Gy) and excess absolute risk (per Gy) will be estimated with adjustments for birth year and potential confounders, such as lifestyle factors and socioeconomic status.Ethics and disseminationThis study has received ethical approval from the institutional review board of the Korea Institute of Radiological and Medical Sciences (IRB No. K-1603-002-034). All participants provided written informed consent prior to enrolment. The findings of the study will be disseminated through scientific peer-reviewed journals and be provided to the public, including radiation workers, via the study website (http://www.rhs.kr/) and onsite radiation safety education.


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