scholarly journals More than Valley Fever: Pulmonary Actinomycosis and Coccidioidomycosis Co-infection in a Patient

Author(s):  
Abuzar Asif ◽  
Moni Roy ◽  
Sharjeel Ahmad

Pulmonary coccidioidomycosis and pulmonary actinomycosis are unheard of as co-pathogens. Infection with these organisms on their own can mimic lung cancer, thus presenting a diagnostic challenge. We present the case of a 75-year-old woman presenting with haemoptysis with a chest CT chest finding of a lung mass suggestive of lung cancer. A diagnosis of concomitant infection by Coccidioides posadasii/immitis and Actinomyces odontolyticus was made based on culture and histopathology results. The patient was successfully treated with a combination of antifungal and antibacterial therapy. This is the first reported case of co-infection by these two microorganisms.

Author(s):  
K. Miyagi ◽  
A. Nakajima ◽  
Y. Kawaguchi ◽  
O. Suzuki ◽  
S. Nakamura ◽  
...  

Author(s):  
Konstantinos Stefanidis ◽  
Elissavet Konstantelloy ◽  
Gibran Yusuf ◽  
Joanna Moser ◽  
Carol Tan ◽  
...  

Haigan ◽  
1993 ◽  
Vol 33 (7) ◽  
pp. 1031-1036
Author(s):  
Masao Ichiki ◽  
Masanori Sakurai ◽  
Izumi Hayashi ◽  
Yukitoshi Sato ◽  
Sakae Okumura ◽  
...  

2014 ◽  
Vol 21 (6) ◽  
pp. e75-e77 ◽  
Author(s):  
Smaranda Gliga ◽  
Mathilde Devaux ◽  
Marine Gosset Woimant ◽  
Dominique Mompoint ◽  
Christian Perronne ◽  
...  

Pulmonary actinomycosis is a rare disease that is often misdiag-nosed as tuberculosis or lung cancer.Actinomyces graevenitziiis a relatively new recognizedActinomycesspecies isolated from various clinical samples. The authors report a case of pulmonary actinomycosis caused byA graevenitzii. A computed tomography examination revealed an excavated consolidation in the middle right lobe of a previously healthy young man who presented with a long history of moderate cough. Cultures of the bronchoalveolar lavage fluid confirmed the diagnosis of pulmonary abscess caused byA gravenitzii. At the three-month follow-up consultation and, after six weeks of high-dose amoxicillin, the pulmonary lesion had completely disappeared.


Haigan ◽  
2011 ◽  
Vol 51 (7) ◽  
pp. 809-813 ◽  
Author(s):  
Keigo Ozono ◽  
Masaaki Inoue ◽  
Satoshi Kuboi ◽  
Masamitsu Kido ◽  
Ryoichi Nakanishi

2016 ◽  
Vol 24 (11) ◽  
pp. 4721-4726 ◽  
Author(s):  
Eun Young Kim ◽  
Young Saing Kim ◽  
Inkeun Park ◽  
Hee Kyung Ahn ◽  
Eun Kyung Cho ◽  
...  

2020 ◽  
Vol 29 ◽  
pp. 100982
Author(s):  
Asghar Ali ◽  
Sindhaghatta Venkatram ◽  
Masooma Niazi ◽  
Gilda Diaz-Fuentes
Keyword(s):  

2018 ◽  
Vol 25 (6) ◽  
Author(s):  
G. Kasymjanova ◽  
R. T. Jagoe ◽  
C. Pepe ◽  
L. Sakr ◽  
V. Cohen ◽  
...  

Introduction Radiotherapy (rt) plays an important role in the treatment of lung cancer. One of the most common comorbidities in patients with lung cancer is pulmonary emphysema. The literature offers conflicting data about whether emphysema increases the occurrence and severity of radiation pneumonitis (rp). As a result, whether high doses of rt (with curative intent) should be avoided in patients with emphysema is still unclear.Objective We measured the documented incidence of rp in patients with and without emphysema who received curative radiation treatment.Methods This retrospective cohort study considered patients in the lung cancer clinical database of the Peter Brojde Lung Cancer Centre. Data from the database has been used previously for research studies, including a recent publication about emphysema grading, based on the percentage of lung occupied by emphysema on computed tomography (ct) imaging.Results Using previously published methods, chest ct imaging for 498 patients with lung cancer was scored for the presence of emphysema. The analysis considered 114 patients who received at least 30 Gy radiation. Of those 114 patients, 64 (56%) had emphysema, with approximately 23% having severe or very severe disease. The incidence of rp was 34.4% in patients with emphysema (n = 22) and 32.0% in patients with no emphysema (n = 16, p = 0.48). No difference in the incidence of rp was evident between patients with various grades of emphysema (p = 0.96). Similarly, no difference in the incidence of rp was evident between the two treatment protocols—that is, definitive rt 17 (37%) and combined chemotherapy–rt 21 (31%, p = 0.5).Conclusions In our cohort, the presence of emphysema on chest ct imaging was not associated with an increased risk of rp. That finding suggests that patients with lung cancer and emphysema should be offered rt when clinically indicated. However, further prospective studies will be needed for confirmation.


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