Six-minute walk test and incremental shuttle walk test in the evaluation of functional capacity in Chagas heart disease

Background. Bronchiectasis is a chronic respiratory condition characterised by chronic sputum production, fatigue, and dyspnoea. These symptoms will lead to reduced exercise capacity and a reduced ability to carry out activities of daily living. Glittre ADL test is a valid and reliable test which evaluates the activities of daily living. Aim. To investigate whether the Glittre ADL test can differentiate the functional capacity and cardiorespiratory responses of patients with bronchiectasis from those healthy individuals using the six-minute test as a functional performance standard. Methods. This study included 30 subjects: 15 bronchiectasis and 15 age- and gender-matched healthy subjects. The patients and healthy subjects were made to perform the Glittre ADL and six-minute test on two consecutive days. Parameters such as time taken, distance walked, HR, RR, SpO2, and dyspnoea were recorded before and after the tests. Results. The performance of bronchiectasis was worse than the healthy group on the Glittre ADL test (4.78 ± 1.33 min, 3.94 ± 0.82 min, p=0.04). Distance walked in the six-minute walk test by the bronchiectasis was 42 meters lesser than the healthy (400.33 ± 77.99, 442 ± 89.21, p=0.18). The Glittre ADL test was correlated with 6MWT when the total sample was analysed (r=−0.41,p=0.05). There was moderate positive correlation between heart rate variation, dyspnoea, respiratory rate, and peripheral saturation (SpO2) between the tests (Glittre heart rate versus six-minute walk test heart rate (r=0.55,p=0.001); Glittre (Borg) versus six-minute walk test (Borg) (r=0.72,p=0.00); Glittre respiratory rate versus six-minute walk test RR (r=0.62,p=0.00); Glittre SpO2 versus six-minute walk test SpO2 (r=0.40,p=0.02)). The bronchiectasis group had a statistically significant higher (p=0.08,p=0.46) increase in dyspnoea and RR than the controls in both the Glittre ADL test and six-minute walk test (p=0.009,p=0.03), with the similar HR variation in both the groups (p>0.05). There was statistical difference in peripheral oxygen saturation in bronchiectasis in the six-minute walk test (p=0.03). Conclusion. The Glittre ADL test induced similar cardiorespiratory responses when compared to the six-minute walk test. So, the Glittre ADL test can be used as an assessment tool besides the six-minute walk test for the more complete evaluation of functional capacity and activities of daily living.

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Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease

European Journal of Heart Failure ◽

10.1016/j.ejheart.2005.08.006 ◽

2006 ◽

Vol 8 (3) ◽

pp. 321-325 ◽

Cited By ~ 36

Author(s):

L. Ingle ◽

A.S. Rigby ◽

S. Nabb ◽

P.K. Jones ◽

A.L. Clark ◽

...

Keyword(s):

Heart Disease ◽

Test Performance ◽

Left Ventricular Systolic Dysfunction ◽

Systolic Dysfunction ◽

Structural Heart Disease ◽

Left Ventricular ◽

Walk Test ◽

Ventricular Systolic Dysfunction ◽

Six Minute Walk Test ◽

Minute Walk

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Six Minute Walk Test to assess functional capacity in chronic liver disease patients

World Journal of Gastroenterology ◽

10.3748/wjg.v13.i29.3996 ◽

2007 ◽

Vol 13 (29) ◽

pp. 3996 ◽

Cited By ~ 57

Author(s):

Hatem F Alameri

Keyword(s):

Liver Disease ◽

Chronic Liver Disease ◽

Functional Capacity ◽

Chronic Liver ◽

Walk Test ◽

Six Minute Walk Test ◽

Minute Walk

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Abstract 005: Six-Minute Walk Test Predicts Heart Failure, Myocardial Infarction, and Death in Patients with Stable Ischemic Heart Disease: Data from the Heart and Soul Study

Circulation ◽

10.1161/circ.125.suppl_10.a005 ◽

2012 ◽

Vol 125 (suppl_10) ◽

Author(s):

Alexis L Beatty ◽

Nelson B Schiller ◽

Mary A Whooley

Keyword(s):

Myocardial Infarction ◽

Heart Failure ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Exercise Capacity ◽

Treadmill Exercise ◽

Walk Test ◽

Six Minute Walk Test ◽

6Mwt Distance ◽

Minute Walk

Background: The six-minute walk test (6MWT) is commonly used to assess functional exercise capacity in patients with heart or lung disease. However, its ability to predict events in patients with stable ischemic heart disease (IHD) is unknown. Methods: We measured 6MWT distance and treadmill exercise capacity in 556 outpatients with stable IHD between September 2000 and December 2002. Participants were followed for an average of 7.7 years to determine cardiovascular (CV) events (myocardial infarction, heart failure, or death). We used Cox proportional hazards models to evaluate 6MWT distance and treadmill exercise capacity as predictors of subsequent events. Results: Among the 556 patients, there were 82 heart failure hospitalizations, 63 myocardial infarctions, and 184 deaths from any cause. Patients in the lowest quartile of 6MWT distance (284-1375 ft) were 3 times as likely as patients in the highest quartile (1786-2746 ft) to experience CV events (62% vs. 22%, age-adjusted HR 3.15, 95%CI 1.98-5.03, p<0.0001). Each standard deviation (SD) decrease in 6MWT distance (342 ft) was associated with an 86% greater risk of heart failure (age-adjusted HR 1.86, 95%CI 1.51-2.31, p<0.0001), a 47% greater risk of myocardial infarction (age-adjusted HR 1.47, 95%CI 1.15-1.89, p=0.002), a 54% greater risk of death (age-adjusted HR 1.54, 95%CI 1.32-1.80, p<0.0001), and a 55% greater risk of any event (age-adjusted HR 1.55, 95%CI 1.35-1.78, p<0.0001). After adjustment for traditional risk factors and measures of cardiac disease severity (left ventricular ejection fraction, inducible ischemia, diastolic dysfunction, NT-proBNP and CRP), each SD decrease in 6MWT remained associated with a 38% greater risk of CV events (HR 1.38, 95%CI 1.10-1.74, p=0.005). 6MWT distance was similar to treadmill exercise capacity for predicting CV events (age-adjusted c-statistics 0.72 vs. 0.71, p=0.73 for comparison). Conclusions: Distance walked on 6MWT is as good as treadmill exercise capacity for predicting CV events in patients with stable IHD.

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