A Review of Genetic and Epigenetic Mechanisms in Heavy Metal Carcinogenesis: Nickel and Cadmium

2013 ◽  
Vol 1 (8) ◽  
pp. 202-216 ◽  
Author(s):  
Zienab Saed ◽  
Shahin Gavanji ◽  
Sahar Davodi
Keyword(s):  
Heavy Metal ◽  
Epigenetic Mechanisms ◽  
Metal Carcinogenesis

scholarly journals Epigenetic Control of Plant Response to Heavy Metal Stress: A New View on Aluminum Tolerance

2020 ◽  
Vol 11 ◽  
Author(s):  
Jenny Johana Gallo-Franco ◽  
Chrystian Camilo Sosa ◽  
Thaura Ghneim-Herrera ◽  
Mauricio Quimbaya
Keyword(s):  
Heavy Metal ◽  
Abiotic Stress ◽  
Stress Responses ◽  
Crop Production ◽  
Acid Soils ◽  
Molecular Evidence ◽  
Published Data ◽  
Epigenetic Mechanisms ◽  
Al Tolerance ◽  
Rice Varieties

High concentrations of heavy metal (HM) ions impact agronomic staple crop production in acid soils (pH ≤ 5) due to their cytotoxic, genotoxic, and mutagenic effects. Among cytotoxic ions, the trivalent aluminum cation (Al3+) formed by solubilization of aluminum (Al) into acid soils, is one of the most abundant and toxic elements under acidic conditions. In recent years, several studies have elucidated the different signal transduction pathways involved in HM responses, identifying complementary genetic mechanisms conferring tolerance to plants. Although epigenetics has become more relevant in abiotic stress studies, epigenetic mechanisms underlying plant responses to HM stress remain poorly understood. This review describes the main epigenetic mechanisms related to crop responses during stress conditions, specifically, the molecular evidence showing how epigenetics is at the core of plant adaptation responses to HM ions. We highlight the epigenetic mechanisms that induce Al tolerance. Likewise, we analyze the pivotal relationship between epigenetic and genetic factors associated with HM tolerance. Finally, using rice as a study case, we performed a general analysis over previously whole-genome bisulfite-seq published data. Specific genes related to Al tolerance, measured in contrasting tolerant and susceptible rice varieties, exhibited differences in DNA methylation frequency. The differential methylation patterns could be associated with epigenetic regulation of rice responses to Al stress, highlighting the major role of epigenetics over specific abiotic stress responses.

Complementary Z-Contrast Imaging and Digital Image Processing

1985 ◽  
Vol 43 ◽  
pp. 304-305
Author(s):  
K. N. Colonna ◽  
G. Oliphant
Keyword(s):  
Image Processing ◽  
Heavy Metal ◽  
Digital Image Processing ◽  
Digital Image ◽  
Biological Tissue ◽  
Biological Imaging ◽  
Tissue Preparation ◽  
Contrast Imaging ◽  
Imaging Tool ◽  
Z Contrast

Harmonious use of Z-contrast imaging and digital image processing as an analytical imaging tool was developed and demonstrated in studying the elemental constitution of human and maturing rabbit spermatozoa. Due to its analog origin (Fig. 1), the Z-contrast image offers information unique to the science of biological imaging. Despite the information and distinct advantages it offers, the potential of Z-contrast imaging is extremely limited without the application of techniques of digital image processing. For the first time in biological imaging, this study demonstrates the tremendous potential involved in the complementary use of Z-contrast imaging and digital image processing.Imaging in the Z-contrast mode is powerful for three distinct reasons, the first of which involves tissue preparation. It affords biologists the opportunity to visualize biological tissue without the use of heavy metal fixatives and stains. For years biologists have used heavy metal components to compensate for the limited electron scattering properties of biological tissue.

Recent Progress In High-Resolution Shadowing For Biological Transmission Electron Microscopy

1990 ◽  
Vol 48 (1) ◽  
pp. 510-511 ◽  
Author(s):  
Heinz Gross ◽  
Katarina Krusche ◽  
Peter Tittmann
Keyword(s):  
Heavy Metal ◽  
High Resolution ◽  
Freeze Drying ◽  
Atmospheric Conditions ◽  
Vacuum Equipment ◽  
Transmission Electron ◽  
Gas Atmosphere ◽  
Gas Molecules ◽  
Residual Gas ◽  
Backing Layer

Freeze-drying followed by heavy metal shadowing is a long established and straight forward approach to routinely study the structure of dehydrated macromolecules. Very thin specimens such as isolated membranes or single macromolecules are directly adsorbed on C-coated grids. After rapid freezing the grids are transferred into a suitable vacuum equipment for freeze-drying and heavy metal shadowing.To improve the resolution power of shadowing films we introduced shadowing at very low specimen temperature (−250°C). To routinely do that without the danger of contamination we developed in collaboration with Balzers an UHV (p≤10-9 mbar) machine (BAF500K, Fig.2). It should be mentioned here that at −250°C the specimen surface acts as effective cryopump for practically all impinging residual gas molecules from the residual gas atmosphere.Common high resolution shadowing films (Pt/C, Ta/W) have to be protected from alterations due to air contact by a relatively thick C-backing layer, when transferred via atmospheric conditions into the TEM. Such an additional C-coat contributes disturbingly to the contrast at high resolution.

Heavy Metal Tales

2008 ◽  
Vol 42 (2) ◽  
pp. 24
Author(s):  
WILLIAM G. WILKOFF
Keyword(s):  
Heavy Metal

Musik und Gesundheit

2010 ◽  
Vol 21 (1) ◽  
pp. 1-6
Author(s):  
Hans-Joachim Trappe
Keyword(s):  
Heavy Metal ◽  
Physiologische Parameter

Zusammenfassung. Musik (M) spielt im Leben eines jeden Menschen nicht nur eine wichtige Rolle, sondern hat auch Effekte auf Herzfrequenz (HF), Herzfrequenzvariabilität (HRV) und auf andere physiologische Parameter. Bei Musikern sind die Beeinflussungen von HF, HRV und autonomen Nervensystem größer als bei Musik-Zuhörern. Obgleich M als subjektives Empfinden zu interpretieren ist, zeigen Studien, dass objektive Parameter unter verschiedenen Umständen eindeutig durch Musik beeinflusst werden. Es wurde nachgewiesen, dass M als Prämedikation zu einer signifikant niedrigen Ängstlichkeitsrate führte als Midazolam (p < 0,001). M wird auch bei anderen Situationen eingesetzt, bei depressiven Menschen, alten Menschen, zur Schmerztherapie und im Rahmen der Intensiv- bzw. Palliativmedizin. M sollte jedoch individuell nach den Wünschen der Pt ausgewählt werden. Nur so lassen sich die gewünschten Effekte erreichen, Ängste vermeiden und führen zu einer Verbesserung der Lebensqualität (QoL). Die besten M-Effekte sind durch klassische oder meditative M zu erreichen, Heavy Metal or Techno-M ist ineffektiv oder gar schädlich und kann zu Stress oder lebensgefährlichen Arrhythmien führen. Es gibt viele Komponisten, deren M zu einer Verbesserung der QoL führt, besonders Bach, Mozart oder italienische Komponisten sind hier zu nennen.

Heavy metal binding by mycorrhizal fungi

1994 ◽  
Vol 92 (2) ◽  
pp. 364-368 ◽  
Author(s):  
Ulrich Galli ◽  
Hannes Schuepp ◽  
Christian Brunold
Keyword(s):  
Heavy Metal ◽  
Metal Binding ◽  
Mycorrhizal Fungi ◽  
Heavy Metal Binding
Sign in / Sign up

Export Citation Format

Share Document