THE EFFECTS OF PARTICULATE COBALT, CHROMIUM AND COBALT-CHROMIUM ALLOY ON HUMAN OSTEOBLAST-LIKE CELLS IN VITRO

The ability to penetrate conditionally pathogenic microflora from defects of the oral mucosa, from the surface of dentures and tissues of the prosthetic bed into the bloodstream is extremely dangerous for the body. The method of evaluation of colonization of opportunistic microflora in the experiment in-vitro alloy samples for the manufacture of clasp prostheses allows to objectively assess the level of bacterial contamination of dental materials and predict the effectiveness of hygienic measures removable dentures, which is especially important in patients with inflammatory periodontal diseases. Structural heterogeneity, low surface purity, polished cobalt-chromium alloy provide adhesion of microbial cells, thereby increasing the colonization of microflora on the surface of the material. A sample of the alloy based on gold, and cobalt-chromium alloy with electroplating showed identical results reduced sorption of microorganisms and good hygiene quality.

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Biofilm Formation on Dental Implant Biomaterials by Staphylococcus aureus Strains Isolated from Patients with Cystic Fibrosis

Materials ◽

10.3390/ma14082030 ◽

2021 ◽

Vol 14 (8) ◽

pp. 2030

Author(s):

Anna Minkiewicz-Zochniak ◽

Sylwia Jarzynka ◽

Agnieszka Iwańska ◽

Kamila Strom ◽

Bartłomiej Iwańczyk ◽

...

Keyword(s):

Cystic Fibrosis ◽

Staphylococcus Aureus ◽

Biofilm Formation ◽

Bacterial Biofilm ◽

Chromium Alloy ◽

Systemic Diseases ◽

Cobalt Chromium ◽

Bacterial Aggregation ◽

Cobalt Chromium Alloy

Implants made of ceramic and metallic elements, which are used in dentistry, may either promote or hinder the colonization and adhesion of bacteria to the surface of the biomaterial to varying degrees. The increased interest in the use of dental implants, especially in patients with chronic systemic diseases such as cystic fibrosis (CF), is caused by an increase in disease complications. In this study, we evaluated the differences in the in vitro biofilm formation on the surface of biomaterials commonly used in dentistry (Ti-6Al-4V, cobalt-chromium alloy (CoCr), and zirconia) by Staphylococcus aureus isolated from patients with CF. We demonstrated that S. aureus adherence and growth depends on the type of material used and its surface topography. Weaker bacterial biofilm formation was observed on zirconia surfaces compared to titanium and cobalt-chromium alloy surfaces. Moreover, scanning electron microscopy showed clear differences in bacterial aggregation, depending on the type of biomaterial used. Over the past several decades, S. aureus strains have developed several mechanisms of resistance, especially in patients on chronic antibiotic treatment such as CF. Therefore, the selection of an appropriate implant biomaterial with limited microorganism adhesion characteristics can affect the occurrence and progression of oral cavity infections, particularly in patients with chronic systemic diseases.

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Microrough Cobalt–Chromium Alloy Surfaces for Paclitaxel Delivery: Preparation, Characterization, and In Vitro Drug Release Studies

Langmuir ◽

10.1021/la301636z ◽

2012 ◽

Vol 28 (31) ◽

pp. 11511-11526 ◽

Cited By ~ 21

Author(s):

Susan Lancaster ◽

Sandeep Kakade ◽

Gopinath Mani

Keyword(s):

Drug Release ◽

Chromium Alloy ◽

Cobalt Chromium ◽

In Vitro Drug Release ◽

Release Studies ◽

Cobalt Chromium Alloy

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Covalently grafted BMP-7 peptide to reduce macrophage/monocyte activity: An in vitro study on cobalt chromium alloy

Biotechnology and Bioengineering ◽

10.1002/bit.24756 ◽

2012 ◽

Vol 110 (3) ◽

pp. 969-979 ◽

Cited By ~ 8

Author(s):

Hark Chuan Tan ◽

Chye Khoon Poh ◽

Yanli Cai ◽

Min Thun Soe ◽

Wilson Wang

Keyword(s):

In Vitro Study ◽

Vitro Study ◽

Chromium Alloy ◽

Cobalt Chromium ◽

Cobalt Chromium Alloy

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Rapid Prototyping forIn VitroKnee Rig Investigations of Prosthetized Knee Biomechanics: Comparison with Cobalt-Chromium Alloy Implant Material

BioMed Research International ◽

10.1155/2015/185142 ◽

2015 ◽

Vol 2015 ◽

pp. 1-9 ◽

Cited By ~ 5

Author(s):

Christian Schröder ◽

Arnd Steinbrück ◽

Tatjana Müller ◽

Matthias Woiczinski ◽

Yan Chevalier ◽

...

Keyword(s):

Sliding Friction ◽

Pressure Sensors ◽

Knee Kinematics ◽

Knee Biomechanics ◽

Chromium Alloy ◽

Cobalt Chromium ◽

Friction Coefficients ◽

Retropatellar Pressure ◽

Cobalt Chromium Alloy

Retropatellar complications after total knee arthroplasty (TKA) such as anterior knee pain and subluxations might be related to altered patellofemoral biomechanics, in particular to trochlear design and femorotibial joint positioning. A method was developed to test femorotibial and patellofemoral joint modifications separately with 3D-rapid prototyped components forin vitrotests, but material differences may further influence results. This pilot study aims at validating the use of prostheses made of photopolymerized rapid prototype material (RPM) by measuring the sliding friction with a ring-on-disc setup as well as knee kinematics and retropatellar pressure on a knee rig. Cobalt-chromium alloy (standard prosthesis material, SPM) prostheses served as validation standard. Friction coefficients between these materials and polytetrafluoroethylene (PTFE) were additionally tested as this latter material is commonly used to protect pressure sensors in experiments. No statistical differences were found between friction coefficients of both materials to PTFE. UHMWPE shows higher friction coefficient at low axial loads for RPM, a difference that disappears at higher load. No measurable statistical differences were found in knee kinematics and retropatellar pressure distribution. This suggests that using polymer prototypes may be a valid alternative to original components forin vitroTKA studies and future investigations on knee biomechanics.

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