scholarly journals Giant splenic cyst and solid pseudopapillary tumour of the pancreas managed with distal pancreatectomy and splenectomy

2020 ◽  
Vol 102 (4) ◽  
pp. e1-e3
Author(s):  
R Hajjar ◽  
M Plasse ◽  
F Vandenbroucke-Menu ◽  
F Schwenter ◽  
H Sebajang
Keyword(s):  
Distal Pancreatectomy ◽  
Histopathological Examination ◽  
Immunohistochemical Analysis ◽  
Young Female ◽  
Splenic Cyst ◽  
Large Size ◽  
Solid Pseudopapillary Tumour ◽  
Splenic Cysts ◽  
Pancreatic Tumour ◽  
The Right

Solid pseudopapillary tumours of the pancreas and giant splenic cysts are very rare entities, and their coexistence in a young female patient has not been previously reported in the literature. We present the case of a 27-year-old woman who presented with abdominal pain and two masses on abdominal imaging. A mass located in the right upper quadrant was biopsied, and histological and immunohistochemical analysis showed a solid pseudopapillary tumour of the pancreas. A giant cystic splenic lesion was also noted. The patient underwent a distal pancreatectomy and splenectomy in our referral centre. Margins were negative on histopathological examination. Negative surgical margins were achieved with distal pancreatectomy and splenectomy despite the large size of the pancreatic tumour. The management of solid pseudopapillary tumours of the pancreas is often challenging and the concomitant presence of a giant splenic cyst poses additional challenges to the surgical management of such tumours.

scholarly journals A rare gigantic primary epithelial cyst of spleen in an adolescent boy

2017 ◽  
Vol 4 (6) ◽  
pp. 2084
Author(s):  
Kiran George N. ◽  
Gayatri Balachandran ◽  
L. N. Mohan
Keyword(s):  
Histopathological Examination ◽  
Abdominal Distension ◽  
Splenic Cyst ◽  
Epithelial Cyst ◽  
Present Specimen ◽  
Left Flank ◽  
Left Hypochondrium ◽  
Midaxillary Line ◽  
Midclavicular Line ◽  
The Right

Cysts arising from spleen are a rare clinical entity, with their discovery usually being incidental. We present a case of the largest reported primary epithelial cyst of spleen. In present study a 16-year-old child presented with abdominal distension for 1 month associated with abdominal pain for 2 weeks. On examination, a mass was felt in the epigastrium, left hypochondrium and left flank, extending across from the right midclavicular line to the left midaxillary line, and extended inferiorly till 6cm caudal to umbilicus. CT abdomen revealed a unilocular cyst of 17x20x24cm arising from the spleen with a volume of 3700ml. Splenectomy was performed; intra-operatively there was a huge splenic cyst measuring 30x30x30cm. Histopathological examination was diagnostic of Primary congenital epithelial cyst of the spleen. Till date the largest congenital splenic cyst documented in literature is 20 cm × 13 cm × 21 cm, as reported by Valentina et al, in 2014. Present specimen bests this previous case considerably.

scholarly journals Giant Muscle Invasive Dermatofibroma Clinically Mimicking a Malignant Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Hideyuki Kinoshita ◽  
Takeshi Ishii ◽  
Hiroto Kamoda ◽  
Toshinori Tsukanishi ◽  
Sumihisa Orita ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Histopathological Examination ◽  
Present Report ◽  
Wide Resection ◽  
Large Size ◽  
Muscle Invasive ◽  
Muscle Invasion ◽  
The Right ◽  
Slow Growing ◽  
Muscle Invasive Tumor

Dermatofibromas are common benign fibrohistiocytic lesions, usually appearing as slow growing firm dermal nodules with a predilection for the extremities (mostly the lower legs). They are found mostly in middle-aged women and are usually smaller than 2 cm in diameter. Giant dermatofibromas exceeding 5 cm in diameter are rare. In recent years, reports have suggested a relationship between the primary size of dermatofibromas and rates of local recurrence and metastases after surgery. This relationship is however debated. The present report describes the case of a giant muscle invasive tumor in a 51-year-old female patient who presented with a large ulcerated mass in the right upper arm. The tumor appeared clinically malignant, measuring approximately 12 cm × 6 cm in size, with ulceration and invasion of surrounding muscle. Wide resection of the tumor was performed with myocutaneous flap-plasty. Histopathological examination showed evidence of a dermatofibroma. No recurrence, metastases, or other complications were noted at 5 years after surgery. The present case demonstrates that although dermatofibromas are essentially benign, they may present with atypical features including large size, ulceration, and muscle invasion, clinically mimicking malignant tumors.

scholarly journals Massive splenic epidermoid cyst in a child treated with laparoscopic partial splenectomy – case report and review of literature

2018 ◽  
Vol 28 (1) ◽  
pp. 61-64
Author(s):  
Lasitha B Samarakoon ◽  
Sharon Si Min Goh ◽  
Yee Ling Cheong ◽  
Lin Yin Ong
Keyword(s):  
Epidermoid Cyst ◽  
Female Child ◽  
Young Female ◽  
Traumatic Rupture ◽  
Lower Pole ◽  
Review Of Literature ◽  
Cyst Excision ◽  
Large Size ◽  
Splenic Cysts ◽  
Persistent Abdominal Pain

Splenic cysts are extremely rare. We present the case of a young female child who presented with a massive splenic cyst arising from the lower pole of the spleen. We offered surgical intervention in view of persistent abdominal pain and the large size of the cyst, which was predisposing it to traumatic rupture and restricting the child’s normal activities. Cyst excision with splenic preservation was successfully achieved via a laparoscopic lower pole splenectomy. Histology confirmed a benign epidermoid cyst. The case presentation is followed by a brief review of literature.

Laparoscopic spleen-preserving dome resection for a giant primary epithelial splenic cyst

2021 ◽  
Vol 14 (9) ◽  
pp. e245635
Author(s):  
Neil Robert Lowrie ◽  
Monica Jane Londahl ◽  
Konrad Klaus Richter
Keyword(s):  
Laparoscopic Surgery ◽  
Female Patient ◽  
Current Literature ◽  
Young Female ◽  
Splenic Cyst ◽  
Surgical Practice ◽  
Spleen Preserving ◽  
Splenic Cysts ◽  
Surgical Technical ◽  
Epithelial Cysts

Non-parasitic splenic cysts are rare and are seldom diagnosed outside the paediatric surgical practice. Giant true primary epithelial cysts greater than 14 cm in diameter are even rarer. Laparoscopic surgery is preferable; however, bleeding, splenectomy and recurrence are recognised risks. Here, we report a young female patient with a 21 cm symptomatic primary splenic cyst. The patient underwent a spleen-preserving laparoscopy and was followed up for 2 years when she had an MRI of the abdomen. Surgical, technical and perioperative treatment aspects are discussed here, in the context of the current literature.

scholarly journals Total Splenectomy due to an Unexpected “Complication” after Successful Extended Laparoscopic Partial Decapsulation of a Giant Epidermoid Splenic Cyst: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Michail Pitiakoudis ◽  
Petros Zezos ◽  
Anastasia Oikonomou ◽  
Prodromos Laftsidis ◽  
Georgios Kouklakis ◽  
...  
Keyword(s):  
Young Female ◽  
Splenic Cyst ◽  
Epithelial Lining ◽  
Abdominal Ct ◽  
Spleen Preserving ◽  
Splenic Cysts ◽  
Surgical Options ◽  
Total Splenectomy ◽  
Splenic Vessels ◽  
Laparoscopic Techniques

Splenic cysts are rare entities and are classified as true cysts or pseudocysts based on the presence of an epithelial lining. Congenital nonparasitic true cysts can be epidermoid, dermoid, or endodermoid, present at a young age, and are commonly located in the upper pole of the spleen. Surgical treatment is recommended for symptomatic, large (more than 5 cm), or complicated cysts. Depending on cyst number, location, relation to hilus, and the major splenic vessels, the surgical options include aspiration, marsupialization, cystectomy, partial cystectomy (decapsulation), and partial or complete splenectomy. Laparoscopic techniques have now become the standard approach for many conditions, including the splenic cysts, with emphasis on the spleen-preserving minimally invasive operations. We present the successful extended partial laparoscopic decapsulation of a giant epidermoid splenic cyst in a young female patient that, although asymptomatic, was unfortunately followed by complete splenectomy five days later due to a misinterpreted abdominal CT suggesting splenic postoperative ischemia.

scholarly journals Primary Cutaneous Mucinous Carcinoma Presenting as an Unusually Large Lesion - A Rare Case Report

2021 ◽  
Vol 10 (34) ◽  
pp. 2939-2941
Author(s):  
Jiby Soosen Ninan ◽  
Ajithakumari K. ◽  
Tony Mathew
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Mucinous Carcinoma ◽  
Malignant Tumour ◽  
Large Size ◽  
Rare Case Report ◽  
Eccrine Carcinoma ◽  
One Year ◽  
The Right ◽  
Adnexal Tumour

Primary cutaneous mucinous carcinoma (PCMC) also known as primary mucinous carcinoma of the skin (PMCS) or primary mucinous eccrine carcinoma (PMEC) is a rare malignant adnexal tumour of eccrine origin. Many visceral mucinous carcinomas especially of the breast and gastrointestinal tract can metastasize to the skin mimicking PCMC. Hence it is very important to rule out metastatic mucinous carcinomas before making a diagnosis of PCMC. Usually, PCMC presents as a slowgrowing tumour of considerably smaller size compared to our case. The large size and shorter duration are the key features of this case report. Here we report an unusually large-sized rare malignant tumour of skin appendage. Our patient was a 54-year-old lady who presented with progressive swelling of one year duration in the right frontoparietal area. Ultrasonography showed an ill-defined lesion in the subcutaneous plane with multiple cystic spaces within it. No bone involvement was noted. The excised lesion measured 13 x 7 x 2 cms and was diagnosed as primary cutaneous mucinous carcinoma on histopathological examination. The possibility of cutaneous secondaries from elsewhere was ruled out by detailed clinical and radiological investigations. The case is reported considering the unusually bigger size and shorter duration of this rare entity.

scholarly journals Primary Pleural Angiosarcoma in a 63-Year-Old Gentleman

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ahmed Abu-Zaid ◽  
Shamayel Mohammed
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Histopathological Examination ◽  
Case Reports ◽  
Immunohistochemical Analysis ◽  
Whole Body ◽  
Cytologic Examination ◽  
Ct Guided ◽  
Positron Emission ◽  
The Right

Primary pleural angiosarcomas are extremely rare. As of 2010, only around 50 case reports have been documented in the literature. Herein, we report the case of a 63-year-old gentleman who presented with a 3-month history of right-sided chest pain, dyspnea, and hemoptysis. Chest X-ray showed bilateral pleural effusion with partial bibasilar atelectasis. Ultrasound-guided thoracocentesis showed bloody and exudative pleural fluid. Cytologic examination was negative for malignant cells. An abdominal contrast-enhanced computed tomography (CT) scan showed two right diaphragmatic pleural masses. Whole-body positron emission tomography/computed tomography (PET/CT) scan showed two hypermetabolic fluorodeoxyglucose- (FDG-) avid lesions involving the right diaphragmatic pleura. CT-guided needle-core biopsy was performed and histopathological examination showed neoplastic cells growing mainly in sheets with focal areas suggestive of vascular spaces lined by cytologically malignant epithelioid cells. Immunohistochemical analysis showed strong positivity for vimentin, CD31, CD68, and Fli-1 markers. The overall pathological and immunohistochemical features supported the diagnosis of epithelioid angiosarcoma. The patient was scheduled for surgery in three weeks. Unfortunately, the patient died after one week after discharge secondary to pulseless ventricular tachycardia arrest followed by asystole. Moreover, we also present a brief literature review on pleural angiosarcoma.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Successful Control of a Co-Infection Caused by Candida albicans and Pseudomonas aeruginosa in Keratitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Debarati Paul ◽  
Suman Saha ◽  
Neelam Singh ◽  
Jayansgu Sengupta ◽  
Santi M. Mandal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Candida Albicans ◽  
Histopathological Examination ◽  
Specific Interaction ◽  
Major Threat ◽  
Effective Combination ◽  
Male Farmer ◽  
Successful Control ◽  
The Right ◽  
Corneal Button

Introduction: Nowadays, co-infection by interspecific organisms is major threat in infection control. To identify the effective combination of drugs to control the keratitis caused by Candida albicans with Pseudomonas aeruginosa are attributed in this study. Materilas and Methods: The patient of a 47 years old male farmer with infection in the right eye which showed redness and watering was treated with fortified cefazolin and fortified tobramycin before referral. No pigmentation or vascularisation was noted. The excised corneal button was also subjected to microbiological and histopathological examination. Results: A rare case of keratitis caused by co-infection of Candida albicans with Pseudomonas aeruginosa was identified. Results confirmed the inter-specific interaction of the two microorganisms. Conclusion: Cases of co-infection by Candida and Pseudomonas are not abundantly reported and difficult to treat. In this case, treatment involved Amphotercin-B and ciprofloxacin, effectively eradicated the infection. This therapy may be successfully implied for such cases of co-infection in future.

Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

2019 ◽  
Vol 12 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Dheyauldeen Shabeeb ◽  
Masoud Najafi ◽  
Ahmed Eleojo Musa ◽  
Mansoor Keshavarz ◽  
Alireza Shirazi ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Histopathological Examination ◽  
Radical Scavenging ◽  
Limiting Factor ◽  
Skin Damage ◽  
Exposed Skin ◽  
Male Wistar Rats ◽  
Time Periods ◽  
Skin Damages ◽  
The Right

Background:Radiotherapy is one of the treatment methods for cancers using ionizing radiations. About 70% of cancer patients undergo radiotherapy. Radiation effect on the skin is one of the main complications of radiotherapy and dose limiting factor. To ameliorate this complication, we used melatonin as a radioprotective agent due to its antioxidant and anti-inflammatory effects, free radical scavenging, improving overall survival after irradiation as well as minimizing the degree of DNA damage and frequency of chromosomal abrasions.Methods:Sixty male Wistar rats were randomly assigned to 4 groups: control (C), melatonin (M), radiation (R) and melatonin + radiation (MR). A single dose of 30 Gy gamma radiation was exposed to the right hind legs of the rats while 40 mg/ml of melatonin was administered 30 minutes before irradiation and 2 mg/ml once daily in the afternoon for one month till the date of rat’s sacrifice. Five rats from each group were sacrificed 4, 12 and 20 weeks after irradiation. Afterwards, their exposed skin tissues were examined histologically and biochemically.Results:In biochemical analysis, we found that malondialdehyde (MDA) levels significantly increased in R group and decreased significantly in M and MR groups after 4, 12, and 20 weeks, whereas catalase (CAT) and superoxide dismutase (SOD) activities decreased in the R group and increased in M and MR groups during the same time periods compared with the C group (p<0.05). Histopathological examination found there were statistically significant differences between R group compared with the C and M groups for the three different time periods (p<0.005, p<0.004 and p<0.004) respectively, while R group differed significantly with MR group (p<0.013). No significant differences were observed between C and M compared with MR group (p>0.05) at 4 and 20 weeks except for inflammation and hair follicle atrophy, while there were significant effects at 12 weeks (p<0.05).Conclusion:Melatonin can be successfully used for the prevention and treatment of radiation-induced skin injury. We recommend the use of melatonin in optimal and safe doses. These doses should be administered over a long period of time for effective radioprotection and amelioration of skin damages as well as improving the therapeutic ratio of radiotherapy.

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