scholarly journals Telangiectatic Osteosarcoma in a Young Child – A Case Report and Review of the Literature

2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Gracelin Jeyarani ◽  
Dhaarani Jayaraman ◽  
Gopinath Menon ◽  
JK Giriraj Harshavardhaan ◽  
S Rajendiran ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Tumors ◽  
Proximal Humerus ◽  
Lytic Lesion ◽  
Wide Resection ◽  
Left Shoulder ◽  
Limb Salvage Surgery ◽  
Age Group ◽  
Osteolytic Lesions ◽  
Telangiectatic Osteosarcoma

Introduction: Osteosarcoma (OS) is one of the most common primary malignant bone tumors in children and adolescents. OS incidence varies significantly with age and peak incidence is in adolescent age group. Telangiectatic osteosarcoma (TOS) is an unusual variant of OS, forming 3–10% of all OSs. Only few case reports of this rare variant of OS are described in the literature. Case Report: We report a 6-year-girl who presented with fracture of the left proximal humerus after a trivial trauma. X-ray left shoulder showed osteolytic lesions in the left proximal humerus with fracture of proximal humerus. Open biopsy from the left proximal humerus osteolytic lesion suggested clusters of highly atypical cells like osteoid material and focal areas of hemorrhage and necrosis suggestive of TOS. The child was started on chemotherapy followed by limb-salvage surgery with wide resection of the tumor in the left proximal humerus. She completed her adjuvant chemotherapy and is currently doing well for the past 4 years. Conclusion: OS occurs more frequently in adolescents around the knee in the metaphyses. The most common histologic type is osteoblastic/fibroblastic or chondroblastic type. Very few cases have been reported in <5 years age group and it’s relatively rare in 5–10-year-old children. Rare histologic variants, especially telangiectatic variant, are more common in younger children and occur more in upper limbs. Imaging reveals mainly osteolytic lesions, unlike in conventional OS. This case highlights the utmost role of histopathology in the diagnosis of the bone tumors which would guide the management appropriately. Keywords: Osteosarcoma, pathological fracture, expansile lytic lesion, telangiectatic osteosarcoma.

scholarly journals A Massive Chondroblastoma in the Proximal Humerus Simulating Malignant Bone Tumors

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ichiro Tonogai ◽  
Mitsuhiko Takahashi ◽  
Hiroaki Manabe ◽  
Toshihiko Nishisho ◽  
Seiji Iwamoto ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Proximal Humerus ◽  
Histopathological Examination ◽  
Extreme Case ◽  
Transcatheter Embolization ◽  
Bone Neoplasm ◽  
Lytic Lesion ◽  
Reconstructive Procedure ◽  
Malignant Bone Tumors ◽  
Local Destruction

Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion in the epiphysis of long bones. We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl. It was difficult to differentiate using imaging information the lesion from malignant bone tumors such as osteosarcoma. Histopathological examination from biopsy proved chondroblastoma. The tumor was resected after preoperative transcatheter embolization. Reconstructive procedure for the proximal humerus was not performed due to the local destruction. The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions and histopathological understandings for this lesion.

scholarly journals Primary Angiosarcoma of Humerus – A Case Report and Literature Review

2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Madhan Jeyaraman ◽  
Sathish Muthu ◽  
Manoj Prabhakar ◽  
Naveen Jeyaraman ◽  
Garima Agarwal ◽  
...  
Keyword(s):  
Case Report ◽  
Proximal Humerus ◽  
Multimodality Imaging ◽  
Plain Radiograph ◽  
Treatment Protocol ◽  
Lytic Lesion ◽  
Vascular Tumors ◽  
Tissue Mass ◽  
History Of ◽  
The Right

Introduction: Osseous angiosarcoma is a very rare tumor of bone with aggressive behavior, propensity for recurrences, and distant metastasis. The etiology of osseous angiosarcoma is uncertain; however, specific risk factors have been recognized. The diagnosis of angiosarcoma of bone demands multimodality imaging in conjunction with histopathological and vascular marker evaluation to aptly differentiate them from other vascular tumors. Treatment of osseous angiosarcoma remains controversial. Case Report: A 53-year-old male presented with pain and swelling of the right upper 1/3rd of the arm following heaviness while lifting weight for 3 months. He had a history of significant weight loss and appetite with no history of inciting trauma or irradiation in the past. On examination, a diffuse swelling was noted in the right shoulder and right scapular aspect with varied consistency and ill-defined borders and margins. The skin over the swelling was stretched and shiny with dilated engorged veins over it. The plain radiograph of the right shoulder with humerus revealed a large expansile lytic soft-tissue mass in the right proximal humerus with a wide zone of transition without sclerotic margins. Magnetic resonance imaging showed T1 hypointense, T2/PDFS hyperintense large well-defined expansile lytic lesion with multi-loculated cysts, and multiple blood-fluid levels involving right proximal humerus. The patient underwent an incisional biopsy which exhibited angiosarcoma of the humerus. The patient was treated with six cycles of chemotherapy with a mesna, doxorubicin, ifosfamide, and dacarbazine regimen. The patient was still under follow-up. Conclusion: Being a rare clinical entity, controversy exists in angiosarcoma of humerus regarding its etiology and recommended management protocols. Histopathology and immunohistochemistry remain the gold standard in differentiating osseous angiosarcoma from other osseous vascular tumors. The treatment protocol has to be standardized to

scholarly journals A Case Report of Limb Salvage Surgery with Scapular Flap for Osteosarcoma of Proximal Humerus.

2003 ◽  
Vol 52 (4) ◽  
pp. 738-741
Author(s):  
Masakazu Murata ◽  
Kenji Kumagai ◽  
Masahiko Suzuki ◽  
Sou Morooka ◽  
Hiroyuki Shindo ◽  
...  
Keyword(s):  
Case Report ◽  
Limb Salvage ◽  
Proximal Humerus ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Scapular Flap

Atypical Osteoid Osteoma of sacral region in pediatric age group: a case report

2017 ◽  
pp. 28-31
Author(s):  
Shashi Sharma ◽  
Sakshi Dewan ◽  
Naveen Bhardwaj ◽  
Mir Aziz ◽  
Shilpa Singh ◽  
...  
Keyword(s):  
Case Report ◽  
Osteoid Osteoma ◽  
Age Group ◽  
Pediatric Age ◽  
Sacral Region ◽  
Pediatric Age Group ◽  
Group A

Healing Of A Large Osteolytic Mandibular Lesion – A Case Report

2018 ◽  
Author(s):  
Ingrid Różyło-Kalinowskav ◽  
Karolina Sidor
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Surgical Approach ◽  
Orthodontic Treatment ◽  
Incidental Finding ◽  
Osteolytic Lesion ◽  
Panoramic Radiograph ◽  
Endodontic Treatment ◽  
Osteolytic Lesions

The purpose of this article was to present a case report of 11–year old female patient with a large osteolytic mandibular lesion which healed after endodontic treatment. The patient was referred for radio diagnostics due to an incidental finding of a large osteolytic lesion of the area of the left lower first and second premolars in the panoramic radiograph taken before orthodontic treatment. CBCT was performed and the patient asked to have teeth 33-35 treated by endodontics before surgery. The patient missed the surgical appointment and when she reappeared several months later, the lesion showed signs of healing thus surgery were aborted. The presented case testifies to the observation that even large osteolytic lesions can heal after endodontic treatment without surgical approach.

Limb salvage surgery for malignant bone tumors of the extremities in children and adolescents

2009 ◽  
Vol 8 (11) ◽  
pp. 631-637 ◽  
Author(s):  
Zhen Wang ◽  
Zheng Guo ◽  
Xiangdong Li ◽  
Luyu Huang ◽  
Qiang Ji ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Limb Salvage ◽  
Bone Tumors ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Malignant Bone Tumors

scholarly journals Unifocal Granuloma of Femur due to Langerhans' Cell Histiocytosis: A Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Harpreet Singh ◽  
Satnam Kaur ◽  
P. Yuvarajan ◽  
Nishant Jain ◽  
Lalit Maini
Keyword(s):  
Case Report ◽  
Clinical Data ◽  
Case History ◽  
Langerhans Cell Histiocytosis ◽  
Eosinophilic Granuloma ◽  
Pediatric Population ◽  
Langerhans Cell ◽  
Long Bones ◽  
Review Of The Literature ◽  
Osteolytic Lesions

The radiological diagnosis of osteolytic lesions of the long bones in pediatric population constitutes a challenge when the case history and clinical data are uncharacteristic. We believe that the description of few clinically and histologically proven cases to verify the existence of radiological signs useful for diagnosis may be of interest. Here, we describe a case of Langerhans' cell histiocytosis (LCH) presenting as unifocal eosinophilic granuloma of femur along with a brief review of the literature.

scholarly journals Fracture of Proximal Humerus & Shaft Managed With Closed Reduction & External Fixation by Joshi External Stabilisation System (Jess) – A Case Report

2018 ◽  
Vol 5 (1) ◽  
pp. 54-58
Author(s):  
Prakriti Raj Kandel ◽  
Rajiv Baral ◽  
Abhishek Kumar Thakur ◽  
Gyaneshwar Prasad Singh ◽  
Laxmi Pathak
Keyword(s):  
External Fixation ◽  
Closed Reduction ◽  
Proximal Humerus ◽  
Road Traffic ◽  
Skin Grafting ◽  
Shaft Fracture ◽  
Left Shoulder ◽  
Medical Sciences ◽  
Lacerated Wound ◽  
Fracture Of Proximal Humerus

We are presenting a case of proximal humerus& shaft fracture in a 50 year old female. She sustained injury on her left upper limb in a road traffic accident. It was managed with closed reduction & external fixation by Joshi External Stabilisation System (JESS). Lacerated wound over her left shoulder & arm region was managed with skin grafting. The post-operative period was uneventful. Journal of Universal College of Medical Sciences (2017) Vol.05 No.01 Issue 15, Page: 54-58

scholarly journals Excess of Plasma Cells with Pseudo-Gaucher Cells in a Case of Tuberculosis - A Case Report

2013 ◽  
Vol 9 (2) ◽  
pp. 30-32
Author(s):  
A Palta ◽  
P Dhiman ◽  
J Ram
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Inflammatory Reaction ◽  
Lung Diseases ◽  
Plasma Cells ◽  
Bone Marrow Examination ◽  
Lytic Lesion ◽  
Rare Finding ◽  
Antitubercular Treatment ◽  
Chronic Inflammatory Reaction

This report describes a case of 50 year old woman fever and bony pains with lytic lesion in skull. A polyclonal band was seen in γregion on serum electrophoresis. Bone marrow examination showed excess of plasma cells along with many Pseudo- Gaucher cells. The diagnosis of chronic inflammatory reaction was made. Although stain for AFB was negative, the patient responded to antitubercular treatment. The presence of pseudo-gaucher cells along with plasmacytosis is a rare finding in tuberculosis. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2012; IX(2) 30-32 DOI: http://dx.doi.org/10.3126/saarctb.v9i2.7976

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