scholarly journals Chromatographically purified Vi-capsular polysaccharide antigen for vaccination against Typhoid fever

1998 ◽  
pp. 240
Author(s):  
I.V. Ankudinov ◽  
M.E. Golovina ◽  
V.L. L'vov ◽  
N.P. Vaneeva ◽  
I.C. Verner ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Capsular Polysaccharide ◽  
Polysaccharide Antigen ◽  
Vi Capsular Polysaccharide

scholarly journals Whole-Genome Sequences of Two Salmonella enterica Serovar Dublin Strains That Harbor the viaA, viaB, and ompB Loci of the Vi Antigen

2019 ◽  
Vol 8 (14) ◽  
Author(s):  
Manal Mohammed ◽  
Marie-Leone Vignaud ◽  
Sabrina Cadel-Six
Keyword(s):  
Salmonella Enterica ◽  
Capsular Polysaccharide ◽  
Raw Milk ◽  
Genome Sequences ◽  
Polysaccharide Antigen ◽  
Content Type ◽  
Vi Capsular Polysaccharide ◽  
Raw Milk Cheese ◽  
Salmonella Enterica Serovar Dublin ◽  
Vi Antigen

Here, we report the genome sequences of two Salmonella enterica serovar Dublin strains, 03EB8736SAL and 03EB8994SAL, isolated from raw-milk cheese and milk filtrate, respectively. Analysis of the draft genomes of the two isolates reveals the presence of the viaA, viaB, and ompB loci of the Vi capsular polysaccharide antigen (Vi antigen).

Prevention of Typhoid Fever in Nepal with the VI Capsular Polysaccharide ofSalmonella Typhi

1987 ◽  
Vol 317 (18) ◽  
pp. 1101-1104 ◽  
Author(s):  
Iswar L. Acharya ◽  
Charles U. Lowe ◽  
Rita Thapa ◽  
Vijay L. Gurubacharya ◽  
M.B. Shrestha ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Capsular Polysaccharide ◽  
Vi Capsular Polysaccharide

PROTECTIVE ACTIVITY OF VI CAPSULAR POLYSACCHARIDE VACCINE AGAINST TYPHOID FEVER

The Lancet ◽  
1987 ◽  
Vol 330 (8569) ◽  
pp. 1165-1169 ◽  
Author(s):  
KeithP. Klugman ◽  
HendrikJ. Koornhof ◽  
Rachel Schneerson ◽  
Michel Cadoz ◽  
IanT. Gilbertson ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Capsular Polysaccharide ◽  
Polysaccharide Vaccine ◽  
Protective Activity ◽  
Vi Capsular Polysaccharide

scholarly journals Characterization of Citrobacter sp. line 328 as a source of Vi for a Vi-CRM197 glycoconjugate vaccine against Salmonella Typhi

2012 ◽  
Vol 6 (11) ◽  
pp. 763-773 ◽  
Author(s):  
Simona Rondini ◽  
Francesca Micoli ◽  
Luisa Lanzilao ◽  
Ivan Pisoni ◽  
Vito Di Cioccio ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Capsular Polysaccharide ◽  
Salmonella Typhi ◽  
Defined Medium ◽  
Industrial Scale ◽  
Scale Production ◽  
Populations At Risk ◽  
Vi Capsular Polysaccharide ◽  
High Yields ◽  
Antibody Levels

Introduction: Salmonella enterica serovar Typhi is the causative agent of typhoid fever with over 22 million cases and over 200,000 deaths reported annually. A vaccine is much needed for use in young children and the Novartis Vaccines Institute for Global Health (NVGH) is developing a conjugate vaccine which targets S. Typhi Vi capsular polysaccharide. Methodology: Here we describe a method suitable for industrial scale production of the Vi antigen based on expression by a Citrobacter line. We optimized the production of Vi by selecting a suitable Citrobacter strain (Citrobacter 328) that yields high and stable expression of Vi in chemically defined medium under industrial-scale fermentation conditions. Results: Vi-CRM197 made using Vi from Citrobacter 328 elicited high anti-Vi antibody levels in mice and rabbits. Conclusions: Citrobacter 328 is a suitable strain for production of Vi for conjugate anti-Typhi vaccines. Being a BSL-1 organism, which grows in defined medium and stably produces high yields of Vi, it offers excellent potential for safe production of inexpensive vaccines for populations at risk of typhoid fever.

Anodic stripping voltammetry of anti-Vi antibody functionalized CdTe quantum dots for the specific monitoring of Salmonella enterica serovar Typhi

RSC Advances ◽  
2015 ◽  
Vol 5 (107) ◽  
pp. 88234-88240 ◽  
Author(s):  
Satish K. Pandey ◽  
Praveen Rishi ◽  
C. Raman Suri ◽  
Aaydha C. Vinayaka
Keyword(s):  
Quantum Dots ◽  
Capsular Polysaccharide ◽  
Anodic Stripping Voltammetry ◽  
Stripping Voltammetry ◽  
Cdte Quantum Dots ◽  
Salmonella Enterica Serovar Typhi ◽  
Novel Approach ◽  
Anodic Stripping ◽  
Vi Capsular Polysaccharide ◽  
Insight Into

CdTe QD based stripping voltammetry for Vi capsular polysaccharide detection. The technique has provided an insight into the competence of CdTe QD and GNP immuno-conjugates. This is a novel approach to characterize the efficiency of immuno-conjugates of QDs and GNPs.

Sign in / Sign up

Export Citation Format

Share Document