Redefining the HER2 Oncobiomarker: A Relevant Case Report

Abstract Purpose: This study aimed to summarize the general history, physical exam findings, confirmation test, and treatment of a patient with juvenile ocular myasthenia gravis. Research Methodology: This article is a pediatric RSUD Abdoel Moeloek Lampung case report in April 2021. The subject of the case is a 3-year-old girl who is hospitalized in the hospital ward with juvenile ocular myasthenia gravis. Result: A 3-year-old girl, an inpatient in the Pediatric Ward, RSUD Abdoel Moeloek Lampung, with complaints of decreased left upper eyelid since three months ago. On physical examination, there was ptosis of the left superior palpebra. Prostigmine test was performed on day 2 of treatment in patients with positive test results. The patient was clinically diagnosed with “Juvenile Ocular Myasthenia Gravis.” Management of the patient during treatment was the injection of methylprednisolone 10 mg/12 hours and neostigmine orally 2.5 mg/8 hours. Limitations: This case report is limited to juvenile ocular myasthenia gravis cases with a scarce number of cases and rare cases in children. Contribution: This case report can be helpful in medical education or used as a reference in making relevant case reports and can be applied in the hospital area when there are cases of juvenile ocular myasthenia gravis.

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Public Health Automated Case Event Reporting (PACER) Platform for Enhancing Electronic Laboratory Reports with Clinical Data (Preprint)

10.2196/preprints.26388 ◽

2020 ◽

Author(s):

Ninad Mishra ◽

Jon Duke ◽

Saugat Karki ◽

Myung Choi ◽

Michael Riley ◽

...

Keyword(s):

Public Health ◽

Case Report ◽

Positive Test ◽

Health Reporting ◽

Test Results ◽

Complete Case ◽

Event Reporting ◽

Additional Information ◽

Public Health Reporting ◽

Relevant Case

BACKGROUND Public health reporting is the cornerstone of public health practice that inform the prevention and control strategies. Over the years, public health reporting has advanced to automated electronic methods but have been fraught with complex nuances in clinical and public health workflows, data and messaging standards, and efficient process and technology tools. There is a need to leverage advances made in the past to implement an architecture that facilitates timely and complete public health reporting with relevant case-related information that have previously not easily been available to the public health community. OBJECTIVE Positive test results of notifiable conditions are reported as electronic laboratory report (ELR) from laboratories. ELR is a reliable method for reporting cases to public health authorities but contains very limited data. We have designed Public Health Automated Case Event Reporting (PACER) platform that leverages existing ELR infrastructure. PACER is a Fast Health Interoperability Resources (FHIR) based system that queries the electronic health record (EHR) from where the laboratory test was requested, to extract expanded information about the case such as additional demographics, diagnoses, and treatment data. METHODS Incoming ELR to a public health department were used as the trigger for a FHIR-based query. Predetermined queries were translated to Clinical Quality Language (CQL) logics. Within the PACER environment, these CQL logical statements were managed and evaluated against the providers’ FHIR servers. These predetermined logics were filtered and only data relevant to that episode of the condition were extracted and sent to public health as an electronic case report (eCR). We evaluated this architecture by examining the completeness of additional information in the eCR such as patient demographics, medications, symptoms, and diagnoses. This additional information is crucial in understanding disease epidemiology but existing eCR and ELR architectures do not report them, therefore, we used the completeness of these data fields as the metrics to gauge extent of enriching notifiable condition case reports. RESULTS During an eight-week study period, we identified 117 positive test results of chlamydia. PACER successfully created an eCR for all 117 patients. PACER extracted demographics, medications, syPACER deployed in conjunction with ELRs can enhance public health case reporting with additional relevant data. The architecture is modular in design, allowing it to be used for any reportable condition, including evolving outbreaks. PACER allows for an enhanced and complete case report that contains relevant case information that helps us to better understand the epidemiology of the disease.mptoms, and diagnoses in 99%, 73%, 71%, and 65% of the cases respectively. CONCLUSIONS PACER deployed in conjunction with ELRs can enhance public health case reporting with additional relevant data. The architecture is modular in design, allowing it to be used for any reportable condition, including evolving outbreaks. PACER allows for an enhanced and complete case report that contains relevant case information that helps us to better understand the epidemiology of the disease.

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Arthroscopic excision of heterotopic calcification in a chronic rectus femoris origin injury: a case report

Annals of The Royal College of Surgeons of England ◽

10.1308/003588412x13171221589333 ◽

2012 ◽

Vol 94 (3) ◽

pp. e129-e131 ◽

Cited By ~ 5

Author(s):

M El-Husseiny ◽

M Sukeik ◽

FS Haddad

Keyword(s):

Chronic Pain ◽

Case Report ◽

Conservative Treatment ◽

Acute Phase ◽

Surgical Repair ◽

Rectus Femoris ◽

Favourable Outcome ◽

Heterotopic Calcification ◽

Arthroscopic Excision ◽

Relevant Case

Rectus femoris origin injuries in adult athletes are uncommon. In the acute phase, conservative treatment seems to have a favourable outcome, with surgical repair reserved for unsuccessful cases only. However, a group of patients may develop chronic pain and disability after recovery from the acute phase due to heterotopic calcification occurring at the site of injury. Open and arthroscopic excision of such calcifications has been described in the literature although arthroscopic excision of large calcified lesions in the rectus femoris has not been reported previously. A relevant case is presented and discussed.

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Lethal hepatotoxicity following 5-fluorouracil/cisplatin chemotherapy: a relevant case report

Personalized Medicine ◽

10.2217/pme-2016-0085 ◽

2017 ◽

Vol 14 (3) ◽

pp. 197-201 ◽

Cited By ~ 3

Author(s):

Aline Hajj ◽

Marwan Ghosn ◽

Diane Mourad ◽

Khalil Hojaiban ◽

Perla Mousallem ◽

...

Keyword(s):

Case Report ◽

Relevant Case

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Misophonia: An Evidence-Based Case Report

American Journal of Audiology ◽

10.1044/2020_aja-19-00111 ◽

2020 ◽

Vol 29 (4) ◽

pp. 685-690

Author(s):

C. S. Vanaja ◽

Miriam Soni Abigail

Keyword(s):

Quality Of Life ◽

Case Report ◽

Case History ◽

Pure Tone ◽

Physiological Responses ◽

Evidence Based ◽

Management Option ◽

Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

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Intensive Stuttering Therapy With Telepractice Follow-up: A Case Study

Perspectives on Fluency and Fluency Disorders ◽

10.1044/ffd21.1.11 ◽

2011 ◽

Vol 21 (1) ◽

pp. 11-21 ◽

Cited By ~ 2

Author(s):

Farzan Irani ◽

Rodney Gabel

Keyword(s):

Case Report ◽

Therapeutic Intervention ◽

Intensive Therapy ◽

Positive Outcome ◽

Eclectic Approach

This case report describes the positive outcome of a therapeutic intervention that integrated an intensive, residential component with follow-up telepractice for a 21 year old male who stutters. This therapy utilized an eclectic approach to intensive therapy in conjunction with a 12-month follow-up via video telepractice. The results indicated that the client benefited from the program as demonstrated by a reduction in percent stuttered syllables, a reduction in stuttering severity, and a change in attitudes and feelings related to stuttering and speaking.

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A Tape-Recorded Therapy Method for Stutterers: A Case Report

Journal of Speech and Hearing Disorders ◽

10.1044/jshd.3502.188 ◽

1970 ◽

Vol 35 (2) ◽

pp. 188-193 ◽

Cited By ~ 4

Author(s):

Maryann Peins ◽

Bernard S. Lee ◽

W. Edward McGough

Keyword(s):

Case Report

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The Use of Real-Time Visual Displays of Speech in the Training of a Profoundly Deaf, Nonspeaking Child: A Case Report

Journal of Speech and Hearing Disorders ◽

10.1044/jshd.3603.397 ◽

1971 ◽

Vol 36 (3) ◽

pp. 397-409 ◽

Cited By ~ 10

Author(s):

Rachel E. Stark

Keyword(s):

Case Report ◽

Real Time ◽

Speech Production ◽

Behavior Problem ◽

Deaf Children ◽

Developmental Sequence ◽

Visual Displays ◽

Individual Instruction ◽

Academic Record ◽

Extract Information

Real-time amplitude contour and spectral displays were used in teaching speech production skills to a profoundly deaf, nonspeaking boy. This child had a visual attention problem, a behavior problem, and a poor academic record. In individual instruction, he was first taught to produce features of speech, for example, friction, nasal, and stop, which are present in vocalizations of 6- to 9-month-old infants, and then to combine these features in syllables and words. He made progress in speech, although sign language and finger spelling were taught at the same time. Speech production skills were retained after instruction was terminated. The results suggest that deaf children are able to extract information about the features of speech from visual displays, and that a developmental sequence should be followed as far as possible in teaching speech production skills to them.

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Erratum: Recurrent Laryngeal Nerve Dissection

Journal of Speech and Hearing Disorders ◽

10.1044/jshd.4503.427b ◽

1980 ◽

Vol 45 (3) ◽

Author(s):

Frank B. Wilson ◽

D. J. Oldring ◽

Kathleen Mueller

Keyword(s):

Case Report ◽

Recurrent Laryngeal Nerve ◽

Laryngeal Nerve ◽

Long Period ◽

Initial Surgery

On page 112 of the report by Wilson, Oldring, and Mueller ("Recurrent Laryngeal Nerve Dissection: A Case Report Involving Return of Spastic Dysphonia after Initial Surgery," pp. 112-118), the paraphrase from Cooper (1971), "if the patients are carefully selected and are willing to remain in therapy for a long period of time," was inadvertantly put in quotation marks.

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