Role of Fluoxetine in Anorexia Nervosa

2003 ◽  
Vol 37 (6) ◽  
pp. 890-892 ◽  
Author(s):  
Sara S Kim

OBJECTIVE: To evaluate the efficacy of fluoxetine in the treatment of anorexia nervosa. DATA SOURCES: Literature obtained through searching MEDLINE (1966–January 2003). DATA SYNTHESIS: Studies conducted on the efficacy of fluoxetine in treating anorexia nervosa have conflicting results. Study design and methodology should be carefully evaluated. CONCLUSIONS: Fluoxetine played a role in the reduction of symptoms of obsessive–compulsive disorder and depression in anorexic patients. While psychotherapy, nutritional therapy, and behavioral therapy should be the mainstays of treatment, fluoxetine should be considered as an option to prevent relapse or to treat associated symptoms of anorexia nervosa following adequate weight restoration as a part of maintenance therapy and not as a primary or acute therapy. Although fluoxetine appears to be promising for the treatment of patients with anorexia nervosa, further studies need to be performed with a larger sample size and/or better design.

CNS Spectrums ◽  
1999 ◽  
Vol 4 (S3) ◽  
pp. 35-40 ◽  
Author(s):  
Fritz Hohagen

AbstractObsessive-compulsive disorder (OCD) has long been considered a treatment-refractory mental condition. Neither pharmacologic nor psychodynamic therapy has been proven to treat OCD effectively. Yet the prognosis for OCD has changed dramatically in recent years with the introduction of behavior therapy and the use of selective serotonin reuptake inhibitors (SSRIs). Many studies have shown that behavior therapy, especially exposure with response prevention, and SSRIs reduce obsessive-compulsive symptoms significantly. Still, many unanswered questions—including the role of cognitive therapy in the treatment of OCD, exposure therapy vs multimodal behavioral therapy, individual versus group therapy, outcome predictors in adults, adolescents, and children, and the role of combination treatment using an SSRI and cognitive-behavioral therapy—remain. This article will explore these issues as well as suggest directions for further research into OCD.


2021 ◽  
pp. 33-34
Author(s):  
Neha Farheen Mushtaq ◽  
G Venkatesh Kumar

BACKGROUND: Obsessive Compulsive Disorder (OCD) is a mental disorder characterized by the presence of obsessions and compulsions with lifetime prevalence of around 2%-3%. Increase in symptoms severity often signicantly seen impairment with work, relationships and other responsibilities. Therefore, timely and effective intervention is required. Literature favors cognitive Behavioral therapy (CBT) as intervention in the management of symptoms severity. AIM: The present study attempts to see the role of mindfulness based cognitive therapy in reducing symptoms severity in OCD. METHODS AND MATERIALS: Pre- and post- MBCT intervention with a control group design were used to conduct this study involving 34 patients with OCD. Patients were equally distributed in two groups where one group was given intervention Mindfulness based cognitive therapy (MBCT) sessions for 8 weeks. Pre- and post- intervention assessment was done using Yale-Brown Obsessive Compulsive Scale (YBOCS) symptoms severity. And the results were compared. RESULTS: Obtained research data indicates that there is a signicant declined in the composite score on YBOCS symptoms severity at post intervention assessment in the group which had been undergone MBCTas compare to the other group. CONCLUSION: Findings revealed that MBCThas a signicant effect on reducing symptoms severity in patients with OCD.


2016 ◽  
Vol 10 (2) ◽  
pp. 91-103 ◽  
Author(s):  
Zoe Marsden

This article reports on the first 3 randomly allocated cases treated by the author in an ongoing trial comparing eye movement desensitization and reprocessing (EMDR) with cognitive behavioral therapy (exposure and response prevention) in the treatment of obsessive-compulsive disorder in a U.K. primary care setting. This article describes the treatment and data collection procedures, followed by a summary of each of the 3 cases supported by quantitative and qualitative data. The Adapted EMDR Phobia Protocol (Marr, 2012) was provided, following the trial protocol of 1-hour, 16-session treatment. The Yale-Brown Obsessive Compulsive Scale was administered at every 4th session. At posttreatment, 2 of the 3 cases showed more than a 50% reduction on validated psychometric measures, with symptoms below diagnostic cutoff. The final case started treatment below the diagnostic cutoff on the primary outcome measure and showed a slight improvement. Six-month follow-up data showed maintenance of treatment effects. Transcripts from a semistructured telephone interview carried out by an independent researcher following treatment were analyzed using a 6-stage thematic analysis method, which identified 3 themes: the role of traumatic experiences, role of shame, and importance of therapeutic alliance. This article concludes with a discussion of implications for EMDR practice and theory.


CNS Spectrums ◽  
2007 ◽  
Vol 12 (S3) ◽  
pp. 59-63 ◽  
Author(s):  
Joseph Zohar ◽  
Eric Hollander ◽  
Dan J. Stein ◽  
Herman G. M. Westenberg ◽  
Herman G. M. Westenberg ◽  
...  

Over the last 25 years, the perception of obsessive-compulsive disorder (OCD) has changed; where once it was seen as a rare refractory disorder, it is now viewed as a fairly prevalent, but treatable, medical condition responding to two main therapeutic strategies—serotonin reuptake inhibitors (SRIs) and cognitive-behavioral therapy (CBT). Given the emergence of new results with SRIs, more data on the role of augmentation strategies with second-generation antipsychotics, and recent genetic and neuroimaging findings with potential for advancing the understanding of the pathogenesis of OCD, it was thought appropriate to revisit OCD in order to identify key developments in this field and examine how they might be translated into the clinical arena.This consensus statement is the product of the International Anxiety Disorders Conference that took place in Cape Town in February 2006, and is referred to as the Cape Town Consensus (CTC).


2020 ◽  
Author(s):  
Charles Scelles ◽  
LUIS CARLO BULNES

Eye Movement Desensitization and Reprocessing (EMDR) is a treatment for post-traumatic stressdisorder (PTSD). The technique is known to stimulate the capacity to reprocess maladaptive memoriesthat are thought to be central to this pathology. Here we investigate if EMDR therapy can be used in otherconditions than PTSD. We conducted a systematic literature search on PubMed, ScienceDirect, Scopus, and Web of Science. Wesearched for published empirical findings on EMDR, excluding those centred on trauma and PTSD,published up to 2020. The results were classified by psychiatric categories.   Ninety articles met our research criteria. A positive effect was reported in addictions, somatoformdisorders, sexual dysfunction, eating disorder, disorders of adult personality, mood disorders, reaction tosevere stress, anxiety disorders, performance anxiety, Obsessive-Compulsive Disorder (OCD), pain,neurodegenerative disorders, paedopsychiatry and sleep. The evidence was more consistent in pain, OCD,mood disorders, and reaction to severe stress.EMDR’s efficiency across numerous pathological situations, highlighted the central role of affectivememory in several psychiatric and non-psychiatric conditions. Furthermore, EMDR seems to besuccessful in usually uncooperative (e.g. Dementia) or unproductive cases (e.g. aphasia). Moreover, insome severe medical situations were psychologic distress was an obstacle, EMDR allowed thecontinuation of treatment-as-usual. Our review suggests that it is a safe and economical therapeuticoption, and its effect in non-pathological situations opens new avenues for translational research. Overallmore methodologically rigorous studies are needed.


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