Advances in FT-IR spectroscopic imaging microscopy of biological tissue using infrared focal-plane array detectors

2000 ◽  
Author(s):  
Linda H. Kidder ◽  
Abigail S. Haka ◽  
Ira W. Levin ◽  
E. Neil Lewis
Keyword(s):  
Biological Tissue ◽  
Focal Plane ◽  
Spectroscopic Imaging ◽  
Focal Plane Array ◽  
Infrared Focal Plane Array ◽  
Array Detectors ◽  
Ft Ir ◽  
Ir Spectroscopic

FT-IR spectroscopic imaging microscopy of wheat kernels using a Mercury–Cadmium–Telluride focal-plane array detector

1999 ◽  
Vol 19 (1) ◽  
pp. 123-129 ◽  
Author(s):  
Curtis Marcott ◽  
Robert C Reeder ◽  
Joseph A Sweat ◽  
Dia D Panzer ◽  
David L Wetzel
Keyword(s):  
Cadmium Telluride ◽  
Focal Plane ◽  
Mercury Cadmium Telluride ◽  
Spectroscopic Imaging ◽  
Focal Plane Array ◽  
Array Detector ◽  
Ft Ir ◽  
Ir Spectroscopic ◽  
Wheat Kernels

Vibrational Spectroscopic Microscopy: Raman, Near-Infrared and Mid-Infrared Imaging Techniques

1995 ◽  
Vol 1 (1) ◽  
pp. 35-46
Author(s):  
E. Neil Lewis ◽  
Ira W. Levin
Keyword(s):  
Focal Plane ◽  
Near Infrared ◽  
Imaging Techniques ◽  
Spectroscopic Imaging ◽  
Focal Plane Array ◽  
Acid Mixture ◽  
Infrared Focal Plane Array ◽  
Mid Infrared ◽  
Array Detectors ◽  
Infrared Spectral

New instrumental approaches for performing vibrational Raman, near-infrared and mid-infrared spectroscopic imaging microscopy are described. The instruments integrate imaging quality filters such as acousto-optic tunable filters (AOTFs), with visible charge-coupled device (CCD) and infrared focal-plane array detectors. These systems are used in conjunction with infinity-corrected, refractive microscopes for operation in the visible and near-infrared spectral regions and with Cassegrainian reflective optics for operation in the mid-infrared spectral interval. Chemically specific images at moderate spectral resolution (2 nm) and high spatial resolution (1 μm) can be collected rapidly and noninvasively. Image data are presented containing 128 × 128 pixels, although significantly larger format images can be collected in approximately the same time. The instruments can be readily configured for both absorption and reflectance spectroscopies. We present Raman emission images of polystyrene microspheres and a lipid/amino acid mixture and near-infrared images of onion epidermis and a hydrated phospholipid dispersion. Images generated from mid-infrared spectral data are presented for a KBr disk containing nonhomogeneous domains of lipid and for 50-μm slices of monkey cerebellum. These are the first results illustrating the use of infrared focal-plane array detectors as chemically specific spectroscopic imaging devices and demonstrating their application in biomolecular areas. Extensions and future applications of the various vibrational spectroscopic imaging techniques are discussed.

Calibration Procedure for Attenuation Coefficient Measurements in Highly Opaque Media Using Infrared Focal Plane Array (IRFPA) Spectroscopy

2018 ◽  
Vol 72 (2) ◽  
pp. 177-187 ◽  
Author(s):  
Sara Kirchner ◽  
Sebastien Narinsamy ◽  
Alain Sommier ◽  
Marta Romano ◽  
Meguya Ryu ◽  
...  
Keyword(s):  
Coming Out ◽  
Focal Plane ◽  
Aqueous Media ◽  
Focal Plane Array ◽  
Calibration Procedure ◽  
Integration Time ◽  
Intensity Level ◽  
Infrared Focal Plane Array ◽  
Ir Spectroscopic

The purpose of this article is to present a new calibration procedure for spectroscopic measurements using an infrared focal plane array (IRFPA) spectrometer on highly opaque middle-wave infrared (MWIR) media. The procedure is based on the properties of the IRFPA camera and especially the integration time (IT), which is the main parameter that can be adjusted to control the sensitivity of the measurements. The goal of the paper is to experimentally validate this dependence with the direct reference intensity light coming out of the IR monochromator in order to predict the spectrum shape and intensity level in a range out of the camera saturation. This method allows determining spectrum used as background for transmittance calculation. It has been applied in the case of measurement of water transmittance, which is a highly opaque medium and whose measurement requires high ITs. The main result is the ability to take an IR spectroscopic imaging measurement through 300 µm of water and the determination of its transmittance with sufficient sensitivity due to the proposed calibration procedure. This procedure allows the possibility of transitory studies in heterogeneous aqueous media.

Evaluation of infrared focal-plane-array detectors

2001 ◽  
Vol 33 (2) ◽  
pp. 183-188
Author(s):  
Werner Gross ◽  
Thomas Hierl ◽  
Max Schulz
Keyword(s):  
Focal Plane ◽  
Focal Plane Array ◽  
Infrared Focal Plane Array ◽  
Array Detectors

Quantitative Determination of Pharmaceutical Drug Formulations by Near-Infrared Spectroscopic Imaging

2008 ◽  
Vol 62 (11) ◽  
pp. 1200-1208 ◽  
Author(s):  
O. Kolomiets ◽  
U. Hoffmann ◽  
P. Geladi ◽  
H. W. Siesler
Keyword(s):  
Quantitative Determination ◽  
Focal Plane ◽  
Near Infrared ◽  
Diffuse Reflection ◽  
Spectroscopic Imaging ◽  
Focal Plane Array ◽  
Drug Formulation ◽  
Array Detector ◽  
Ft Ir

Over the last decade Fourier transform infrared (FT-IR) and near-infrared (NIR) spectroscopic imaging with focal plane array (FPA) detectors have proved powerful techniques for the rapid visualization of samples by a combination of spectroscopic and spatial information. Using these methods, selected sample areas can be analyzed with reference to the identification and localization of chemical species by FT-IR spectroscopy in the transmission or attenuated total reflection (ATR) mode and by NIR spectroscopy in diffuse reflection with a lateral resolution in the micrometer range. The present communication focuses on the quantitative determination of the active ingredient composition of a solid drug formulation by NIR spectroscopic imaging with a focal plane array detector and the results obtained are compared to the quantitative data obtained by conservative light-fiber NIR spectroscopic diffuse reflection measurements with a single-element detector. The communication also addresses the issue of penetration depth of NIR radiation into the investigated solid material.

Growth of InAs/GaSb short-period superlattices for high-resolution mid-wavelength infrared focal plane array detectors

2005 ◽  
Vol 278 (1-4) ◽  
pp. 156-161 ◽  
Author(s):  
M. Walther ◽  
J. Schmitz ◽  
R. Rehm ◽  
S. Kopta ◽  
F. Fuchs ◽  
...  
Keyword(s):  
High Resolution ◽  
Focal Plane ◽  
Focal Plane Array ◽  
Infrared Focal Plane Array ◽  
Array Detectors ◽  
Short Period ◽  
Short Period Superlattices

Photon trapping photodiode design in HgCdTe mid-wavelength infrared focal plane array detectors

2014 ◽  
Vol 46 (10) ◽  
pp. 1385-1390 ◽  
Author(s):  
Z. H. Ye ◽  
P. Zhang ◽  
Y. Li ◽  
Y. Y. Chen ◽  
S. M. Zhou ◽  
...  
Keyword(s):  
Focal Plane ◽  
Focal Plane Array ◽  
Infrared Focal Plane Array ◽  
Array Detectors ◽  
Photon Trapping
Sign in / Sign up

Export Citation Format

Share Document