scholarly journals Hierarchical Distribution Matching: a Versatile Tool for Probabilistic Shaping

Author(s):  
Stella Civelli ◽  
Marco Secondini
Alloy Digest ◽  
1996 ◽  
Vol 45 (7) ◽  

Abstract Crucible S7 is a chromium/molybdenum tool steel developed to produce the unusual combination of high shock resistance and toughness together with ease of machining and heat treatment. It is a versatile tool steel applicable for both hot and cold work shock applications. This datasheet provides information on composition, physical properties, hardness, and elasticity as well as fracture toughness. It also includes information on heat treating, machining, and joining. Filing Code: TS-543. Producer or source: Crucible Service Centers.


2019 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Salah Eddin Khabbaz ◽  
D. Ladhalakshmi ◽  
Merin Babu ◽  
A. Kandan ◽  
V. Ramamoorthy ◽  
...  

Chemosphere ◽  
2021 ◽  
pp. 130778
Author(s):  
Antón Puga ◽  
Marta Pazos ◽  
Emilio Rosales ◽  
Ma Angeles Sanromán

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Kento Ojima ◽  
Kazuki Shiraiwa ◽  
Kyohei Soga ◽  
Tomohiro Doura ◽  
Mikiko Takato ◽  
...  

AbstractThe regulation of glutamate receptor localization is critical for development and synaptic plasticity in the central nervous system. Conventional biochemical and molecular biological approaches have been widely used to analyze glutamate receptor trafficking, especially for α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate-type glutamate receptors (AMPARs). However, conflicting findings have been reported because of a lack of useful tools for analyzing endogenous AMPARs. Here, we develop a method for the rapid and selective labeling of AMPARs with chemical probes, by combining affinity-based protein labeling and bioorthogonal click chemistry under physiological temperature in culture medium. This method allows us to quantify AMPAR distribution and trafficking, which reveals some unique features of AMPARs, such as a long lifetime and a rapid recycling in neurons. This method is also successfully expanded to selectively label N-methyl-D-aspartate-type glutamate receptors. Thus, bioorthogonal two-step labeling may be a versatile tool for investigating the physiological and pathophysiological roles of glutamate receptors in neurons.


Author(s):  
Frank Ecker ◽  
Jennifer Francis ◽  
Per Olsson ◽  
Katherine Schipper

AbstractThis paper investigates how data requirements often encountered in archival accounting research can produce a data-restricted sample that is a non-random selection of observations from the reference sample to which the researcher wishes to generalize results. We illustrate the effects of non-random sampling on results of association tests in a setting with data on one variable of interest for all observations and frequently-missing data on another variable of interest. We develop and validate a resampling approach that uses only observations from the data-restricted sample to construct distribution-matched samples that approximate randomly-drawn samples from the reference sample. Our simulation tests provide evidence that distribution-matched samples yield generalizable results. We demonstrate the effects of non-random sampling in tests of the association between realized returns and five implied cost of equity metrics. In this setting, the reference sample has full information on realized returns, while on average only 16% of reference sample observations have data on cost of equity metrics. Consistent with prior research (e.g., Easton and Monahan The Accounting Review 80, 501–538, 2005), analysis using the unadjusted (non-random) cost of equity sample reveals weak or negative associations between realized returns and cost of equity metrics. In contrast, using distribution-matched samples, we find reliable evidence of the theoretically-predicted positive association. We also conceptually and empirically compare distribution-matching with multiple imputation and selection models, two other approaches to dealing with non-random samples.


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