scholarly journals The presence of knockdown resistance mutations reduces male mating competitiveness in the major arbovirus vector, Aedes aegypti

2021 ◽  
Vol 15 (2) ◽  
pp. e0009121
Author(s):  
Lisa M. Rigby ◽  
Brian J. Johnson ◽  
Gordana Rašić ◽  
Christopher L. Peatey ◽  
Leon E. Hugo ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Insecticide Resistance ◽  
Mating Success ◽  
Host Location ◽  
Beat Frequency ◽  
Male Mating ◽  
Male Mating Success ◽  
Knockdown Resistance ◽  
Resistance Mutations ◽  
Mating Competition

Background The development of insecticide resistance in mosquitoes can have pleiotropic effects on key behaviours such as mating competition and host-location. Documenting these effects is crucial for understanding the dynamics and costs of insecticide resistance and may give researchers an evidence base for promoting vector control programs that aim to restore or conserve insecticide susceptibility. Methods and findings We evaluated changes in behaviour in a backcrossed strain of Aedes aegypti, homozygous for two knockdown resistance (kdr) mutations (V1016G and S989P) isolated in an otherwise fully susceptible genetic background. We compared biting activity, host location behaviours, wing beat frequency (WBF) and mating competition between the backcrossed strain, and the fully susceptible and resistant parental strains from which it was derived. The presence of the homozygous kdr mutations did not have significant effects on blood avidity, the time to locate a host, or WBF in females. There was, however, a significant reduction in mean WBF in males and a significant reduction in estimated male mating success (17.3%), associated with the isolated kdr genotype. Conclusions Our results demonstrate a cost of insecticide resistance associated with an isolated kdr genotype and manifest as a reduction in male mating success. While there was no recorded difference in WBF between the females of our strains, the significant reduction in male WBF recorded in our backcrossed strain might contribute to mate-recognition and mating disruption. These consequences of resistance evolution, especially when combined with other pleiotropic fitness costs that have been previously described, may encourage reversion to susceptibility in the absence of insecticide selection pressures. This offers justification for the implementation of insecticide resistance management strategies based on the rotation or alternation of different insecticide classes in space and time.

scholarly journals Male competition and the evolution of mating and life-history traits in experimental populations of Aedes aegypti

2019 ◽  
Vol 286 (1904) ◽  
pp. 20190591 ◽  
Author(s):  
Alima Qureshi ◽  
Andrew Aldersley ◽  
Brian Hollis ◽  
Alongkot Ponlawat ◽  
Lauren J. Cator
Keyword(s):  
Life History ◽  
Aedes Aegypti ◽  
Mating Success ◽  
Life History Traits ◽  
Male Competition ◽  
Male Mating ◽  
Male Mating Success ◽  
Reproductive Control ◽  
Evolutionary Response ◽  
Mating Conditions

Aedes aegypti is an important disease vector and a major target of reproductive control efforts. We manipulated the opportunity for sexual selection in populations of Ae . aegypti by controlling the number of males competing for a single female. Populations exposed to higher levels of male competition rapidly evolved higher male competitive mating success relative to populations evolved in the absence of competition, with an evolutionary response visible after only five generations. We also detected correlated evolution in other important mating and life-history traits, such as acoustic signalling, fecundity and body size. Our results indicate that there is ample segregating variation for determinants of male mating competitiveness in wild populations and that increased male mating success trades-off with other important life-history traits. The mating conditions imposed on laboratory-reared mosquitoes are likely a significant determinant of male mating success in populations destined for release.

scholarly journals Male competition and the evolution of mating and life history traits in experimental populations of Aedes aegypti

2019 ◽  
Author(s):  
Alima Qureshi ◽  
Andrew Aldersley ◽  
Brian Hollis ◽  
Alongkot Ponlawat ◽  
Lauren J. Cator
Keyword(s):  
Life History ◽  
Aedes Aegypti ◽  
Mating Success ◽  
Life History Traits ◽  
Male Competition ◽  
Male Mating ◽  
Male Mating Success ◽  
Reproductive Control ◽  
Evolutionary Response ◽  
Mating Conditions

AbstractAedes aegypti is an important disease vector and a major target of reproductive control efforts. We manipulated the opportunity for sexual selection in populations of Ae. aegypti by controlling the number of males competing for a single female. Populations exposed to higher levels of male competition rapidly evolved higher male competitive mating success relative to populations evolved in the absence of competition, with an evolutionary response visible after only five generations. We also detected correlated evolution in other important mating and life history traits, such as acoustic signalling, fecundity and body size. Our results indicate that there is ample segregating variation for determinants of male mating competitiveness in wild populations and that increased male mating success trades-off with other important life history traits. The mating conditions imposed on laboratory-reared mosquitoes are likely a significant determinant of male mating success in populations destined for release.

scholarly journals Cuticular hydrocarbons are associated with mating success and insecticide resistance in malaria vectors

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Kelsey L. Adams ◽  
Simon P. Sawadogo ◽  
Charles Nignan ◽  
Abdoulaye Niang ◽  
Douglas G. Paton ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Cuticular Hydrocarbons ◽  
Mating Success ◽  
Resistance Management ◽  
Malaria Vectors ◽  
Male Mating ◽  
Anopheles Coluzzii ◽  
Male Mating Success ◽  
Female Ratio ◽  
Male To Female

AbstractAnopheles coluzzii females, important malaria vectors in Africa, mate only once in their lifetime. Mating occurs in aerial swarms with a high male-to-female ratio, where traits underlying male mating success are largely unknown. Here, we investigated whether cuticular hydrocarbons (CHCs) influence mating success in natural mating swarms in Burkina Faso. As insecticides are widely used in this area for malaria control, we also determined whether CHCs affect insecticide resistance levels. We find that mated males have higher CHC abundance than unmated controls, suggesting CHCs could be determinants of mating success. Additionally, mated males have higher insecticide resistance under pyrethroid challenge, and we show a link between resistance intensity and CHC abundance. Taken together, our results suggest that CHC abundance may be subject to sexual selection in addition to selection by insecticide pressure. This has implications for insecticide resistance management, as these traits may be sustained in the population due to their benefits in mating even in the absence of insecticides.

Longevity and Male Mating Success in Drosophila pseudoobscura

1981 ◽  
Vol 117 (6) ◽  
pp. 1035-1039 ◽  
Author(s):  
Charles E. Taylor ◽  
Cindra Condra ◽  
Michael Conconi ◽  
Mary Prout
Keyword(s):  
Mating Success ◽  
Drosophila Pseudoobscura ◽  
Male Mating ◽  
Male Mating Success

scholarly journals ADAPTATION AT SPECIFIC LOCI. IV. DIFFERENTIAL MATING SUCCESS AMONG GLYCOLYTIC ALLOZYME GENOTYPES OF COLIAS BUTTERFLIES

Genetics ◽  
1985 ◽  
Vol 109 (1) ◽  
pp. 157-175
Author(s):  
Ward B Watt ◽  
Patrick A Carter ◽  
Sally M Blower
Keyword(s):  
Mating Success ◽  
Initial Study ◽  
Heterozygote Advantage ◽  
Male Mating ◽  
Genotype Distribution ◽  
Male Mating Success ◽  
Evolutionary Forces ◽  
Fitness Index ◽  
In The Wild ◽  
Specific Variation

ABSTRACT Male mating success as a function of genotype is an important fitness component. It can be studied in wild populations, in species for which a given group of progeny has exactly one father, by determining genotypes of wild-caught mothers and of sufficient numbers of their progeny. Here, we study male mating success as a function of allozyme genotype at two glycolytic loci in Colias butterflies, in which sperm precedence is complete, so that the most recent male to mate fathers all of a female's subsequent progeny.—For the phosphoglucose isomerase, PGI, polymorphism, we predict mating advantage and disadvantage of male genotypes based on evaluation of their biochemical functional differences in the context of thermal-physiological-ecological constraints on the insects' flight activity. As predicted, we find major, significant advantage in mating success for kinetically favored genotypes, compared to the genotype distribution of males active with the sampled females in the wild. These effects are repeatable among samples and on different semispecies' genetic backgrounds.—Initial study of the phosphoglucomutase, PGM, polymorphism in the same samples reveals heterozygote advantage in male-mating success, compared to males active with the females sampled. This contrasts with a lack of correspondence between PGI and PGM genotypes in other fitness index or component differences.—Epistatic interactions in mating success between the two loci are absent.—There is no evidence for segregation distortion associated with the alleles of either primary locus studied, nor is there significant assortative mating.—These results extend our understanding of the specific variation studied and suggest that even loci closely related in function may have distinctive experience of evolutionary forces. Implications of the specificity of the effects seen are briefly discussed.

Sign in / Sign up

Export Citation Format

Share Document