Sweet Taste Receptor Expressed in Pancreatic β-Cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion

PLoS ONE ◽

10.1371/journal.pone.0005106 ◽

2009 ◽

Vol 4 (4) ◽

pp. e5106 ◽

Author(s):

Yuko Nakagawa ◽

Masahiro Nagasawa ◽

Satoko Yamada ◽

Akemi Hara ◽

Hideo Mogami ◽

...

Keyword(s):

Insulin Secretion ◽

Taste Receptor ◽

Sweet Taste ◽

Β Cells ◽

Pancreatic Β Cells ◽

Signaling Systems ◽

Sweet Taste Receptor ◽

Cyclic Amp Signaling

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Acute exposure to 3‑deoxyglucosone at high glucose levels impairs insulin secretion from β‑cells by downregulating the sweet taste receptor signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2019.10163 ◽

2019 ◽

Author(s):

Xiudao Song ◽

Guoqiang Liang ◽

Min Shi ◽

Liang Zhou ◽

Fei Wang ◽

...

Keyword(s):

Insulin Secretion ◽

Signaling Pathway ◽

High Glucose ◽

Taste Receptor ◽

Sweet Taste ◽

Acute Exposure ◽

Β Cells ◽

Glucose Levels ◽

Sweet Taste Receptor ◽

Receptor Signaling Pathway

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The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells

Diabetes & Metabolism Journal ◽

10.4093/dmj.2011.35.5.451 ◽

2011 ◽

Vol 35 (5) ◽

pp. 451 ◽

Author(s):

Itaru Kojima ◽

Yuko Nakagawa

Keyword(s):

Taste Receptor ◽

Sweet Taste ◽

Enteroendocrine Cells ◽

Β Cells ◽

Pancreatic Β Cells ◽

Sweet Taste Receptor

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Correction to: Sweet taste receptors as a tool for an amplifying pathway of glucose-stimulated insulin secretion in pancreatic β cells

Pflügers Archiv - European Journal of Physiology ◽

10.1007/s00424-019-02284-1 ◽

2019 ◽

Vol 471 (7) ◽

pp. 1041-1041 ◽

Author(s):

Jae-Hyung Park ◽

Dae-Kyu Song

Keyword(s):

Insulin Secretion ◽

Sweet Taste ◽

Taste Receptors ◽

Β Cells ◽

Pancreatic Β Cells ◽

Sweet Taste Receptors ◽

Glucose Stimulated Insulin Secretion ◽

Amplifying Pathway

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Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic β-cells

Cellular Signalling ◽

10.1016/j.cellsig.2010.04.001 ◽

2010 ◽

Vol 22 (8) ◽

pp. 1240-1246 ◽

Author(s):

Weijuan Shao ◽

Zhiwen Yu ◽

I George Fantus ◽

Tianru Jin

Keyword(s):

Β Cells ◽

Pancreatic Β Cells ◽

Interacting Protein ◽

Proteasome Degradation ◽

Thioredoxin Interacting Protein ◽

Cyclic Amp Signaling

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Sweet taste receptors as a tool for an amplifying pathway of glucose-stimulated insulin secretion in pancreatic β cells

Pflügers Archiv - European Journal of Physiology ◽

10.1007/s00424-019-02271-6 ◽

2019 ◽

Vol 471 (4) ◽

pp. 655-657 ◽

Author(s):

Jae-Hyung Park ◽

Dae-Kyu Song

Keyword(s):

Insulin Secretion ◽

Sweet Taste ◽

Taste Receptors ◽

Β Cells ◽

Pancreatic Β Cells ◽

Sweet Taste Receptors ◽

Glucose Stimulated Insulin Secretion ◽

Amplifying Pathway

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Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1115183109 ◽

2012 ◽

Vol 109 (8) ◽

pp. E524-E532 ◽

Author(s):

G. A. Kyriazis ◽

M. M. Soundarapandian ◽

B. Tyrberg

Keyword(s):

Insulin Secretion ◽

Taste Receptor ◽

Sweet Taste ◽

Receptor Signaling ◽

Sweet Taste Receptor ◽

Glucose Stimulated Insulin Secretion

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Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells

Molecular and Cellular Endocrinology ◽

10.1016/j.mce.2014.07.004 ◽

2014 ◽

Vol 394 (1-2) ◽

pp. 70-79 ◽

Author(s):

Yoshiaki Ohtsu ◽

Yuko Nakagawa ◽

Masahiro Nagasawa ◽

Shigeki Takeda ◽

Hirokazu Arakawa ◽

...

Keyword(s):

Taste Receptor ◽

Sweet Taste ◽

Signaling Systems ◽

Sweet Taste Receptor

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Faculty Opinions recommendation of Functional roles of the sweet taste receptor in oral and extraoral tissues.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718461846.793523436 ◽

2016 ◽

Author(s):

Jonathan Kaunitz

Keyword(s):

Taste Receptor ◽

Sweet Taste ◽

Functional Roles ◽

Sweet Taste Receptor

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TAS1R2 Sweet Taste Receptor Genetic Variation and Dietary Intake in Korean Females

Appetite ◽

10.1016/j.appet.2021.105281 ◽

2021 ◽

pp. 105281

Author(s):

Jeong-Hwa Choi

Keyword(s):

Genetic Variation ◽

Dietary Intake ◽

Taste Receptor ◽

Sweet Taste ◽

Sweet Taste Receptor

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Sucralose and Acesulfame K modulate human and rodent vascular smooth muscle contractility independently of the presence of the sweet taste receptor. A study of the SOSweet project

Archives of Cardiovascular Diseases Supplements ◽

10.1016/j.acvdsp.2021.04.098 ◽

2021 ◽

Vol 13 (2) ◽

pp. 186

Author(s):

S. Battault ◽

S. Risdon ◽

R. Bouvet ◽

D. Sigaudo-Roussel ◽

P. De Santa Barbara ◽

...

Keyword(s):

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Taste Receptor ◽

Sweet Taste ◽

Muscle Contractility ◽

Smooth Muscle Contractility ◽

Sweet Taste Receptor

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