RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib

PLoS ONE ◽

10.1371/journal.pone.0066003 ◽

2013 ◽

Vol 8 (6) ◽

pp. e66003 ◽

Author(s):

James R. Bradford ◽

Matthew Farren ◽

Steve J. Powell ◽

Sarah Runswick ◽

Susie L. Weston ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Mrna Expression ◽

Kinase Inhibitor ◽

Rna Seq ◽

Human Tumour ◽

Human Tumour Xenografts ◽

Tumour Xenografts ◽

Vegfr Tyrosine Kinase Inhibitor

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Use of intratumoral mRNA expression of genes involved in angiogenesis and HIF1 pathway to predict outcome to VEGFR tyrosine kinase inhibitor (TKI) in patients enrolled in CONFIRM1 and CONFIRM2

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.4002 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 4002-4002 ◽

Author(s):

P. M. Wilson ◽

D. Yang ◽

M. M. Shi ◽

W. Zhang ◽

C. Jacques ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Mrna Expression ◽

Kinase Inhibitor ◽

Expression Of Genes ◽

Vegfr Tyrosine Kinase Inhibitor

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VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2014.09.005 ◽

2014 ◽

Vol 280 (3) ◽

pp. 408-420 ◽

Author(s):

Shang Li ◽

Yuan Ye Dang ◽

Ginny Oi Lam Che ◽

Yiu Wa Kwan ◽

Shun Wan Chan ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Vascular Toxicity ◽

Vascular Insufficiency ◽

Vascular Preservation ◽

Vegfr Tyrosine Kinase Inhibitor

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BIONIKK: A phase 2 biomarker driven trial with nivolumab and ipilimumab or VEGFR tyrosine kinase inhibitor (TKI) in naïve metastatic kidney cancer

Bulletin du Cancer ◽

10.1016/s0007-4551(20)30283-6 ◽

2020 ◽

Vol 107 (5) ◽

pp. eS22-eS27 ◽

Author(s):

Nicolas Epaillard ◽

Audrey Simonaggio ◽

Reza Elaidi ◽

Fouzia Azzouz ◽

Elena Braychenko ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kidney Cancer ◽

Kinase Inhibitor ◽

Phase 2 ◽

Vegfr Tyrosine Kinase Inhibitor

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Acute left ventricular dysfunction induced by a panHER and VEGFR tyrosine kinase inhibitor in a phase I trial

Investigational New Drugs ◽

10.1007/s10637-009-9252-6 ◽

2009 ◽

Vol 28 (3) ◽

pp. 350-352 ◽

Author(s):

Rastislav Bahleda ◽

Christophe Massard ◽

Jean-Charles Soria ◽

Hassan Izzedine ◽

Ariel Cohen ◽

...

Keyword(s):

Tyrosine Kinase ◽

Phase I ◽

Tyrosine Kinase Inhibitor ◽

Left Ventricular Dysfunction ◽

Phase I Trial ◽

Ventricular Dysfunction ◽

Kinase Inhibitor ◽

Left Ventricular ◽

Vegfr Tyrosine Kinase Inhibitor

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Pharmacokinetics (PK) and tolerability of GW786034, a VEGFR tyrosine kinase inhibitor, after daily oral administration to patients with solid tumors

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3054 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3054-3054 ◽

Author(s):

A. B. Suttle ◽

H. Hurwitz ◽

A. Dowlati ◽

N. Fernando ◽

S. Savage ◽

...

Keyword(s):

Oral Administration ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Solid Tumors ◽

Kinase Inhibitor ◽

Daily Oral Administration ◽

Vegfr Tyrosine Kinase Inhibitor

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Non-VEGFR Tyrosine Kinase Inhibitor

10.32388/gnr65l ◽

2020 ◽

Author(s):

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Vegfr Tyrosine Kinase Inhibitor

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Inflammatory Corneal (Lymph)angiogenesis Is Blocked by VEGFR-Tyrosine Kinase Inhibitor ZK 261991, Resulting in Improved Graft Survival after Corneal Transplantation

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.07-1314 ◽

2008 ◽

Vol 49 (5) ◽

pp. 1836 ◽

Author(s):

Deniz Hos ◽

Felix Bock ◽

Tina Dietrich ◽

Jasmine Onderka ◽

Friedrich E. Kruse ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Graft Survival ◽

Kinase Inhibitor ◽

Corneal Transplantation ◽

Vegfr Tyrosine Kinase Inhibitor

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Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor

Cancer Research ◽

10.1158/0008-5472.can-03-2619 ◽

2005 ◽

Vol 65 (20) ◽

pp. 9253-9260 ◽

Author(s):

Young Ro Kim ◽

Anna Yudina ◽

JoseLuis Figueiredo ◽

Wilfried Reichardt ◽

Dana Hu-Lowe ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Blood Volume ◽

Kinase Inhibitor ◽

Colon Adenocarcinoma ◽

Human Colon ◽

Human Colon Adenocarcinoma ◽

Vegfr Tyrosine Kinase Inhibitor

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A phase I dose escalation trial of the VEGFR tyrosine kinase inhibitor, PTK787/ ZK222584 (PTK/ZK), used in combination with paclitaxel in patients with advanced solid tumors with pharmacokinetic (PK) analysis

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.14521 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 14521-14521

Author(s):

S. R. Malireddy ◽

E. G. Chiorean ◽

A. Younger ◽

D. Jones ◽

M. Waddell ◽

...

Keyword(s):

Tyrosine Kinase ◽

Phase I ◽

Tyrosine Kinase Inhibitor ◽

Solid Tumors ◽

Dose Escalation ◽

Kinase Inhibitor ◽

Advanced Solid Tumors ◽

Vegfr Tyrosine Kinase Inhibitor

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596 The Effect of Rifampin On the Pharmacokinetics of Tivozanib, a Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor

European Journal of Cancer ◽

10.1016/s0959-8049(12)72393-6 ◽

2012 ◽

Vol 48 ◽

pp. 183 ◽

Author(s):

M. Cotreau ◽

D. Subic ◽

L. Massmanian ◽

A. Strahs ◽

D. Vargo

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Endothelial Growth Factor ◽

Vegfr Tyrosine Kinase Inhibitor

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