scholarly journals A Particle Model for Prediction of Cement Infiltration of Cancellous Bone in Osteoporotic Bone Augmentation

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e67958 ◽  
Author(s):  
Ehsan Basafa ◽  
Ryan J. Murphy ◽  
Michael D. Kutzer ◽  
Yoshito Otake ◽  
Mehran Armand
2019 ◽  
Vol 9 (8) ◽  
pp. 1525 ◽  
Author(s):  
Shen ◽  
Kim ◽  
Kang ◽  
Yeom

Although dual-threaded pedicle screws have been developed, the advantages over single-threaded screws remain controversial. We aimed to investigate the biomechanical performance of two types of dual-threaded pedicle screw by comparing their pullout strength with that of a single-threaded screw in relation to bone quality. Four types of pedicle screw with different thread patterns were designed. Type I: single-threaded screw; Type II: double-threaded screw; Type III: dual-threaded screw; Type IV: a newly designed double dual-threaded screw. Five types of polyurethane foams simulating various degrees of bone quality were used. These were: Type A: cancellous bone; Type B: cancellous bone with cortical bone in the upper margin; Type C: osteoporotic cancellous bone; Type D: osteoporotic cancellous bone with cortical bone in the upper margin; and Type E: osteoporotic bone with cortical bone in the upper and lower margins. A comparison of the pullout strength of Type I, II, and III screws in Type A, B, C and D bone specimens was performed. Type C and E bone specimens were used for comparisons among Type I, II, and IV screws. Compared to the single-threaded screw, the dual-threaded pedicle screws exhibited higher pullout strength in normal-quality bone and significantly lower pullout strength in compromised osteoporotic bone. However, the double dual-threaded screw exhibited better pullout biomechanics in osteoporotic bone with bi-cortical bone.


Author(s):  
Purvi S. D. Patel ◽  
Duncan E. T. Shepherd ◽  
David W. L. Hukins

Rigid polyurethane (PU) foam is widely used as a test medium for mimicking human cancellous bone e.g. for investigating fixation of bone screws [1,2]. Whilst the solid and higher density PU foams are used as standard test materials [3], very little work has been carried out to date on modelling human osteoporotic bone. Osteoporosis (OP) is a bone disease in which bone resorption exceeds bone deposition, resulting in bone loss. Various low density, open cell rigid PU foams are available for use as OP bone models, but none of these has been standardised or universally accepted as a test material. In this study the objective was to determine whether low density PU foam might be suitable for mimicking human osteoporotic bone.


2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Karina Klein ◽  
Enrico Zamparo ◽  
Peter W Kronen ◽  
Katharina Kämpf ◽  
Mariano Makara ◽  
...  

Author(s):  
Amirhossein Farvardin ◽  
Mehran Armand

Abstract A potential effective treatment for prevention of osteoporotic hip fractures is augmentation of the mechanical properties of the femur by injecting it with Polymethyl-Methacrylate (PMMA). We have previously developed a preoperative planning workstation to optimize the pattern of cement injection. In this planning paradigm, injections occur on a straight line limiting the overall match between the optimal and injected volumes of the cement. In addition, new advancements in drilling techniques has made it possible to plan and drill the bone based on a curved trajectory. In this study, we introduced a methodology to find the optimal drill path for PMMA injection. With the aid of Finite Element (FE) and hydrodynamic simulations, the effectiveness of the proposed approach was evaluated. Results showed that with an average injection of 7.2 ml, the proposed method can increase the yield load of the femur by 69%. Future works involve experimental validation of this method in cadaveric studies.


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