scholarly journals The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-Control Study and Gene Expression Analyses

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e98899 ◽  
Author(s):  
Natalia Castaño-Rodríguez ◽  
Nadeem O. Kaakoush ◽  
Khean-Lee Goh ◽  
Kwong Ming Fock ◽  
Hazel M. Mitchell
2008 ◽  
Vol 19 (8) ◽  
pp. 869-877 ◽  
Author(s):  
Meira Epplein ◽  
Abraham M. Y. Nomura ◽  
Jean H. Hankin ◽  
Martin J. Blaser ◽  
Guillermo Perez-Perez ◽  
...  

2021 ◽  
Author(s):  
Delniya Khani ◽  
Manouchehr Ahmadi Hedayati ◽  
Farshad Sheikhesmaeili ◽  
Roghaie Ghadiany ◽  
Sherko Nasseri

Abstract Background: ZAK protein is a member of the MLK family proteins defined as mediators in the cell cycle. A survey of zak gene expression in gastric antral epithelial cells (GAECs) of gastritis and gastric adenocarcinoma patients with Helicobacter pylori genotypes infection can elucidate carcinogenesis of H. pylori genotypes.Methods: In a case-control study, zak gene expression was evaluated in GAECs biopsy samples of gastritis patients with (n 23) and without H. pylori infection (n 27) and gastric adenocarcinoma patients with (n 21) and without (n 32) H. pylori infection. The zak gene expression was measured using the relative Real-Time RT PCR.Results: zak gene expression was higher in GAECs of gastritis cancer than in gastric adenocarcinoma, indicating the protective effect of ZAK against gastric cancer (p< 0.005). Conclusion: Reducing zak gene expression has the negative corelations with H. pylori infection and gastric adenocarcinoma.


2005 ◽  
Vol 52 (2) ◽  
pp. 138-146 ◽  
Author(s):  
Hyun Ja Kim ◽  
Mi Kyung Kim ◽  
Woong Ki Chang ◽  
Ho Soon Choi ◽  
Bo Youl Choi ◽  
...  

GERMS ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 182-187 ◽  
Author(s):  
Christina Tsigalou ◽  
Theocharis G Konstantinidis ◽  
Dimitrios Cassimos ◽  
Alexandros Karvelas ◽  
Anastasia Grapsa ◽  
...  

2005 ◽  
Vol 165 (13) ◽  
pp. 1552 ◽  
Author(s):  
Ming-Shiang Wu ◽  
Wei-Jei Lee ◽  
Hsih-Hsi Wang ◽  
Shi-Pei Huang ◽  
Jaw-Town Lin

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