scholarly journals Dynamic Responses of Selective Brain White Matter Fiber Tracts to Binge Alcohol and Recovery in the Rat

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0124885 ◽  
Author(s):  
Adolf Pfefferbaum ◽  
Natalie M. Zahr ◽  
Dirk Mayer ◽  
Torsten Rohlfing ◽  
Edith V. Sullivan
Author(s):  
Angela D. Friederici ◽  
Noam Chomsky

An adequate description of the neural basis of language processing must consider the entire network both with respect to its structural white matter connections and the functional connectivities between the different brain regions as the information has to be sent between different language-related regions distributed across the temporal and frontal cortex. This chapter discusses the white matter fiber bundles that connect the language-relevant regions. The chapter is broken into three sections. In the first, we look at the white matter fiber tracts connecting the language-relevant regions in the frontal and temporal cortices; in the second, the ventral and dorsal pathways in the right hemisphere that connect temporal and frontal regions; and finally in the third, the two syntax-relevant and (at least) one semantic-relevant neuroanatomically-defined networks that sentence processing is based on. From this discussion, it becomes clear that online language processing requires information transfer via the long-range white matter fiber pathways that connect the language-relevant brain regions within each hemisphere and between hemispheres.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Xiangdong Wang ◽  
Chunyao Zhou ◽  
Lei Wang ◽  
Yinyan Wang ◽  
Tao Jiang

Abstract Gliomas grow and invade along white matter fiber tracts. This study assessed the effects of motor cortex gliomas on the cerebral white matter fiber bundle skeleton. The motor cortex glioma group included 21 patients, and the control group comprised 14 healthy volunteers. Both groups underwent magnetic resonance imaging-based 3.0 T diffusion tensor imaging. We used tract-based spatial statistics to analyze the characteristics of white matter fiber bundles. The left and right motor cortex glioma groups were analyzed separately from the control group. Results were statistically corrected by the family-wise error rate. Compared with the controls, patients with left motor cortex gliomas exhibited significantly reduced fractional anisotropy and an increased radial diffusivity in the corpus callosum. The alterations in mean diffusivity (MD) and the axial diffusivity (AD) were widely distributed throughout the brain. Furthermore, atlas-based analysis showed elevated MD and AD in the contralateral superior fronto-occipital fasciculus. Motor cortex gliomas significantly affect white matter fiber microstructure proximal to the tumor. The range of affected white matter fibers may extend beyond the tumor-affected area. These changes are primarily related to early stage tumor invasion.


2015 ◽  
Vol 8 ◽  
pp. 110-116 ◽  
Author(s):  
Amgad Droby ◽  
Vinzenz Fleischer ◽  
Marco Carnini ◽  
Hilga Zimmermann ◽  
Volker Siffrin ◽  
...  

NeuroImage ◽  
1999 ◽  
Vol 9 (4) ◽  
pp. 393-406 ◽  
Author(s):  
J. Rademacher ◽  
V. Engelbrecht ◽  
U. Bürgel ◽  
H.-J. Freund ◽  
K. Zilles

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