scholarly journals Anatomic Correlation of the Mini-Mental State Examination: A Voxel-Based Morphometric Study in Older Adults

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0162889 ◽  
Author(s):  
Mickael Dinomais ◽  
Sebastien Celle ◽  
Guillaume T. Duval ◽  
Frederic Roche ◽  
Samir Henni ◽  
...  
Author(s):  
Ngeemasara Thapa ◽  
Boram Kim ◽  
Ja-Gyeong Yang ◽  
Hye-Jin Park ◽  
Minwoo Jang ◽  
...  

Our study examined the association between chronotype, daily physical activity, and the estimated risk of dementia in 170 community-dwelling older adults. Chronotype was assessed with the Horne–Östberg Morningness–Eveningness Questionnaire (MEQ). Daily physical activity (of over 3 METs) was measured with a tri-axial accelerometer. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to measure the estimated risk of dementia. The evening chronotype, low daily physical activity, and dementia were positively associated with each other. The participants with low physical activity alongside evening preference had 3.05 to 3.67 times higher estimated risk of developing dementia, and participants with low physical activity and morning preference had 1.95 to 2.26 times higher estimated risk than those with high physical activity and morning preference. Our study design does not infer causation. Nevertheless, our findings suggest that chronotype and daily physical activity are predictors of the risk of having dementia in older adults aged 70 years and above.


Author(s):  
Carol Hudon ◽  
Olivier Potvin ◽  
Marie-Christine Turcotte ◽  
Catherine D’Anjou ◽  
Micheline Dubé ◽  
...  

ABSTRACTThis study was aimed at providing normative data for the Mini-Mental State Examination (MMSE). The norms were built from a sample (n = 2409) of community-dwelling French speaking residents from Québec aged 65 and older. The analyses indicated that socio-demographic variables such as education level, age, and gender of individuals influenced significantly the scores of older adults on the MMSE. More precisely, MMSE scores increased with education level and decreased with age. Moreover, women had significantly higher scores than men. On this basis, distinct tables of normative data were produced for women and men. In each table, the MMSE scores corresponding to percentiles 5, 10, 15 and 50 were identified according to four age categories and three education levels. Overall, the use of the present normative data by clinicians will improve their accuracy in detecting cognitive impairment in older adults from Québec.


2012 ◽  
Vol 24 (11) ◽  
pp. 1725-1731 ◽  
Author(s):  
Cláudia Rodrigues Monteiro Macuco ◽  
Samila Satler Tavares Batistoni ◽  
Andrea Lopes ◽  
Meire Cachioni ◽  
Deusivânia Vieira da Silva Falcão ◽  
...  

ABSTRACTBackground: Frailty in older adults is a multifactorial syndrome defined by low metabolic reserve, less resistance to stressors, and difficulty in maintaining organic homeostasis due to cumulative decline of multiple physiological systems. The relationship between frailty and cognition remains unclear and studies about Mini-Mental State Examination (MMSE) performance and frailty are scarce. The objective was to examine the association between frailty and cognitive functioning as assessed by the MMSE and its subdomains.Methods: A cross-sectional population-based study (FIBRA) was carried out in Ermelino Matarazzo, a poor subdistrict of the city of São Paulo, Brazil. Participants were 384 community dwelling older adults, 65 years and older who completed the MMSE and a protocol to assess frailty criteria as described in the Cardiovascular Health Study (CHS).Results: Frail older adults had significantly worse performance on the MMSE (p < 0.001 for total score). Linear regression analyses showed that the MMSE total score was influenced by age (p < 0.001), education (p < 0.001), family income (p < 0.001), and frailty status (p < 0.036). Being frail was associated more significantly with worse scores in Time Orientation (p < 0.004) and Immediate Memory (p < 0.001).Conclusions: Our data suggest that being frail is associated with worse cognitive performance, as assessed by the MMSE. It is recommended that the assessment of frail older adults should include the investigation of their cognitive status.


2020 ◽  
Vol 41 (12) ◽  
pp. 1315-1323
Author(s):  
Sulaiman Alshammari ◽  
Adel Alhamdan ◽  
Saad Bindawas ◽  
Maysoon Al-Amoud ◽  
Saada Al-Orf ◽  
...  

Author(s):  
Αντωνία Χατζηευφραιμίδου ◽  
Δέσποινα Μωραΐτου ◽  
Γεωργία Παπαντωνίου ◽  
Έλενα Ναζλίδου ◽  
Κρυσταλλία Πάντσιου

Η παρούσα έρευνα αποσκοπούσε να εξετάσει τη σχέση ηλικίας - κοινωνικής νόησης.<br />Το δείγμα αποτελούνταν από 72 άτομα, ηλικίας 20 ως 82 ετών, κατανεμημένα σε<br />τρεις ομάδες ηλικίας: τους «Νέους Ενήλικες» (Μ.Ο. = 25 έτη, Τ.Α. = 3.7 έτη), τους<br />«Μεσήλικες» (Μ.Ο. = 51.2 έτη, Τ.Α. = 7.5 έτη) και τους «Ηλικιωμένους» (Μ.Ο. =<br />72.1 έτη, Τ.Α. = 4.9 έτη). Οι τρεις ομάδες ήταν εξισωμένες ως προς το φύλο και το<br />μορφωτικό επίπεδο. Στους συμμετέχοντες χορηγήθηκε η Δοκιμασία Κοινωνικού<br />Συμπερασμού (Απλός) [ΔΚΣ(Α). Social Inference (Minimal) – SI(M): Part 2 of the<br />ΤΑSIT, McDonald, Flanagan,Rollins &amp; Kinch, 2003], η οποία εξετάζει εάν ο<br />συμμετέχοντας κατανοεί το σαρκασμό και μπορεί να τον διακρίνει από την<br />ειλικρίνεια. Στην ομάδα των ηλικιωμένων χορηγήθηκαν επιπλέον η Δοκιμασία<br />Σύντομης Γνωστικής Εκτίμησης (ΔΣΓΕ, Mini Mental State Examination, MMSE,<br />Folstein, Folstein, &amp; McHugh, 1975, προσαρμογή στον ελληνικό πληθυσμό:<br />Fountoulakis, Tsolaki, Chatzi &amp; Kazis, 2000) και η Γηριατρική Κλίμακα<br />Κατάθλιψης-15 (ΓΚΚ-15, Geriatric Depression Scale–15, GDS-15, Yesavage, et al.,<br />1982-1983, προσαρμογή στον ελληνικό πληθυσμό: Fountoulakis, Tsolaki, Iacovides,<br />et al., 1999). Τα αποτελέσματα για τους ηλικιωμένους έδειξαν ότι όσο πιο χαμηλή η<br />βαθμολογία στη ΔΣΓΕ και όσο πιο υψηλή στη ΓΚΚ-15, τόσο χαμηλότερη η επίδοση<br />στη ΔΚΣ(Α). Για το σύνολο του δείγματος, τα αποτελέσματα έδειξαν πως η ηλικία<br />2<br />συνδέεται αρνητικά με την ικανότητα κατανόησης του σαρκασμού και η αυτο-<br />αναφερόμενη υπερχοληστεριναιμία αποτελεί επιβαρυντικό παράγοντα στην<br />παραπάνω σχέση.


2018 ◽  
Vol 31 (5) ◽  
pp. 693-701 ◽  
Author(s):  
Ryan Van Patten ◽  
Karysa Britton ◽  
Geoffrey Tremont

ABSTRACTObjectives:To show enhanced psychometric properties and clinical utility of the modified Mini-Mental State Examination (3MS) compared to the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI).Design:Psychometric and clinical comparison of the 3MS and MMSE.Setting:Neuropsychological clinic in the northeastern USA.Participants:Older adults referred for cognitive concerns, 87 of whom were cognitively intact (CI) and 206 of whom were diagnosed with MCI.Measurements:The MMSE, the 3MS, and comprehensive neuropsychological evaluations.Results:Both instruments were significant predictors of diagnostic outcome (CI or MCI), with comparable odds ratios, but the 3MS explained more variance and showed improved classification accuracies relative to the MMSE. The 3MS also demonstrated greater receiver operating characteristic area under the curve values (0.85, SE = 0.02) compared to the MMSE (0.74, SE = 0.03). Scoring lower than 95/100 on the 3MS suggested MCI, while scoring lower than 28/30 on the MMSE suggested MCI. Additionally, compared to the MMSE, the 3MS shared more variance with neuropsychological composite scores in Language and Memory domains but not in Attention, Visuospatial, and Executive domains. Finally, 65.5% MCI patients were classified as impaired (scoring ≤1 SD below the mean) using 3MS normative data, compared to only 11.7% of patients who were classified as impaired using MMSE normative data.Conclusions:Broadly speaking, our data strongly favor the widespread substitution of the MMSE with the 3MS in older adults with concerns for cognitive decline.


Sign in / Sign up

Export Citation Format

Share Document