scholarly journals Longitudinal analysis of antibody responses in symptomatic malaria cases do not mirror parasite transmission in peri-urban area of Cote d’Ivoire between 2010 and 2013

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0172899 ◽  
Author(s):  
David Koffi ◽  
Marie-Louise Varela ◽  
Cheikh Loucoubar ◽  
Sylvain Beourou ◽  
Inès Vigan-Womas ◽  
...  
2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Julie K. Sackou ◽  
Marie L. Tiadé ◽  
Annita A. Hounsa ◽  
Simone K. Malik ◽  
Madikiny Coulibaly ◽  
...  

Hypertension affects more than a quarter of the world adult population, with ruralurban disparities. In Côte d’Ivoire, the prevalence was 21.7% in 2005. The aim of this study was to determine factors associated with hypertension in a peri-urban community in Abidjan. A cross-sectional study was conducted at Anonkoi 3 a peri-urban area in Abidjan. The sample was of 360 subjects aged 18 and older. Behavioral, anthropometric and blood pressure characteristics were determined using WHO STEPS questionnaire and multivariate logistic regression was performed. Prevalence of hypertension was 18.61%. Subjects were low fruit and vegetable consumption (3.3%), low level of physical activity (64.2%) and abdominal obesity at 40%. The risk of hypertension was significant from age 45, in subjects living with a partner and in those with low level of physical activity. Health education programs are essential to prevent cardiovascular risks.


2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Richard K. M’Bra ◽  
Brama Kone ◽  
Yapi G. Yapi ◽  
Kigbafori D. Silué ◽  
Ibrahima Sy ◽  
...  

2021 ◽  
Vol 15 (12) ◽  
pp. e0010004
Author(s):  
Bi Zamble H. Zamble ◽  
Serge S. Yao ◽  
Akré M. Adja ◽  
Mahfoud Bakli ◽  
Dounin D. Zoh ◽  
...  

Background Culex mosquitoes are vectors for a variety of pathogens of public health concern. New indicators of exposure to Culex bites are needed to evaluate the risk of transmission of associated pathogens and to assess the efficacy of vector control strategies. An alternative to entomological indices is the serological measure of antibodies specific to mosquito salivary antigens. This study investigated whether the human IgG response to both the salivary gland extract and the 30 kDa salivary protein of Culex quinquefasciatus may represent a proxy of human exposure to Culex bites. Methodology/Principal findings A multidisciplinary survey was conducted with children aged 1 to 14 years living in neighborhoods with varying exposure to Culex quinquefasciatus in the city of Bouaké, Côte d’Ivoire. Children living in sites with high exposure to Cx quinquefasciatus had a significantly higher IgG response to both salivary antigens compared with children living in the control site where only very few Culex were recorded. Moreover, children from any Culex-high exposed sites had significantly higher IgG responses only to the salivary gland extract compared with children from the control village, whereas no difference was noted in the anti-30 kDa IgG response. No significant differences were noted in the specific IgG responses between age and gender. Sites and the use of a bed net were associated with the level of IgG response to the salivary gland extract and to the 30 kDa antigen, respectively. Conclusions/Significance These findings suggest that the IgG response to Culex salivary gland extracts is suitable as proxy of exposure; however, the specificity to the Culex genus needs further investigation. The lower antigenicity of the 30 kDa recombinant protein represents a limitation to its use. The high specificity of this protein to the Culex genus makes it an attractive candidate and other specific antibody responses might be more relevant as a biomarker of exposure. These epidemiological observations may form a starting point for additional work on developing serological biomarkers of Culex exposure.


2019 ◽  
Vol 13 (4) ◽  
pp. 369-374
Author(s):  
A. Yao ◽  
A. Hué ◽  
J. Danho ◽  
P. Koffi-Dago ◽  
M. Sanogo ◽  
...  

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