scholarly journals Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0196387 ◽  
Author(s):  
Ross A. Carson ◽  
Anthony C. Rudine ◽  
Serena J. Tally ◽  
Alexis L. Franks ◽  
Krystle A. Frahm ◽  
...  
2011 ◽  
Vol 28 (1) ◽  
pp. 196-205 ◽  
Author(s):  
Bingyang Shi ◽  
Lei Deng ◽  
Xiaolin Shi ◽  
Sheng Dai ◽  
Hu Zhang ◽  
...  

2019 ◽  
Vol 12 ◽  
pp. 117906601983696 ◽  
Author(s):  
Elle Koren ◽  
Yaron Fuchs

Although much is known regarding intestinal stem cell (ISC) self-renewal and differentiation, the specific mechanisms used for their elimination is unclear. We recently discovered that the pro-apoptotic protein ARTS, a Septin4 isoform, interacts with X-linked inhibitor of apoptosis (XIAP) in the ISC niche to regulate stem cell survival during intestinal homeostasis and regeneration. These findings point to an intriguing avenue of translational research, examining how manipulation of stem cell apoptosis through the ARTS/XIAP module can affect stem-cell-dependent processes.


PLoS ONE ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. e15341 ◽  
Author(s):  
Muly Tham ◽  
Srinivas Ramasamy ◽  
Hui Theng Gan ◽  
Ashray Ramachandran ◽  
Anuradha Poonepalli ◽  
...  

2017 ◽  
Vol 289 ◽  
pp. 96-102 ◽  
Author(s):  
Amit K. Srivastava ◽  
Sarah K. Gross ◽  
Akshata A. Almad ◽  
Camille A. Bulte ◽  
Nicholas J. Maragakis ◽  
...  

Stem Cells ◽  
2014 ◽  
Vol 32 (6) ◽  
pp. 1636-1648 ◽  
Author(s):  
Srinivas Ramasamy ◽  
Fenggang Yu ◽  
Yuan Hong Yu ◽  
Hariharan Srivats ◽  
Gavin Stewart Dawe ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (15) ◽  
pp. 8315-8325 ◽  
Author(s):  
Zhiping Qi ◽  
Wenlai Guo ◽  
Shuang Zheng ◽  
Chuan Fu ◽  
Yue Ma ◽  
...  

The mammalian central nervous system has a limited ability for self-repair under injury conditions.


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