scholarly journals Persistence of symptoms and quality of life at 35 days after hospitalization for COVID-19 infection

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243882
Author(s):  
Laurie G. Jacobs ◽  
Elli Gourna Paleoudis ◽  
Dineen Lesky-Di Bari ◽  
Themba Nyirenda ◽  
Tamara Friedman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Active Role ◽  
Mental Function ◽  
Clinical Services ◽  
Community Based ◽  
Lower Odds ◽  
Persistent Symptoms ◽  
Muscular Pain ◽  
Community Based Services

Background Characterizing the prevalence and persistence of symptoms associated with COVID-19 infection following hospitalization and their impact is essential to planning post-acute community-based clinical services. This study seeks to identify persistent COVID-19 symptoms in patients 35 days post-hospitalization and their impact on quality of life, health, physical, mental, and psychosocial function. Methods and findings This prospective cohort study used the PROMIS® Instruments to identify symptoms and quality of life parameters in consecutively enrolled patients between March 22 and April 16, 2020, in New Jersey. The 183 patients (median age 57 years; 61.5% male, 54.1% white) reported persistent symptoms at 35 days, including fatigue (55.0%), dyspnea (45.3%), muscular pain (51%), associated with a lower odds rating general health (41.5%, OR 0.093 [95% CI: 0.026, 0.329], p = 0.0002), quality of life (39.8%; OR 0.116 [95% CI: 0.038, 0.364], p = 0.0002), physical health (38.7%, OR 0.055 [95% CI: 0.016, 0.193], p <0.0001), mental health (43.7%, OR 0.093 [95% CI: 0.021, 0.418], p = 0.0019) and social active role (38.7%, OR 0.095 [95% CI: 0.031, 0.291], p<0.0001), as very good/excellent, particularly adults aged 65 to 75 years (OR 8·666 [95% CI: 2·216, 33·884], p = 0·0019). Conclusions COVID-19 symptoms commonly persist to 35 days, impacting quality of life, health, physical and mental function. Early post-acute evaluation of symptoms and their impact on function is necessary to plan community-based services.

scholarly journals Impact of Biofilms on Quality of Life of Rhinosinusitis Patients after Endoscopic Sinus Surgery

2012 ◽  
Vol 5 (3) ◽  
pp. 95-102
Author(s):  
Neelima Gupta ◽  
PP Singh ◽  
Lakshmi Vaid ◽  
Manish Arya ◽  
Rumpa Saha
Keyword(s):  
Quality Of Life ◽  
Surgical Outcomes ◽  
Endoscopic Sinus Surgery ◽  
Active Role ◽  
Sinus Surgery ◽  
Treatment Modalities ◽  
Mucosal Inflammation ◽  
Persistent Symptoms ◽  
Positive Bacterial Culture

ABSTRACT Introduction The chronic and recalcitrant nature of rhinosinusitis has been known from many years. Many reasons for this have been implicated and biofilms have now been established as one of the cause for its recurrent and persistent nature. Little literature and studies exist confirming this effect. This study presents analysis of sinonasal mucosal samples and correlates presence of biofilms with surgical outcomes. Materials and methods An analysis of mucosal samples collected during endoscopic sinus surgery from 40 patients of chronic rhinosinusitis (CRS) was done. Preoperative symptoms, endoscopic and radiological scores were documented and mucosal samples collected intraoperatively were sent for biofilm detection. Biofilm detection was performed using microtiter plate method. Postoperatively patients were followed up for minimum of 3 months with endoscopic evaluation and presence of ongoing symptoms was also recorded. Results Thirteen patients out of 40 patients showed positive bacterial culture. Eight out of 13, i.e. 61.53% bacteria produced biofilms and five out of 13, i.e. 38.46% bacteria did not produce biofilms. Patients with biofilms had significantly worse preoperative and postoperative symptom and endoscopic scores. Thus, presence of biofilms was related to poor outcomes. Conclusion This study showed that the presence of biofilms was correlated with higher symptom scores and poorer surgical outcomes. Also, more recurrences were found in patients with positive biofilms. This strengthens the belief that biofilms may play an active role in persisting mucosal inflammation and persistent symptoms in some patients of CRS. Treatment modalities aiming removal of biofilms may be important in management of CRS. How to cite this article Vaid L, Arya M, Gupta N, Singh PP, Saha R. Impact of Biofilms on Quality of Life of Rhinosinusitis Patients after Endoscopic Sinus Surgery. Clin Rhinol An Int J 2012;5(3):95-102.

Towards a comprehensive telecardiology monitoring centre for community-based services

1997 ◽  
Vol 3 (1_suppl) ◽  
pp. 60-62 ◽  
Author(s):  
D Shanit ◽  
R A Greenbaum
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Primary Care ◽  
General Practitioner ◽  
Pilot Study ◽  
Community Based ◽  
Monitoring Centre ◽  
Accident And Emergency ◽  
Community Based Services

In a pilot study of primary-care telecardiology, 2563 consultations were carried out over 18 months. Following teleconsultation, 2076 patients (81%) were found to be suitable for management entirely by the general practitioner, without the need for referral to hospital. The system identified 487 patients (19%) with cardiac problems who required either admission to hospital or outpatient assessment. There was a resultant saving of referrals to hospital accident and emergency departments. Extension of the telecardiology service to include tele-echocardiography may result in faster access to diagnosis and better management of patients in heart failure, improving patients’ quality of life and reducing hospitalization.

scholarly journals P3-390: The importance of home-and community-based services to quality of life in persons with dementia

2011 ◽  
Vol 7 ◽  
pp. S640-S640
Author(s):  
Lindsay Schwartz ◽  
Judith Kasper ◽  
Betty Black ◽  
Peter Rabins
Keyword(s):  
Quality Of Life ◽  
Community Based ◽  
Community Based Services

Health releated quality of life in irritable bowel syndrome: A community based study+

2001 ◽  
Vol 120 (5) ◽  
pp. A634-A634 ◽  
Author(s):  
K OLDEN ◽  
W CHEY ◽  
J BOYLE ◽  
E CARTER ◽  
L CHANG
Keyword(s):  
Quality Of Life ◽  
Irritable Bowel Syndrome ◽  
Community Based ◽  
Irritable Bowel

scholarly journals Impact and cost-effectiveness evaluation of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss: study protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Xin Ye ◽  
Dawei Zhu ◽  
Siyuan Chen ◽  
Xuefeng Shi ◽  
Rui Gong ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Cost Effectiveness ◽  
Treatment Group ◽  
Hearing Aids ◽  
Control Group ◽  
Chinese Adults ◽  
Community Based ◽  
The Impact

Abstract Background Hearing loss is quite prevalent and can be related to people’s quality of life. To our knowledge, there are limited studies assessing the efficacy of hearing interventions on quality of life in adults. Therefore, we aim to conduct a randomized controlled trial (RCT) to determine the impact and cost-effectiveness of community-based hearing rehabilitation on quality of life among Chinese adults with hearing loss. Methods/design In this two-arm feasibility study, participants aged 16 and above with some degree of hearing loss (n = 464) will be recruited from Linyi City, Shandong Province. They are randomly assigned to the treatment group or the control group. Those in the treatment group are prescribed with hearing aids, while those in the control group receive no intervention. Reinstruction in use of devices is provided for the treatment group during booster visits held 12 months post-randomization or unscheduled interim visits when necessary. Data are collected at baseline and the follow-up 20 months later. The primary outcome is changes in quality of life over a 20-month study period. Secondary outcomes include sub-dimensions in quality of life, physical functioning, chronic diseases, cognitive function, depression, social support, hospitalizations, falls, and healthcare costs. Finally, we will evaluate whether hearing aids intervention is cost-effective to apply in a large scale. Discussion The trial is designed to evaluate the impact and cost-effectiveness of a community-based rehabilitation intervention on quality of life among Chinese adults with hearing loss. We hope that it would help improve the well-being for Chinese adults and provide references in policy and practice for China and other countries. Trial registration Chinese Clinical Trial Registry ChiCTR1900024739. Registered on 26 July 2019.

scholarly journals What’s going on following acute covid-19? Clinical characteristics of patients in an out-patient rehabilitation program

2021 ◽  
pp. 1-12
Author(s):  
Sergiu Albu ◽  
Nicolas Rivas Zozaya ◽  
Narda Murillo ◽  
Alberto Garcia-Molina ◽  
Cristian Andres Figueroa Chacón ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Acute Infection ◽  
Rehabilitation Program ◽  
Neuropsychological Impairment ◽  
Outpatient Rehabilitation ◽  
Screening Process ◽  
Icu Patients ◽  
Persistent Symptoms

BACKGROUND: Coronavirus disease 2019 (COVID-19) patients present long-lasting physical and neuropsychological impairment, which may require rehabilitation. OBJECTIVES: The current cross-sectional study characterizes post COVID-19 sequelae and persistent symptoms in patients in an outpatient rehabilitation program. METHODS: Thirty patients [16 post-ICU and 14 non-ICU; median age = 54(43.8–62) years; 19 men] presenting sequelae and/or persistent symptoms (>3 months after acute COVID-19) were selected of 41 patients referred for neurorehabilitation. Patients underwent physical, neuropsychological and respiratory evaluation and assessment of impact of fatigue and quality of life. RESULTS: The main reasons for referral to rehabilitation were: fatigue (86.6%), dyspnea (66.7%), subjective cognitive impairment (46.7%) and neurological sequelae (33.3%). Post-ICU patient presented sequelae of critical illness myopathy and polyneuropathy, stroke and encephalopathy and lower forced vital capacity compared to non-ICU patients. Cognitive impairment was found in 63.3% of patients, with a similar profile in both sub-groups. Increased physical fatigue, anxiety and depression and low quality of life were prevalent irrespective of acute COVID-19 severity. CONCLUSIONS: The variability of post COVID-19 physical and neuropsychological impairment requires a complex screening process both in ICU and non-ICU patients. The high impact of persistent symptoms on daily life activities and quality of life, regardless of acute infection severity, indicate need for rehabilitation.

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