Fracture incidence in adults in relation to age and gender: A study of 27,169 fractures in the Swedish Fracture Register in a well-defined catchment area

Studies on fracture incidence have mostly been based on retrospectively registered data from local hospital databases. The Swedish Fracture Register (SFR) is a national quality register collecting data prospectively on fractures, at the time of care-seeking. In the present study the incidence of all different fractures, regardless of location, in adults’ ≥ 16 years treated at the only care provider for patients with fractures within a catchment area of approximately 550,000 inhabitants, during 2015‒2018 are described. Age, gender, and fracture location (according to AO/OTA classification) was used for the analyses and presentation of fracture incidences. During the 4-year study period, 23,917 individuals sustained 27,169 fractures. The mean age at fracture was 57.9 years (range 16‒105 years) and 64.5% of the fractures occurred in women. The five most common fractures accounted for more than 50% of all fractures: distal radius, proximal femur, ankle, proximal humerus, and metacarpal fractures. Seven fracture incidence distribution groups were created based on age- and gender-specific incidence curves, providing visual and easily accessible information on fracture distribution. This paper reports on incidence of all fracture locations based on prospectively collected data in a quality register. The knowledge on fracture incidence related to age and gender may be of importance for the planning of orthopaedic care, involving both in- and out-patients as well as allocating surgical resources. Further, this might be useful for organizing preventive measures, especially in countries with similar socioeconomic structure and fracture burden.

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Impact of comorbidity, age, and gender on seasonal variation in hip fracture incidence. A NOREPOS study

Archives of Osteoporosis ◽

10.1007/s11657-014-0191-2 ◽

2014 ◽

Vol 9 (1) ◽

Cited By ~ 13

Author(s):

Siri M. Solbakken ◽

Jeanette H. Magnus ◽

Haakon E. Meyer ◽

Nina Emaus ◽

Grethe S. Tell ◽

...

Keyword(s):

Seasonal Variation ◽

Hip Fracture ◽

Fracture Incidence ◽

Age And Gender ◽

Hip Fracture Incidence ◽

And Gender

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Risk of serious infections in patients with rheumatoid arthritis treated in routine care with abatacept, rituximab and tocilizumab in Denmark and Sweden

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2018-214326 ◽

2019 ◽

Vol 78 (3) ◽

pp. 320-327 ◽

Cited By ~ 16

Author(s):

Kathrine Lederballe Grøn ◽

Elizabeth V Arkema ◽

Bente Glintborg ◽

Frank Mehnert ◽

Mikkel Østergaard ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Routine Care ◽

Incidence Rates ◽

Age And Gender ◽

Reactive Protein ◽

Relative Risks ◽

Quality Register ◽

Inverse Variance ◽

Serious Infections ◽

And Gender

ObjectiveTo estimate (1) crude and age-and gender-adjusted incidence rates (IRs) of serious infections (SI) and (2) relative risks (RR) of SI in patients with rheumatoid arthritis (RA) initiating treatment with abatacept, rituximab or tocilizumab in routine care.MethodsThis is an observational cohort study conducted in parallel in Denmark and Sweden including patients with RA in Denmark (DANBIO) and Sweden (Anti-Rheumatic Treatment in Sweden Register/Swedish Rheumatology Quality Register) who started abatacept/rituximab/tocilizumab in 2010–2015. Patients could contribute to more than one treatment course. Incident SI (hospitalisations listing infection) and potential confounders were identified through linkage to national registries. Age- and gender-adjusted IRs of SI per 100 person years and additionally adjusted RRs of SI during 0–12 and 0–24 months since start of treatment were assessed (Poisson regression). Country-specific RRs were pooled using inverse variance weighting.ResultsWe identified 8987 treatment courses (abatacept: 2725; rituximab: 3363; tocilizumab: 2899). At treatment start, rituximab-treated patients were older, had longer disease duration and more previous malignancies; tocilizumab-treated patients had higher C reactive protein. During 0–12 and 0–24 months of follow-up, 456 and 639 SI events were identified, respectively. The following were the age- and gender-adjusted 12-month IRs for abatacept/rituximab/tocilizumab: 7.1/8.1/6.1 for Denmark and 6.0/6.4/4.7 for Sweden. The 24-month IRs were 6.1/7.5/5.2 for Denmark and 5.6/5.8/4.3 for Sweden. Adjusted 12-month RRs for tocilizumab versus rituximab were 0.82 (0.50 to 1.36) for Denmark and 0.76 (0.57 to 1.02) for Sweden, pooled 0.78 (0.61 to 1.01); for abatacept versus rituximab 0.94 (0.55 to 1.60) for Denmark and 0.86 (0.66 to 1.13) for Sweden, pooled 0.88 (0.69 to 1.12); and for abatacept versus tocilizumab 1.15 (0.69 to 1.90) for Denmark and 1.14 (0.83 to 1.55) for Sweden, pooled 1.13 (0.91 to 1.42). The adjusted RRs for 0–24 months were similar.ConclusionFor patients starting abatacept, rituximab or tocilizumab, differences in baseline characteristics were seen. Numerical differences in IR of SI between drugs were observed. RRs seemed to vary with drug (tocilizumab < abatacept < rituximab) but should be interpreted with caution due to few events and risk of residual confounding.

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Pediatric Distal Forearm Fracture Epidemiology in Malmö, Sweden—Time Trends During Six Decades

Journal of Wrist Surgery ◽

10.1055/s-0039-1692471 ◽

2019 ◽

Vol 08 (06) ◽

pp. 463-469 ◽

Cited By ~ 2

Author(s):

Vasileios Lempesis ◽

Daniel Jerrhag ◽

Björn E. Rosengren ◽

Lennart Landin ◽

Carl Johan Tiderius ◽

...

Keyword(s):

Time Trends ◽

Traffic Accidents ◽

Sports Injuries ◽

Forearm Fracture ◽

Fracture Incidence ◽

Patient Specific ◽

Distal Forearm ◽

Distal Forearm Fracture ◽

Age And Gender ◽

And Gender

Abstract Background The distal forearm fracture is the most common fracture in children. To allocate health care resources and evaluate if prevention strategies have been successful, it is essential to monitor changes in the epidemiology of common fractures. Methods Our hospital serves a city in which year 2006 included 276,244 inhabitants (49,664 <17 years of age). Through the hospital archives, we identified fractures sustained by individuals younger than 16 years during 2005 and 2006 and compared these with previous collected and published data from the same area and hospital for the period 1950 to 1994. We used official population data to estimate period-specific fracture rates and age and gender standardized time trends. We report rates as number of fractures per 100,000 person-years and changes between periods as rate ratios (RR) with 95% confidence intervals (CIs). Results We identified 521 distal forearm fractures, corresponding to a crude fracture incidence of 564/100,000 person-years (boys 719; girls 401). Age-adjusted fracture incidence was 70% higher in boys than in girls (RR 1.7; 95% CI 1.3–2.3). The age- and gender-adjusted hand fracture incidence was 40% higher in 2005–2006 than in 1950/1955 (RR 1.4; 95% CI 1.2 to 1.8) but no higher than 1993–1994 (RR 1.1; 95% CI 0.9–1.3). Fracture etiology of 2005 to 2006 included sports injuries in 41% and traffic accidents in 11% of the cases, while sports injuries explained 37% and traffic accidents 18% in 1950 to 1955. Conclusion In 2005 to 2006, we found higher rates in boys and higher overall rates compared with the 1950s but no significant differences compared with the rates in 1993 to 1994. Future studies should include patient-specific data to unravel causal factors. Level of evidence This is a Level III b study.

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Psychotic illness in ethnic minorities: clarification from the 1991 census

Psychological Medicine ◽

10.1017/s0033291700033845 ◽

1996 ◽

Vol 26 (1) ◽

pp. 203-208 ◽

Cited By ~ 99

Author(s):

J. Van Os ◽

D. J. Castle ◽

N. Takei ◽

G. Der ◽

R. M. Murray

Keyword(s):

Ethnic Minority ◽

Catchment Area ◽

Common Factor ◽

Minority Populations ◽

Psychotic Illness ◽

Age And Gender ◽

Affective Psychosis ◽

Admission Rates ◽

African Group ◽

And Gender

SynopsisAge and sex-adjusted first admission rates for operationally-defined schizophrenia and other non-affective psychosis in different ethnic groups were calculated over the period 1988–1992 in a defined catchment area in South London. Standardized rates for schizophrenia, corrected for age- and gender-related under-reporting in the 1991 census and a 20% underestimate of the size of the ethnic minority populations in the area, were not only higher in the Afro-Caribbean group (SMR: 3·1; 95% Cl: 2·0–4·7), but also in the African group (SMR: 4·2; 95% Cl: 2·8–6·2). It was further found that higher rates were not specific to schizophrenia. These findings suggest that some common factor associated with ethnic minority membership is important in producing an excess of psychotic illness.

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