scholarly journals Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247865
Author(s):  
Gizem Alkurt ◽  
Ahmet Murt ◽  
Zeki Aydin ◽  
Ozge Tatli ◽  
Nihat Bugra Agaoglu ◽  
...  

COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Non-pandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in “high risk” group had similar seropositivity rate with “no risk” group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.

Author(s):  
Gizem ALKURT ◽  
Ahmet MURT ◽  
Zeki AYDIN ◽  
Ozge TATLI ◽  
Nihat Bugra AGAOGLU ◽  
...  

COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Non-pandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in high risk group had similar seropositivity rate with no risk group (2.9 vs 3.6 p=0.7), indicating the efficient implementation of protection measures in the hospitals in Turkey. These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.


Psicologia ◽  
2021 ◽  
Vol 35 (1) ◽  
pp. 163-173
Author(s):  
Inês Carneiro Sousa ◽  
Teresa Almeida ◽  
Catarina Correia Leal

The COVID-19 pandemic poses critical challenges for the health care workers (HCWs) around the world due to the increasing demands imposed on health care systems. This study aims to investigate how risk concern impacts burnout via positive and negative affect. Further, the moderating role of risk exposure (low, medium, and high) in this parallel mediation model is examined. A sample of 257 Portuguese HCWs answered a questionnaire. Structural equation modeling (SEM) analysis was applied. Results showed that risk concern positively influences negative affect – but not positive affect – and, consequently, burnout. Contrary to our expectations, this indirect effect was not greater for individuals in the high-risk group (vs. low-risk group), which can be explained by individual and organizational factors' buffering role. These findings draw healthcare organizations' attention to the hazardous effects of risk concern on HCWs' well-being.


2018 ◽  
Vol 19 (2) ◽  
pp. 80-83 ◽  
Author(s):  
Hoda Alhamoudi ◽  
Nawras Alhalabi ◽  
Mouhammed Zein ◽  
Nazir Ibrahim

2021 ◽  
Author(s):  
Jessy S J ◽  
Shamha Beegum ◽  
Genga Gopakumar ◽  
Bindu G ◽  
Chntha S ◽  
...  

Back ground and objectives- This study was undertaken to estimate the prevalence of SARS-CoV-2 infection among Health care workers [HCWs] of a hybrid COVID treatment hospital in Kerala. Methods- The study was conducted during 3rd week of January 2021. Among 3550 HCWs, 979 subjects were selected by stratified random sampling and grouped into high risk and low risk category based on job setting. Demographic details and clinical information regarding previous history of COVID 19 were collected at the time of SARS-CoV-2 IgG testing. Results: From 979 subjects, the data with respect to 940 health care workers were analysed. SARS-CoV-2 IgG was detected in 19.1% of HCWs. Seroprevalence among high risk group was 20.3% and that in low risk group was 7.4% [p=0.005]. In high-risk group, seropositivity was noted in 30.54 % of nurses, 19% hospital attenders, 18.9% resident doctors and 6.4% consultant doctors. In those with past history of SARS-CoV-2 infection, seropositivity was 75.4%. In those who were COVID positive during July2020, 33.3% were still IgG reactive. Interpretation and conclusion- The study reported 19.1% SARS CoV-2 IgG reactivity among health care workers in our hospital. Seropositivity was significantly higher in high risk group compared to low risk group. Antibody decay kinetics in our study is comparable to that in published literature. Infection control challenges in hybrid hospitals account for higher seropositivity in this study compared to overall seroprevalence among HCWs in Kerala.


2020 ◽  
Vol 90 (3) ◽  
Author(s):  
Nishanth Dev ◽  
Vijay Kumar ◽  
Jhuma Sankar

To the Editor, The new pandemic COVID -19 caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) is a global threat. So far, more than 11 million infections and more than five hundred thousand deaths have been reported worldwide. In India the number of cases as of 5th July, 2020 is 6,73,165 with 19,268 deaths. Health care workers (HCWs) have been the backbone of this pandemic since the very beginning...


2021 ◽  
Vol 7 (1) ◽  
pp. 1-9
Author(s):  
Oyunsuren D

The new SARS-n-CoV2 (COVID-19) pandemic is a global threat to the mental, physical and social health of the population.


Author(s):  
Rashmi Negi ◽  
Arti Arti

Background: Since December 2019, a novel coronavirus disease (COVID-19) began its journey around the world. The novel Coronavirus (2019-nCoV, officially known as SARS-CoV-2 or COVID-19) was first reported in December 2019, as a cluster of acute respiratory illness in Wuhan, Hubei Province, China, from where it spread rapidly to over 198 countries. It was declared as a global pandemic by WHO on 12th March 2020.Coronavirus disease (COVID-19) is a highly transmittable infection and India due to its geographical location is vulnerable to a worst outbreak. India is suddenly increasing its hike in number of positive cases including number of healthcare professionals (HCPs) also acquired infection. Therefore, the aim of study is to assess knowledge and perception among health care workers in Delhi NCR, a vulnerable region, regarding COVID-19. Method: A web-based, cross-sectional study was conducted using a survey instrument to obtain responses from health care workers in Delhi NCR region. A 45-item survey instrument was developed using course materials available on WHO’s website on emerging COVID-19. The survey covered health care workers socio demographic profile, awareness, information sources, and knowledge and perceptions related to COVID-19. Result: The study findings suggest that the level of knowledge was good among health care workers and overall a positive perception was found about COVID 19. Conclusion: As the global threat of COVID-19 continues to emerge, greater efforts through educational campaigns that target HCWs and the wider population beyond borders are needed.


2020 ◽  
pp. 101053952097730
Author(s):  
Nishant Kumar ◽  
Shibal Bhartiya ◽  
Shashank Desai ◽  
Amit Mutha ◽  
Amit Beldar ◽  
...  

Aim To ascertain the seroprevalence of antibodies against SARS-CoV-2 among health care workers in tertiary care hospitals in Mumbai, India. Methods Health care workers (801) from designated COVID-19 hospitals (400) and non–COVID-19 facilities (401) underwent an electrochemiluminescent automated immunoassay for antibodies to SARS-CoV-2. Details including demographics, comorbidities, symptoms compatible with COVID-19, contact with COVID-19 individuals, personal protective equipment use at work, and details of polymerase chain reaction tests were collected through a validated questionnaire. Results Doctors (201, 25.1%), nurses (308, 38.5%), and ancillary workers (292, 36.5%) participated in the study. Seroprevalence in 801 participants was 11.1% (9.1% to 13.5%). It was significantly higher ancillary workers (18.5%, 14.5% to 23.3%) than doctors (7%, 4.2% to 11.4%) and nurses (6.8%, 4.5% to 10.2%). Seroprevalence was significantly higher in non–COVID-19 hospitals (13.5%, 10.5% to 17.2%) than COVID-19 hospitals (8.7%, 6.3% to 11.9%). Having a COVID-19 household contact was a significant risk for seropositivity (18.9% vs 10.3%), while a neighborhood contact did not affect seropositivity (9.4% vs 7.3%). Loss of taste/smell and fever were only 2 symptoms associated with seropositivity. Comorbidities did not affect the seropositivity rate. Conclusion Seropositivity was likely to be higher in ancillary workers and in non-COVID hospitals. There is need to enhance COVID protection protocols and awareness among all health care workers.


2021 ◽  
Author(s):  
AWADHESH KUMAR SINGH ◽  
Sanjeev Ratnakar Phatak ◽  
RITU SINGH ◽  
Kingshuk Bhattacharjee ◽  
Nagendra Kumar Singh ◽  
...  

Background: We assessed the humoral immune response after the completion of two doses of both ChAdOx1-nCOV (CovishieldTM) and BBV-152 (CovaxinTM) vaccines in Indian health care workers (HCW). Methods: A Pan-India, Cross-sectional, Coronavirus Vaccine-induced Antibody Titre (COVAT) study was conducted that measured SARS-CoV-2 anti-spike binding antibody quantitatively, 21 days or more after the first and second dose of two vaccines in both severe acute respiratory syndrome (SARS-CoV-2) naive and recovered HCW. Primary aim was to analyze antibody response (seropositivity rate and median [inter-quartile range, IQR] antibody titre) following each dose of both vaccines and its correlation to age, sex, blood group, body mass index (BMI) and comorbidities. Here we report the final results of anti-spike antibody response after the two completed doses. Results: Among the 515 HCW (305 Male, 210 Female), 95.0% showed seropositivity after two doses of both vaccines. Of the 425 Covishield and 90 Covaxin recipients, 98.1% and 80.0% respectively, showed seropositivity. However, both seropositivity rate and median (IQR) rise in anti-spike antibody was significantly higher in Covishield vs. Covaxin recipient (98.1 vs. 80.0%; 127.0 vs. 53 AU/mL; both p<0.001). This difference persisted in 457 SARS-CoV-2 naive cohorts and propensity-matched (age, sex and BMI) analysis of 116 cohorts. While no difference was observed in relation to sex, BMI, blood group and any comorbidities; people with age >60 years or those with type 2 diabetes had a significantly lower seropositivity rates. Both vaccine recipients had similar solicited mild to moderate adverse events and none had severe or unsolicited side effects. In SARS-CoV-2 naive cohorts, sex, presence of comorbidities, and vaccine type were independent predictors of antibody positivity rate in multiple logistic regression analysis. Conclusions: Both vaccines elicited good immune response after two doses, although seropositivity rates and median anti-spike antibody titre was significantly higher in Covishield compared to Covaxin arm.


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