Murine Cerebrovascular Cells as a Cell Culture Model for Cerebral Amyloid Angiopathy: Isolation of Smooth Muscle and Endothelial Cells From Mouse Brain

2005 ◽  
pp. 211-220
Author(s):  
Sonia S. Jung ◽  
Efrat Levy
2018 ◽  
Vol 225 ◽  
pp. 309-318 ◽  
Author(s):  
Dagmar Brislinger ◽  
Christine Daxböck ◽  
Eva Roßmanith ◽  
Manuela Stückler ◽  
Ingrid Lang ◽  
...  

1991 ◽  
Vol 54 (2) ◽  
pp. 159-171 ◽  
Author(s):  
Lisa K. Minor ◽  
Florence H. Mahlberg ◽  
W. Gray Jerome ◽  
Jon C. Lewis ◽  
George H. Rothblat ◽  
...  

2003 ◽  
Vol 983 (1-2) ◽  
pp. 48-57 ◽  
Author(s):  
Bozena Mazur-Kolecka ◽  
Dagmar Kowal ◽  
Tirasak Sukontasup ◽  
Dennis Dickson ◽  
Janusz Frackowiak

1991 ◽  
Vol 115 (6) ◽  
pp. 1725-1735 ◽  
Author(s):  
L L Rubin ◽  
D E Hall ◽  
S Porter ◽  
K Barbu ◽  
C Cannon ◽  
...  

Endothelial cells that make up brain capillaries and constitute the blood-brain barrier become different from peripheral endothelial cells in response to inductive factors found in the nervous system. We have established a cell culture model of the blood-brain barrier by treating brain endothelial cells with a combination of astrocyte-conditioned medium and agents that elevate intracellular cAMP. These cells form high resistance tight junctions and exhibit low rates of paracellular leakage and fluid-phase endocytosis. They also undergo a dramatic structural reorganization as they form tight junctions. Results from these studies suggest modes of manipulating the permeability of the blood-brain barrier, potentially providing the basis for increasing the penetration of drugs into the central nervous system.


2010 ◽  
Vol 90 (12) ◽  
pp. 1770-1781 ◽  
Author(s):  
Robert C Huebert ◽  
Kumaravelu Jagavelu ◽  
Ann F Liebl ◽  
Bing Q Huang ◽  
Patrick L Splinter ◽  
...  

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