scholarly journals Water-Mediated Ceric Ammonium Nitrate Catalyzed C-C/C-N Bond Formation: Convenient Access to Polyfunctionalized Pyrazoles via Multicomponent Reaction

2019 ◽  
Vol 31 (5) ◽  
pp. 1189-1194 ◽  
Author(s):  
Vikas D. Kadu ◽  
Mahesh G. Hublikar ◽  
Dattatraya G. Raut ◽  
Raghunath B. Bhosale
Keyword(s):  
Polyethylene Glycol ◽  
Ammonium Nitrate ◽  
Aqueous Medium ◽  
Multicomponent Reaction ◽  
Bond Formation ◽  
Dual Role ◽  
Ceric Ammonium Nitrate ◽  
Role Of Solvent ◽  
Convenient Access

An efficient multicomponent approach has been developed in the environmentally green aqueous medium for synthesis of substituted polyfunctionalized pyrazoles. The simple and readily available aldehydes, malononitrile and phenylhydrazines substrates afforded polysubstituted imidazoles (15 examples) up to 96 % yield. The polyethylene glycol is playing the dual role of solvent and promoter with water in this reaction catalyzed by ceric ammonium nitrate.

Revisiting the Synthesis of Aryl Nitriles: A pivotal role of CAN

2021 ◽  
Author(s):  
Rakhee Saikia ◽  
Kwihwan Park ◽  
Hayato Masuda ◽  
Miki Itoh ◽  
Tsuyoshi Yamada ◽  
...  
Keyword(s):  
Ammonium Nitrate ◽  
Cost Effective ◽  
Dual Role ◽  
Ceric Ammonium Nitrate ◽  
Pivotal Role ◽  
Aryl Iodides ◽  
Cost Effective Approach ◽  
Aryl Nitriles

Facilitated by the dual role of Ceric Ammonium Nitrate (CAN), herein we report a cost-effective approach for the cyanation of aryl iodides/bromides with CAN-DMF as an addition to the existing...

Polyethylene glycol-mediated synthesis of decahydroacridine-1,8-diones catalyzed by ceric ammonium nitrate

2010 ◽  
Vol 64 (6) ◽  
Author(s):  
Mazaahir Kidwai ◽  
Divya Bhatnagar
Keyword(s):  
Polyethylene Glycol ◽  
Ammonium Nitrate ◽  
Effective Medium ◽  
Ceric Ammonium Nitrate ◽  
One Pot ◽  
One Pot Synthesis ◽  
High Yields

AbstractPolyethylene glycol was found to be an inexpensive non-toxic and effective medium for one pot synthesis of high yields of decahydroacridine-1,8-diones in the presence of ceric ammonium nitrate as the catalyst. Moreover, the solvent can be recovered and reused.

Highly efficient regio and diastereoselective synthesis of functionalized bis-spirooxindoles and their antibacterial properties

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26546-26552 ◽  
Author(s):  
Pambala Ramesh ◽  
Kadiyala Srinivasa Rao ◽  
Rajiv Trivedi ◽  
B. Sudheer Kumar ◽  
R. S. Prakasham ◽  
...  
Keyword(s):  
Ammonium Nitrate ◽  
Aqueous Medium ◽  
Antibacterial Properties ◽  
Ceric Ammonium Nitrate ◽  
Diastereoselective Synthesis ◽  
Highly Efficient

A simple, efficient, regioselective and diastereoselective method has been developed for the synthesis of spirooxindole-pyrrolidines using 0.5 mol% of ceric ammonium nitrate in aqueous medium.

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

2021 ◽  
Vol 19 (1) ◽  
pp. 156-161
Author(s):  
Silvia Anselmi ◽  
Siyu Liu ◽  
Seong-Heun Kim ◽  
Sarah M. Barry ◽  
Thomas S. Moody ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Dual Role ◽  
Mild Conditions ◽  
Urea Hydrogen Peroxide ◽  
Role Of Solvent

Sulfoxides have been synthesised from various sulfide substrates under mild conditions exploiting CALB biocatalyst in the presence of urea hydrogen peroxide and AcOEt which acts with the dual role of solvent and reagent.

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