Relationship between fat distribution ratio and blood pressure in obese adolescents

Background The incidence of obesity in big cities increasessignificantly. The association between obesity and increased riskof cardiovascular disease and hypertension in adults has beenknown but less information is available in adolescents. Similarly,the relationship between body-fat distribution and cardiovasculardiseases in adolescents is less clear tha that in adults.Objective This study aimed to determine the association betweenbody fat distribution and increased blood pressure in obeseadolescents in Bandung.Methods This cross-sectional study was conducted from June toAugust 2006. Subjects were students aged 15-18 years at highschools in Bandung with body mass index (BMI) measured usingCDC chart 2000 (> P95) and increased blood pressure (> P90)depended on age and gender according to National High BloodPressure Education Program Working Group on High BloodPressure in Children and Adolescents 2004. Waist-to-hip ratio(central fat), and subscapula skinfold-to-triceps skinfold ratio(peripheral fat) were used to measure fat distribution. Correlationbetween body fat distribution and blood pressure was analyzedusing Pearson correlation statistical test.Results Out of 3170 adolescents examined, 34 obese adolescentgirls and 43 obese adolescent boys had increased blood pressure.Correlation between waist-to-hip ratio and systole blood pressurein boys showed by r=0.495; P=0.003 and girls showed r=0.494;P=O.OOl. Correlation between subscapula skinfold-to-tricepsskinfold ratio in boys showed r=0.289; P=0.097 and girls showedby r=0.248; P=0.109.Conclusion Central fat is moderately correlated with increasedblood pressure in obese adolescents.

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Chronic Kidney Disease Modifies The Relationship Between Body Fat Distribution and Blood Pressure: A Cross-Sectional Analysis

International Journal of Nephrology and Renovascular Disease ◽

10.2147/ijnrd.s247907 ◽

2020 ◽

Vol Volume 13 ◽

pp. 107-118

Author(s):

Cindy George ◽

Tandi E Matsha ◽

Florence E Davidson ◽

Julia H Goedecke ◽

Rajiv T Erasmus ◽

...

Keyword(s):

Blood Pressure ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Body Fat ◽

Fat Distribution ◽

Body Fat Distribution ◽

Cross Sectional ◽

Cross Sectional Analysis ◽

Sectional Analysis ◽

The Relationship

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Serum Immunoreactive Insulin (IRI) and Its Relationship to Obesity, Body Fat Distribution, Blood Pressure and Fasting Blood Glucose in Egyptian Women

Journal of Clinical Biochemistry and Nutrition ◽

10.3164/jcbn.3.117 ◽

1987 ◽

Vol 3 (2) ◽

pp. 117-124

Author(s):

Salwa M. EL-SHEBINI ◽

Laila M. HANNA ◽

Salwa T. TOPOUZADA ◽

Tahany H. MIKHAIL

Keyword(s):

Blood Pressure ◽

Blood Glucose ◽

Body Fat ◽

Fasting Blood Glucose ◽

Fat Distribution ◽

Body Fat Distribution ◽

Immunoreactive Insulin ◽

Serum Immunoreactive Insulin ◽

Egyptian Women

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Hypertension and its Relation with Waist to Hip Ratio in Women Referred to Bojnurd Urban Health Centers in 2014

The Open Hypertension Journal ◽

10.2174/1876526201911010001 ◽

2019 ◽

Vol 11 (1) ◽

pp. 1-5

Author(s):

Hossein Lashkardoost ◽

Fateme Hoseyni ◽

Elham Rabbani ◽

Farzane Q Moqadam ◽

Leila Hosseini ◽

...

Keyword(s):

Blood Pressure ◽

Pearson Correlation ◽

Cross Sectional Study ◽

Health Centers ◽

Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Waist To Hip Ratio ◽

Significant Relationships ◽

Present Cross Sectional Study

Introduction: North Khorasan province has one of the highest rates of hypertension. One of the main causes of hypertension is obesity. Obesity is one of the most important public health problems around the world as a risk factor for non-communicable diseases. Since a similar study was not conducted in Bojnurd, we examined the relationship between waist to hip ratio with hypertension. Methods: The present cross-sectional study was conducted on women referring to Bojnurd health centers. To analyze the data, we used t-test, chi-square, multiple logistic regression and Pearson correlation in Stata 12 software. Results: In this cross-sectional study, the prevalence of systolic blood pressure was 14.78% and diastolic blood pressure was 15.65%. So waist to the hips showed the highest correlation with the changes in hypertension. Conclusion: There are significant relationships between the age and the number of pregnancies with the risk of hypertension. Since a significant percentage of people are unaware of the existence of hypertension, changing diet and having regular physical activity along with social support is an important strategy.

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Pioglitazone improves insulin resistance and decreases blood pressure in adult patients with congenital adrenal hyperplasia

Acta Endocrinologica ◽

10.1530/eje-09-0523 ◽

2009 ◽

Vol 161 (6) ◽

pp. 887-894 ◽

Cited By ~ 7

Author(s):

Jeanne Margot Kroese ◽

Christiaan F Mooij ◽

Marinette van der Graaf ◽

Ad R M M Hermus ◽

Cees J Tack

Keyword(s):

Insulin Resistance ◽

Blood Pressure ◽

Insulin Sensitivity ◽

Body Fat ◽

Matched Control ◽

Fat Distribution ◽

Body Fat Distribution ◽

Adrenal Hyperplasia ◽

Insulin Resistant ◽

Steroid Profiles

ContextPatients with congenital adrenal hyperplasia (CAH) are chronically treated with supraphysiological doses of glucocorticoids, which are known to induce insulin resistance. Thiazolidinediones might reverse this effect and improve insulin sensitivity.ObjectivesTo assess insulin sensitivity in CAH patients and the effect of pioglitazone treatment on insulin sensitivity in CAH patients. Secondary objectives were the effects of treatment with pioglitazone on blood pressure, body fat distribution, lipid, and steroid profiles.DesignRandomized placebo controlled crossover trial.ParticipantsTwelve CAH patients and 12 body mass and age-matched control subjects.InterventionSixteen-week treatment with pioglitazone (45 mg/day) or placebo.Main outcome measureInsulin sensitivity measured by euglycemic clamp and oral glucose tolerance test. Further measures were 24-h blood pressure profiles, body fat distribution measured by magnetic resonance imaging, dual energy x-ray absorptiometry (DEXA) and bioimpedance procedures, liver fat by magnetic resonance spectroscopy, lipid, and steroid profiles.ResultsCAH patients were insulin resistant compared with healthy controls. Treatment with pioglitazone significantly improved insulin sensitivity in CAH patients (glucose infusion rate (GIR) from 28.5±11.6 to 38.9±11.0 μmol/kg per min, P=0.000, GIR in controls 46.2±23.4 μmol/kg per min, P<0.05 versus CAH). Treatment with pioglitazone decreased blood pressure (systolic: 124.0±13.6 vs 127.0±14.9 mmHg, P<0.001, diastolic: 72.8±11.5 vs 77.4±12.6 mmHg, P<0.001). No changes in body fat distribution, lipid, and steroid profiles were observed.ConclusionsCAH patients are insulin resistant compared with matched control subjects. Treatment with pioglitazone improves insulin sensitivity and decreases blood pressure in CAH patients.

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