Efektivitas Azitromisin Untuk Pencegahan Bronchopulmonary Dysplasia pada Bayi Prematur

Ayu Sasmita Rany; Putri Maharani Tristanita Marsubrin

doi:10.14238/sp23.4.2021.270-8

Efektivitas Azitromisin Untuk Pencegahan Bronchopulmonary Dysplasia pada Bayi Prematur

Sari Pediatri ◽

10.14238/sp23.4.2021.270-8 ◽

2021 ◽

Vol 23 (4) ◽

pp. 270

Author(s):

Ayu Sasmita Rany ◽

Putri Maharani Tristanita Marsubrin

Keyword(s):

Bronchopulmonary Dysplasia ◽

Google Scholar ◽

Level Of Evidence

Latar belakang. Bronchopulmonary dysplasia (BPD) merupakan salah satu komplikasi terbanyak pada bayi prematur dan juga merupakan prediktor penting terjadinya gangguan perkembangan. Upaya untuk mencegah BPD penting dilakukan untuk menurunkan angka mortalitas bayi prematur. Tujuan. Mengetahui efektivitas azitromisin dalam pencegahan BPD pada bayi prematur. Metode. Penelusuran pustaka dilakukan secara ekstensif melalui beberapa pangkalan data, yaitu Pubmed, Cochrane, Google scholar, dan EBSCO dengan kata kunci “neonates”, “OR” “newborn”, “AND” “preterm”, “OR” “premature”, “AND” “azithromycin”, “AND” “bronchopulmonary dysplasia”. Hasil. Penelusuran literatur diperoleh 1 artikel yang terpilih kemudian dilakukan telaah kritis, yaitu studi telaah sistematik dan meta-analisis oleh Razak dkk, dengan level of evidence 1a. Studi tersebut menunjukkan bahwa tidak terdapat perbedaan bermakna antara kedua kelompok untuk luaran BPD pada seluruh bayi prematur (RR 0,92, IK 95%, 0,71-1,19, p=0,53). Namun, terdapat perbedaan bermakna antara kelompok yang mendapat azitromisin dan kelompok yang mendapat plasebo atau tidak mendapat terapi untuk luaran angka kematian atau BPD pada bayi prematur dengan Ureaplasma positif (RR 0,83, IK 95%, 0,70-0,99, p=0,04). Durasi penggunaan suplementasi oksigen lebih rendah secara bermakna pada kelompok azitromisin dibandingkan dengan kelompok yang tidak mendapat terapi (rerata perbedaan -6,06%, IK 95%, -7,4 hingga -4,72, p<0,00001). Kesimpulan. Bukti yang didapatkan menunjukkan bahwa pemberian azitromisin tidak terbukti secara bermakna dapat mencegah BPD pada seluruh bayi prematur, tetapi terdapat penurunan risiko BPD atau kematian pada bayi prematur dengan kultur Ureaplasma positif. Dibutuhkan penelitian lebih lanjut untuk menilai efektivitas azitromisin dalam pencegahan BPD pada bayi prematur.

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Uso do modelo Teórico da Organização Sistêmica na avaliação familiar

Revista de Enfermagem UFPE on line ◽

10.5205/1981-8963.2019.242282 ◽

2019 ◽

Vol 13 ◽

Author(s):

Fernanda Lise ◽

Eda Schwartz ◽

Kathryn Hoehn Anderson ◽

Marie Luise Friedemann

Keyword(s):

Family Functioning ◽

Family Health ◽

Google Scholar ◽

Virtual Library ◽

Validity And Reliability ◽

Nursing Theory ◽

Systemic Organization ◽

Level Of Evidence ◽

Family Nursing ◽

Funcionamiento Familiar

Objetivo: produzir um levantamento de estudos sobre a aplicação do modelo teórico da organização sistêmica na avaliação da eficácia do funcionamento familiar e construir o estado da arte. Método: trata-se de estudo bibliográfico, descritivo, do tipo revisão integrativa, entre 2001 a 2017, nas bases de dados MEDLINE, LILACS, Google Scholar e na Biblioteca Virtuais SciELO, com consulta a especialistas via ResearchGate. Resultados: apresentaram-se 21 estudos desenvolvidos por enfermeiros em seis países, nos quais se evidenciaram a validade e a confiabilidade do instrumento ASF-E, avaliando a eficácia do funcionamento familiar, principalmente, em condições crônicas ou de vulnerabilidade. Utilizaram-se metodologia adequada e nível de evidência IV. Conclusão: conclui-se que o modelo teórico da organização sistêmica tem sido utilizado por ser considerado uma ferramenta válida para avaliar a saúde da família na em diferentes contextos de atuação da Enfermagem de famílias. Descritores: Enfermagem Familiar; Família; Enfermagem; Autoeficácia; Teoria de Enfermagem; Revisão.ABSTRACTObjective: to produce a survey of studies on the application of the Framework of Systemic Organization to evaluate the effectiveness of family functioning and build the state of the art. Method: this is a descriptive bibliographic study, integrative review, from 2001 to 2017, in the databases MEDLINE, LILACS, Google Scholar and the Virtual Library SciELO, with consultation with experts via ResearchGate. Results: 21 studies developed by nurses in six countries were presented, showing the validity and reliability of the ASF-E instrument, assessing the effectiveness of family functioning, especially in chronic or vulnerable conditions. Appropriate methodology and level of evidence IV were used. Conclusion: it is concluded that the Framework of Systemic Organization has been used as it is considered a valid tool to evaluate family health in different contexts of family nursing. Descriptors: Family Nursing; Family; Nursing; Self-Efficacy; Nursing Theory; Review.RESUMENObjetivo: producir una encuesta de estudios sobre la aplicación del modelo teórico de la organización sistémica para evaluar la efectividad del funcionamiento familiar y construir el estado del arte. Método: este es un estudio bibliográfico descriptivo, tipo revisión integradora, de 2001 a 2017, en las bases de datos MEDLINE, LILACS, Google Scholar y SciELO Virtual Library, con consulta con expertos a través de ResearchGate. Resultados: se presentaron 21 estudios desarrollados por enfermeros en seis países, que muestran la validez y confiabilidad del instrumento ASF-E, evaluando la efectividad del funcionamiento familiar, especialmente en condiciones crónicas o vulnerables. Se utilizó la metodología apropiada y el nivel de evidencia IV. Conclusión: se concluye que el modelo teórico de la organización sistémica se ha utilizado porque se considera una herramienta válida para evaluar la salud familiar en diferentes contextos de Enfermería familiar. Descriptores: Enfermería de Familia; Enfermería; Familia; Autoeficacia; Teoria de Enfermería; Revisión.

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Peran Reticulocyte Hemoglobin Content (Ret-He) dalam Mendeteksi Defisiensi Besi pada Anak

Sari Pediatri ◽

10.14238/sp20.5.2019.316-23 ◽

2019 ◽

Vol 20 (5) ◽

pp. 316

Author(s):

Ika Maya Sandy ◽

Murti Andriastuti

Keyword(s):

Iron Deficiency ◽

Binding Capacity ◽

Total Iron ◽

Google Scholar ◽

Iron Binding ◽

Total Iron Binding Capacity ◽

Hemoglobin Content ◽

Level Of Evidence ◽

Iron Binding Capacity ◽

Reticulocyte Hemoglobin Content

Latar belakang. Defiseinsi besi (DB) didefinisikan sebagai penurunan total kandungan besi dalam tubuh yang ditandai dengan turunnya kadar feritin atau saturasi transferin. Gangguan perkembangan neurokognitif yang timbul akibat DB bersifat permanen. Identifikasi adanya DB penting untuk memulai terapi besi untuk mencegah komplikasi jangka panjang.Tujuan. Mengetahui peran Ret-He dalam mendeteksi DB pada anak dibandingkan dengan pemeriksaan biomarker penanda status besi lain (feritin, saturasi transferin, kadar besi serum, dan total iron binding capacity (TIBC)).Metode. Penelusuran pustaka database elektronik, yaitu Pubmed, Cochrane, ProQuest dan Google scholar dengan kata kunci “iron deficiency”, “AND” “reticulocyte hemoglobin content”, “AND” “children”.Hasil. Penelusuran literatur diperoleh 4 artikel yang terpilih kemudian dilakukan telaah kritis. Studi oleh Mateos dkk, dengan level of evidence 1c, diperoleh nilai cut-off: ≤ 25 pg, memiliki sensitivitas tertinggi dibanding studi lainnya, yaitu 94% dan spesifisitas 80%, NDP 54%, NDN 97%. Studi lain menentukan nilai cut-off yang berbeda-beda sehingga mempengaruhi nilai sensitivitas, spesifisitas, nilai duga positif dan negatif.Kesimpulan. Berdasarkan penelitian ilmiah yang telah dipaparkan dapat disimpulkan bahwa Ret-He dapat digunakan sebagai parameter untuk mendeteksi DB pada anak.

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Editorial characteristics and quality of the articles published by Brazilian Nursing journals

Revista da Escola de Enfermagem da USP ◽

10.1590/s1980-220x2017030003367 ◽

2018 ◽

Vol 52 (0) ◽

Author(s):

Renata Perfeito Ribeiro ◽

Maria Helena Palucci Marziale

Keyword(s):

Open Access ◽

Scientific Evidence ◽

International Community ◽

Online Version ◽

Google Scholar ◽

Scientific Journals ◽

Level Of Evidence ◽

Editorial Boards ◽

Publication Standards

ABSTRACT Objective: To analyze the editorial characteristics and the level of evidence of articles published by Nursing journals in Brazil. Method: Documentary research on the websites of five Nursing journals and analysis of the articles published in 2016, based on their level of evidence. The form used was validated by experts. Results: Editorial boards with Brazilian and foreign researchers, normalization and international ethical recommendations on the publications, online version with open access, continuous publication system (20.0%), Portuguese and English, foreign authors (4.0% to 14.7%). The information provided to the authors is not clear (20.0%), articles with level of evidence 4 (86.7%). The international community had access to some of the papers published, and the highest rates were JCR/WOS 0.6984, SJR/Scopus 0.396, H/Scopus index 26 and Google Scholar 30. Conclusion: Scientific journals follow international publication standards. Most of the articles published do not provide strong scientific evidence, which has an impact on the use of the knowledge, on the citations received and on the effective advancement of the knowledge of the area.

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Is intraoperative neuromonitoring effective in hip and pelvis orthopedic and trauma surgery? A systematic review

Journal of Orthopaedics and Traumatology ◽

10.1186/s10195-021-00605-8 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Luigi Murena ◽

Giulia Colin ◽

Micol Dussi ◽

Gianluca Canton

Keyword(s):

Systematic Review ◽

Sciatic Nerve ◽

Case Reports ◽

Trauma Surgery ◽

Hip Surgery ◽

Google Scholar ◽

Level Of Evidence ◽

Nerve Monitoring ◽

Advantages And Disadvantages ◽

Intraoperative Nerve Monitoring

Abstract Introduction Sciatic nerve injury is an uncommon but potentially devastating complication in hip and pelvis surgery. Intraoperative nerve monitoring (IONM) was applied since the seventies in neurosurgery and spine surgery. Nowadays, IONM has gained popularity in other surgical specialities including orthopaedic and trauma surgery. Aim of this systematic review is to resume the literature evidences about the effectiveness of intraoperative monitoring of sciatic nerve during pelvic and hip surgery. Methods Two reviewers (GC and MD) independently identified studies by a systematic search of PubMed and Google Scholar from inception of database to 10 January 2021. Inclusion criteria were: (a) English written papers, (b) use of any type of intraoperative nerve monitoring during traumatic or elective pelvic and hip surgery, (c) comparison of the outcomes between patients who underwent nerve monitoring and patient who underwent standard procedures, (d) all study types including case reports. The present review was conducted in accordance with the 2009 PRISMA statement. Results The literature search produced 224 papers from PubMed and 594 from Google Scholar, with a total amount of 818 papers. The two reviewer excluded 683 papers by title or duplicates. Of the 135 remaining, 72 were excluded after reading the abstract, and 31 by reading the full text. Thus, 32 papers were finally included in the review. Conclusions The use of IONM during hip and pelvis surgery is debated. The review results are insufficient to support the routine use of IONM in hip and pelvis surgery. The different IONM techniques have peculiar advantages and disadvantages and differences in sensitivity and specificity without clear evidence of superiority for any. Results from different studies and different interventions are often in contrast. However, there is general agreement in recognizing a role for IONM to define the critical maneuvers, positions or pathologies that could lead to sciatic nerve intraoperative damage. Level of evidence Level 2.

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