Characterization of urinary symptoms and children’s quality of life with ureteral stents based on the validation studies of the new questionnaire (USSQ)

2017 ◽  
Vol 16 (3) ◽  
pp. e1282
Author(s):  
R. Benrabah ◽  
M. Azli ◽  
S. Boumelit ◽  
M.B. Souid ◽  
M. Lounici
Keyword(s):  
Quality Of Life ◽  
Validation Studies ◽  
Urinary Symptoms ◽  
Ureteral Stents

scholarly journals Bone Pain in Multiple Myeloma (BPMM)—A Protocol for a Prospective, Longitudinal, Observational Study

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1596
Author(s):  
Marta Diaz-delCastillo ◽  
Rebecca E. Andrews ◽  
Aritri Mandal ◽  
Thomas L. Andersen ◽  
Andrew D. Chantry ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Myeloma ◽  
Observational Study ◽  
Bone Turnover ◽  
Bone Pain ◽  
Subjective Experience ◽  
Prospective Longitudinal ◽  
Bone Turnover Biomarkers

Multiple myeloma (MM) is a bone marrow neoplasia that causes bone pain in 70% patients. While preclinical models of MM have suggested that both nerve sprouting and nerve injury may be causative for the pain, there is a lack of clinical data. Thus, the primary aims of this clinical study are: (1) to provide a deep characterization of the subjective experience of pain and quality of life in MM patients; (2) to investigate disturbances in the bone innervation of MM patients. Secondary aims include exploring correlations between pain and serum inflammatory and bone turnover biomarkers. In a prospective, observational study (clinicaltrials.gov: NCT04273425), patients with suspected MM requiring a diagnostic iliac crest biopsy at Sheffield Teaching Hospital (UK) are invited to participate. Consenting patients answer seven standardized questionnaires assessing pain, quality of life and catastrophizing. Bone turnover biomarkers and inflammatory cytokines are measured in fasting serum samples, and bone innervation is evaluated in diagnostic biopsies. MM patients are invited to a follow-up upon completion of first line treatment. This will be the first deep characterization of pain in MM patients and its correlation with disturbances in bone innervation. Understanding how bone turnover and inflammation correlate to pain in MM is crucial to identify novel analgesic targets for this condition.

Second Prize (Co-winner): Indwelling Ureteral Stents: Evaluation of Quality of Life to Aid Outcome Analysis

2001 ◽  
Vol 15 (2) ◽  
pp. 151-154 ◽  
Author(s):  
H.B. Joshi ◽  
A. Stainthorpe ◽  
F.X. Keeley ◽  
R. MacDonagh ◽  
A.G. Timoney
Keyword(s):  
Quality Of Life ◽  
Outcome Analysis ◽  
Ureteral Stents

Discriminative power of the Sarcopenia Quality of Life (SarQoL®) questionnaire with the EWGSOP2 criteria

2020 ◽  
pp. 1-2
Author(s):  
A. Geerinck ◽  
M. Locquet ◽  
J.-Y. Reginster
Keyword(s):  
Quality Of Life ◽  
Grip Strength ◽  
Validation Studies ◽  
Discriminative Power ◽  
Validity And Reliability ◽  
Specific Instrument ◽  
Multiple Languages

The Sarcopenia Quality of Life (SarQoL®) questionnaire was developed in 2015 to fill the need for a specific instrument to measure quality of life in sarcopenia. Since then, its validity and reliability have been evaluated in multiple languages, and it is now available in 30 language-specific versions. In multiple validation studies, the SarQoL® has demonstrated its ability to discriminate between sarcopenic and non-sarcopenic subjects when diagnosed according to the EWGSOP criteria (1). However, these criteria have now been updated, and the discriminative power of the SarQoL® questionnaire should be reaffirmed using the EWGSOP2 criteria (2). The analysis presented below aims to establish whether the SarQoL® questionnaire can discriminate between sarcopenic, probably sarcopenic (low grip strength in the EWGSOP2 algorithm) and non-sarcopenic participants.

scholarly journals Unexpected benefits and potential therapeutic opportunities of tension free vaginal tape for stress urinary incontinence

2013 ◽  
Vol 27 (1) ◽  
pp. 6 ◽  
Author(s):  
Chendrimada Madhu ◽  
Penelope Harber ◽  
David Holmes
Keyword(s):  
Quality Of Life ◽  
Urinary Incontinence ◽  
Pelvic Floor ◽  
Stress Incontinence ◽  
Urinary Symptoms ◽  
Pelvic Floor Function ◽  
Vaginal Symptoms ◽  
Tension Free ◽  
Floor Function

Urinary incontinence is a debilitating problem in women with significant effects on quality of life. The tension free vaginal tape (TVT) improves urinary symptoms and achieves a high rate of patient satisfaction. The aim of the study was to evaluate the effect of TVT on vaginal symptoms, pelvic floor function and in turn quality of life. We hypothesize that the TVT is associated with an improvement in pelvic floor function. A prospective questionnaire- based analysis was conducted over a period of ten months in patients undergoing the TVT procedure. The International Consul - tation on Incontinence Modular Questionnaire - Vaginal Symptoms questionnaire was used to evaluate the vaginal symptoms pre-operatively and 6 months post-operatively. The results were compared to assess for any significant differences. A total of 31 patients were recruited for the study. There was a statistically significant improvement in vaginal symptoms score at 6 months in women undergoing TVT along with an improvement in urinary symptoms. This study suggests a positive impact of TVT insertion on vaginal symptomatology, which is an exciting prospect influencing patient counseling for treatment options of urinary stress incontinence. This finding may have an impact on performing concomitant surgeries for stress incontinence and pelvic organ prolapse. There is a need for further large–scale research to explore this aspect of unexpected benefit from the TVT.

scholarly journals Quality of life and vaginal symptoms of postmenopausal women using pessary for pelvic organ prolapse: a prospective study

2018 ◽  
Vol 64 (12) ◽  
pp. 1103-1107 ◽  
Author(s):  
Suelene C. Albuquerque Coelho ◽  
Marcos Marangoni-Junior ◽  
Luiz Gustavo Oliveira Brito ◽  
Edilson Benedito de Castro ◽  
Cássia Raquel Teatin Juliato
Keyword(s):  
Quality Of Life ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Urinary Symptoms ◽  
Pelvic Surgery ◽  
Subjective Impression ◽  
Vaginal Symptoms ◽  
Sf 36 ◽  
A Prospective Study

SUMMARY OBJECTIVE: The use of pessary is an option for the conservative treatment of pelvic organ prolapse (POP). However, here are few studies assess the quality of life (QoL) after inserting the pessary for POP. We have hypothesized that the use of pessary would modify QoL in women with POP. METHODS: A prospective, observational study was performed that included 19 women with advanced POP. Pessary was introduced, and the SF-36 (general quality of life) and ICIQ-VS (vaginal symptoms and quality of life subdomain) questionnaires were applied before the introduction and after six months. A single question about the satisfaction regarding the use of the device was presented (subjective impression). RESULTS: The mean age of the women included was 76 years. Most of them were non-caucasian (52.6%), with no prior pelvic surgery (57.5%), with urinary symptoms (78.9%). A third of the patients reported sexual activity. After treatment, 22.2% of them presented vaginal infection, and 27.7% increased vaginal discharge. Urinary symptoms remained unaltered. Women reported 100% satisfaction after using the pessary (77.7% partial improvement; 22.3% total improvement). SF-36 had significant improvement in three specific domains: general state of health (p=0.090), vitality (p=0.0497) and social aspects (p=0.007). ICIQ-VS presented a reduction in the vaginal symptoms (p < 0.0001) and an improvement in QoL (P < 0.0001). CONCLUSION: The use of pessary for six months improved the QoL and reduced vaginal symptoms for women with advanced POP.

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