scholarly journals S1868 Langerhans Cell Histiocytosis Mimicking Inflammatory Bowel Disease: A Rare Presentation of Multiorgan Myeloid Neoplasm in a Geriatric Patient

2021 ◽  
Vol 116 (1) ◽  
pp. S822-S822
Author(s):  
Mindy Ward ◽  
Precious Idogun ◽  
Nathan Seepaulsing ◽  
Richard Brown ◽  
Coppola Domenico ◽  
...  
2020 ◽  
Vol 26 (8) ◽  
pp. e85-e86
Author(s):  
Jerome Razanamahery ◽  
Sebastien Humbert ◽  
Delphine Weil-Verhoeven ◽  
Jean-Francois Emile ◽  
Lucine Vuitton ◽  
...  

Langerhans cell histiocytosis is a rare histiocytic disorder characterized by histology (CD68+, CD1a+ histiocytes). Presentation is heterogenous but gastrointestinal tract involvement is rare; although it can mimic inflammatory bowel disease, such an association is unusual.


2020 ◽  
Vol 7 (1) ◽  
pp. e000526
Author(s):  
Elmer Hoekstra ◽  
Rudolf Keunen ◽  
Michael van der Voorn

A wide variety of extraintestinal manifestations of inflammatory bowel disease (IBD) have been described, with joint or dermatological complaints as most prevalent. However, also neurological manifestations can occur, which are rarely recognised and therefore under-reported. We present an very unusual case of a young man who presented with the inability to walk, as a first presentations of IBD.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
L Armstrong ◽  
J Lockhart ◽  
H Mathers

Abstract Introduction Mondor's Disease (MD) is a rare condition characterised by thrombophlebitis of the superficial veins of the breast and anterior chest wall. Cases associated with inflammatory bowel disease are rare. Case A 54-year-old male presented to the symptomatic breast clinic with a 6-week history of a painful linear area on the anterolateral aspect of his left chest wall. There was no history of trauma or underlying coagulopathy. He also described increased stool frequency and crampy abdominal pain. On clinical examination, superficial thrombophlebitis with cording was noted along the outer upper quadrant of the chest wall. His past medical history included a previous diagnosis of ulcerative colitis, with no pharmacological treatment. He was subsequently referred to a gastroenterologist and all symptoms resolved following management of his underlying colitis. Discussion This gentleman’s thrombophlebitis followed the course of the thoracoepigastric vein. The occurrence of thromboembolic events has been documented in association with an exacerbation of ulcerative colitis; however, literature describing MD is scarce. The underlying aetiology is reportedly due to the hypercoagulable state identified in ulcerative colitis. There is a lack of consensus on the treatment of MD, however cases have responded well to the management of the precipitating colitis. Low molecular weight heparin can be used if chronicity ensues. Surgical management is not recommended. Conclusions MD is a rare presentation of ulcerative colitis. Clinicians should be aware of underlying aetiologies and a potential hypercoagulable state. Such cases in relation to UC require early diagnosis and treatment of underlying colitis.


2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Khin San Aye ◽  
Lin Lin Htun ◽  
Thet Mar Win ◽  
Mya Thida Aye ◽  
Drmyothettin Tin ◽  
...  

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, traditionally regarded as being limited to the colorectum. Although several gastroduodenal lesions have been reported in cases of UC, in general, duodenal lesions in UC are believed to be uncommon and gastric lesions in UC are a rare presentation. In this report, we presented a 66-year-old lady with upper GI presentation with gastroduodenal ulcerative colitis accompanying pancolonic UC.


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