scholarly journals The short- and long-term adverse effects of FGF-2 on tympanic membrane perforations

2018 ◽  
Vol 38 (3) ◽  
pp. 264-272
Author(s):  
L. ZHENG-CAI ◽  
L. ZI-HAN
Keyword(s):  
Adverse Effects ◽  
Tympanic Membrane ◽  
Tympanic Membrane Perforations ◽  
Short And Long Term ◽  
Long Term Adverse Effects

scholarly journals Postoperative Delirium

2021 ◽  
Vol 16 (SP1) ◽  
pp. 37-42
Author(s):  
Camilla L. Wong ◽  
Maia Von Maltzahn
Keyword(s):  
Risk Assessment ◽  
Adverse Effects ◽  
Postoperative Delirium ◽  
Interdisciplinary Team ◽  
Evidence Based ◽  
Évaluation Gériatrique ◽  
Prevention Interventions ◽  
Short And Long Term ◽  
Long Term Adverse Effects

There is strong evidence to support prevention of postoperative delirium through comprehensive geriatric assessment and multicomponent nonpharmacologic interventions. Risk assessment must be accompanied by communication of the risk to the patient, caregivers, and perioperative interdisciplinary team to engage all in evidence-based prevention interventions. However, once postoperative delirium has developed, efforts should be focused on prevention of short- and long-term adverse effects.   RÉSUMÉDes données probantes solides appuient la prévention du délire postopératoire en recourant à une évaluation gériatrique complète et à des interventions non pharmacologiques à plusieurs composantes. L’évaluation des risques doit s’accompagner d’une communication du risque au patient, aux soignants et à l’équipe interdisciplinaire périopératoire afin que tous participent aux interventions de prévention fondées sur des données probantes. Toutefois, une fois que le délire postopératoire s’est installé, les efforts doivent être axés sur la prévention des effets indésirables à court et à long terme.

Useful versus Harmful Prison Policies

2017 ◽  
Author(s):  
John Wooldredge
Keyword(s):  
General Population ◽  
Adverse Effects ◽  
Best Practices ◽  
Empirical Research ◽  
The Other ◽  
Common Source ◽  
Short And Long Term ◽  
Cumulative Knowledge ◽  
Long Term Adverse Effects

This chapter provides a synthesis of some of the useful prison policies discussed throughout this volume. The sources of useful versus harmful policies in addition to the implications of the latter are discussed. Perhaps the most common source of harmful policies has been heavier emphases placed on punishment by politicians and court actors who are further removed from the prison experience. Common denominators of policies that have generally improved the welfare of prisoners and/or prison staff, on the other hand, include grounding in an increasingly humanitarian view of offenders, a growing awareness of both short- and long-term adverse effects of incarceration on offenders and the general population, greater reliance on empirically based strategies, and interagency collaborations to ensure long-term solutions while minimizing unanticipated ill effects. The greatest obstacles to overcoming harmful policies are also reviewed, highlighting the importance of cumulative knowledge and ongoing empirical research on best practices.

Oil pollution and fisheries

1982 ◽  
Vol 297 (1087) ◽  
pp. 401-411 ◽  
Keyword(s):  
Water Quality ◽  
Adverse Effects ◽  
Oil Pollution ◽  
Coastal Areas ◽  
Short Term ◽  
Fish Stocks ◽  
Local Impacts ◽  
Reduced Water ◽  
Long Term Adverse Effects

The term ‘pollution’ is taken in its broadest sense and effects are recognized to be due to interference, tainting and toxicity. Each of these types of impact is discussed and assessed. It is concluded that no long-term adverse effects on fish stocks can be attributed to oil but that local impacts can be extremely damaging in the short term and that produce from specific localities can be tainted and unmarketable for long periods. In some coastal areas oil can be one among several contributors to reduced water quality, and the implications of this are discussed.

scholarly journals Long-Term Consequences of Adolescent Exposure to THC-Rich/CBD-Poor and CBD-Rich/THC-Poor Combinations: A Comparison with Pure THC Treatment in Female Rats

2021 ◽  
Vol 22 (16) ◽  
pp. 8899
Author(s):  
Marina Gabaglio ◽  
Erica Zamberletti ◽  
Cristina Manenti ◽  
Daniela Parolaro ◽  
Tiziana Rubino
Keyword(s):  
Adverse Effects ◽  
Chronic Administration ◽  
Female Rats ◽  
Acid Decarboxylase ◽  
Long Term Effects ◽  
Gabaergic Neurotransmission ◽  
Long Term Consequences ◽  
Adolescent Exposure ◽  
Long Term Adverse Effects

Cannabis is the most-used recreational drug worldwide, with a high prevalence of use among adolescents. In animal models, long-term adverse effects were reported following chronic adolescent exposure to the main psychotomimetic component of the plant, delta-9-tetrahydrocannabinol (THC). However, these studies investigated the effects of pure THC, without taking into account other cannabinoids present in the cannabis plant. Interestingly, cannabidiol (CBD) content seems to mitigate some of the side effects of THC, at least in adult animals. Thus, in female rats, we evaluated the long-term consequences of a co-administration of THC and CBD at a 3:1 ratio, chosen based on the analysis of recently confiscated illegal cannabis samples in Europe. CBD content is able to mitigate some of the long-term behavioral alterations induced by adolescent THC exposure as well as long-term changes in CB1 receptor and microglia activation in the prefrontal cortex (PFC). We also investigated, for the first time, possible long-term effects of chronic administration of a THC/CBD combination reminiscent of “light cannabis” (CBD:THC in a 33:1 ratio; total THC 0.3%). Repeated administration of this CBD:THC combination has long-term adverse effects on cognition and leads to anhedonia. Concomitantly, it boosts Glutamic Acid Decarboxylase-67 (GAD67) levels in the PFC, suggesting a possible lasting effect on GABAergic neurotransmission.

Minimising the Long-Term Adverse Effects of Childhood Leukaemia Therapy

Drug Safety ◽  
2002 ◽  
Vol 25 (15) ◽  
pp. 1057-1077 ◽  
Author(s):  
Claudia Langebrake ◽  
Dirk Reinhardt ◽  
J??rg Ritter
Keyword(s):  
Adverse Effects ◽  
Childhood Leukaemia ◽  
Leukaemia Therapy ◽  
Long Term Adverse Effects

Nanofibrous-spherical cage mimicking a ball of pearl-necklaces for super capture of heavy metal ions

2021 ◽  
Author(s):  
Youngkyun Jung ◽  
Ung Su Choi ◽  
Young Gun Ko
Keyword(s):  
Heavy Metal ◽  
Adverse Effects ◽  
Metal Ions ◽  
Heavy Metal Ions ◽  
High Performance ◽  
Poor Response ◽  
Separation Technology ◽  
Long Term Adverse Effects

The late and poor response in the initial stages of big heavy metal leakage accidents cause long-term adverse effects on nature and humans. Fast and high-performance separation technology with low...

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