scholarly journals Spectral analyses of fresh and dry Hypericum perforatum L. Effects with colloidal nano silver 30 ppm

2022 ◽  
Vol 9 (1) ◽  
pp. 41-47
Author(s):  
Ignat Ignatov ◽  
Teodora Petrova Popova ◽  
Ralitsa Bankova ◽  
Nikolai Neshev

Spectral analyses of 1% water extracts of fresh and dry Hypericum perforatum L. and 1% dry H. perforatum with colloidal nano silver (NSPs) 30 ppm were conducted. The nano silver is standardised and patented by the Swiss company Evodrop. Non-equliblrium energy spectrum (NES) and Differential non-equliblrium energy spectrum (DNES) methods were used for the spectral analysis. A comparative analysis of 1% extracts of fresh and dry H. perforatum was performed in order to determine the local extremums for effects of nerve tissue conductivity at (-0.1112) eV, anti-inflammatory (-0.1212) eV, anti-tumor effects (-0.1387) eV. The results showed stimulating effect on the nervous system and improvement of nerve conduction (local extremums E=-0.1112 eV)(?=11.15 ?m) (?=897 cm-1), as well as anti-inflammatory effect (E = -0.1212 eV)( ?=10.23 ?m) (?=978 cm-1) and inhibition of development of tumor cells at a molecular level (E=-0.1387 eV) (?=8.95 ?m) (?=1117 cm-1). It was found that clusters of 16 and 15 water molecules are formed in the water herbal extracts of fresh H. perforatum and of dry H. perforatum with AgNPs 30 ppm. The fresh plant showed better results then the dry one. The addition of colloidal nano silver 30 ppm led to better results of the drug.

1988 ◽  
Vol 77 (01) ◽  
pp. 27-29 ◽  
Author(s):  
S. Kumar ◽  
D.R. Lohar ◽  
D. Chaturvedi ◽  
G.D. Gaur ◽  
P.N. Varma

AbstractArthritis was produced in adult albino rats weighing 120±10 g through intramuscular injections of 0.5 ml of 2% w/w formalin beneath the plantar aponeurosis on the first and third day. The anterioposterior diameter of the ankle was recorded and statistically analyzed. It was evident that relatively low doses, 0.25 ml/100 g body weight, of tincture of Hypericum perforatum produced a significant 48% anti-inflammatory effect, whereas higher doses, 0.5 ml/100 g body weight, of the drug showed 32% activity under identical conditions. Parallel studies with 1 mg/100 g body weight hydrocortisone administration gave similar anti-inflammatory effects.Local application of an alcoholic extract of the drug in very small doses also produced significant skin softness and flexibility of muscle.


Author(s):  
Samira Salem ◽  
Essaid Leghouchi ◽  
Rachid Soulimani ◽  
Jaouad Bouayed

Abstract. Paw edema volume reduction is a useful marker in determining the anti-inflammatory effect of drugs and plant extracts in carrageenan-induced acute inflammation. In this study, the anti-inflammatory effect of Lobaria pulmonaria (LP) and Parmelia caperata (PC), two lichen species, was examined in carrageenan-induced mouse paw edema test. Compared to the controls in carrageenan-induced inflammation (n = 5/group), our results showed that pretreatment by single oral doses with PC extract (50–500 mg/kg) gives better results than LP extract (50–500 mg/kg) in terms of anti-edematous activity, as after 4 h of carrageenan subplantar injection, paw edema formation was inhibited at 82–99% by PC while at 35–49% by LP. The higher anti-inflammatory effect of PC, at all doses, was also observed on the time-course of carrageenan-induced paw edema, displaying profile closely similar to that obtained with diclofenac (25 mg/kg), an anti-inflammatory drug reference (all p < 0.001). Both LP and PC, at all doses, significantly ameliorated liver catalase (CAT) activity (all p < 0.05). However, superoxide dismutase (SOD) activity, glutathione peroxidase (GPx) activity and glutathione (GSH) levels were found increased in liver of PC- compared to LP-carrageenan-injected mice. Our findings demonstrated on one hand higher preventive effects of PC compared to LP in a mouse carrageenan-induced inflammatory model and suggested, on the other hand, that anti-inflammatory effects elicited by the two lichens were closely associated with the amelioration in the endogenous antioxidant status of liver.


Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
AH Mollik ◽  
W Mozammel Haq ◽  
S Chandra Bachar ◽  
R Jahan ◽  
M Rahmatullah

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
WM Shaik Mossadeq ◽  
K Syamimi ◽  
MP Azyyati ◽  
ZA Zakaria ◽  
AK Arifah ◽  
...  

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
E Sofic ◽  
A Copra Janicijevic ◽  
M Maksimovic ◽  
I Tahirovic ◽  
L Klepo ◽  
...  

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
IST Figueiredo ◽  
FT Benevides ◽  
NMS Queiroz ◽  
LM Marques ◽  
TFG Souza ◽  
...  

Phlebologie ◽  
2008 ◽  
Vol 37 (05) ◽  
pp. 259-265 ◽  
Author(s):  
H. Kutzner ◽  
G. Hesse

SummaryThe reason of the so called ulcerated capillaritis alba or idiopathic atrophie blanche is vasculopathy caused by severe venous hypertension. Thrombosed and rarificated vessels worsen the oxygenation, increase permanent inflammation and impede the necessary compression therapy. The anti-inflammatory effects of heparin alleviate pain and being independent from the antithrombotic ones it needs much lower doses for treatment. This anti-inflammatory effect is now becoming more important in clinical phlebology. Case studies of more than 50 patients and one prospective randomized study of 87 patients clearly demonstrate the ameliorated healing of ulcerated atrophie blanche. In our office we could document this positive effect with 22 patients. We present the pathophysiology of low molecular heparins for ulcerated capillaritis alba and our own experiences with it.


Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
G Zdunić ◽  
D Goðevac ◽  
M Milenković ◽  
K Šavikin ◽  
S Petrović

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