scholarly journals THE STATE OF THE SIRS AND ENDOTHELIAL FUNCTION IN HYPERTENSIVE PATIENTS, STAGE II IN THE PROCESS OF ISCHEMIC HEART DISEASE DEVELOPING

2015 ◽  
Vol 0 (4) ◽  
Author(s):  
I. M. Fushtey ◽  
V. A. Mochonyi ◽  
E. V. Sid’ ◽  
N. F. Efimenko
Keyword(s):  
Heart Disease ◽  
Endothelial Function ◽  
Ischemic Heart Disease ◽  
The State ◽  
Ischemic Heart ◽  
Stage Ii ◽  
Hypertensive Patients

scholarly journals Gender Differences in the Risk of Ischemic Heart Disease According to Healthcare Utilization and Medication Adherence among Newly Treated Korean Hypertensive Patients

2021 ◽  
Vol 18 (3) ◽  
pp. 1274
Author(s):  
Jiae Shin ◽  
Dongwoo Ham ◽  
Hee Young Paik ◽  
Sangah Shin ◽  
Hyojee Joung
Keyword(s):  
Gender Differences ◽  
Heart Disease ◽  
Medication Adherence ◽  
Ischemic Heart Disease ◽  
Healthcare Utilization ◽  
Healthcare Providers ◽  
Ischemic Heart ◽  
Health Examination ◽  
Men And Women ◽  
Hypertensive Patients

We aimed to investigate gender differences in ischemic heart disease (IHD) according to healthcare utilization and medication adherence among newly treated Korean hypertensive adults. The National Sample Cohort version 2.0 of the National Health Insurance Service was used for analysis. Newly treated hypertensive patients ≥ 20 years and without IHD in 2002 were selected from a population that underwent health examination during 2003–2006. Of those patients, 11,942 men and 11,193 women were analyzed and followed up for 10 years. We determined the association between IHD and healthcare utilization and medication adherence using the Cox proportional hazards model. Hypertensive women patients had a lower risk of IHD than men patients (hazard ratio [HR] = 0.93, 95% confidence interval [CI] 0.88–1.00). The IHD risk was increased in patients who visited healthcare providers > 12 times/person-year (HR = 2.97, 95% CI 2.79–3.17), paid high out-of-pocket expense/person-year (HR = 1.55, 95% CI 1.41–1.69), and had medication nonadherence (HR = 1.67, 95% CI 1.58–1.77). However, the risk was decreased in patients who used both urban and rural areas (HR 0.75, 95% CI 0.67–0.84) and mixed types of providers (HR = 0.93, CI 0.88–0.99). The risk of IHD was significantly different between men and women only in the visiting frequency to healthcare providers (men, HR = 3.21, 95% CI 2.93–3.52; women, HR = 2.78, 95% CI 2.53–3.04, p for interaction = 0.0188). In summary, the risk of IHD was similar according to healthcare utilization and medication adherence between men and women, except visiting frequency to healthcare providers.

scholarly journals Dynamics of endothelian function in different treatment strategies in stable ischemic heart disease

2019 ◽  
Vol 11 (1) ◽  
pp. 5-12
Author(s):  
Sergey A. Sayganov ◽  
Anastasiia M. Kuzmina-Krutetskaia
Keyword(s):  
Endothelial Cells ◽  
Heart Disease ◽  
Endothelial Dysfunction ◽  
Endothelial Function ◽  
Ischemic Heart Disease ◽  
Peripheral Blood ◽  
Ischemic Heart ◽  
Circulating Endothelial Cells ◽  
Lipid Lowering ◽  
Stable Ischemic Heart Disease

Aim. To assess the dynamics of endothelial function by determining circulating endothelial cells in peripheral blood in patients with stable ischemic heart disease within various treatment approaches. Material and methods. The study involved 98 patients with stable ischemic heart disease and 30 patients in the control group without coronary atherosclerosis. Endothelial function was assessed by determining the number of circulating endothelial cells in peripheral blood using flow cytofluorimetry with antibodies to cell surface markers: CD146+CD45– at the baseline. Depending on the treatment tactics, the study participants were divided into 3 groups: the medicamental therapy group, the group of coronary stenting, and the group of coronary bypass surgery. After 3 months from the baseline, dinamics assessment of endothelial dysfunction was performed. Results. Endothelial dysfunction was observed in all patients with obstructive lesions of the coronary blood flow and associated with effort angina class and anatomical severity of coronary disease. Improvement of endothelial function was facilitated by lipid-lowering therapy. Revascularization by coronary stenting impaired endothelial function in three months after the intervention. Mycoardial revascularization by coronary bypass did not impair endothelial function. Conclusion. Examination of endothelial dysfunction by determining the number of circulating endothelial cells in peripheral blood can be used to assess the severity of endothelial dysfunction in patients with IHD receiving lipid-lowering therapy and undergoing surgical revascularization.

Hypertonic disease and its involvement in the class of diseases of the circulatory system: epidemiological situation in Ukraine

2020 ◽  
Vol 26 (2-3) ◽  
pp. 68-74
Author(s):  
V.V. Ruden' ◽  
◽  
V.I. Diachyschyn ◽  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cerebrovascular Disease ◽  
Negative Impact ◽  
Circulatory System ◽  
Well Being ◽  
The State ◽  
Ischemic Heart ◽  
Steady Increase ◽  
Circulatory System Diseases

Aim. A substantiation by the types of morbidity of biostatistic tendencies in the development of hypertonic disease and its involvement in the existing pathologies of the class of diseases of the circulatory system among the population of Ukraine. Material and Methods. An epidemiological, cross-sectional, continuous, prospective study was conducted with the use of statistical data of the Health Statistics Center of the Ministry of Health of Ukraine and the State Statistics Service of Ukraine (1993 and 2017), summarizing and processing them in spreadsheets of Microsoft Office Excel 2016 using retrospective, biostatistical and abstract research methods, as well as methods of copying, deductive awareness, structural-logical analysis and systematic principles. Results and Discussion. The results clearly indicated a steady increase in all forms of hypertonic disease among the population of Ukraine over the studied time period by Рincr=119.8%, when in 2017 this pathology affected ngen=10,388,376 persons, with the prevalence indicator Рgen= 29,844.1о/оооо, which testified that every fourth citizen had a case of hypertonic disease, whereas hypertonic disease accompanied ischemic heart disease in Рpr=40.4% of cases, - cerebrovascular disease in Рpr=23.1% of cases and - strokes in Рpr= 35.8% of cases. Conclusions. It is established that hypertonic disease is one of the most prevalent diseases of the cardiovascular system and has a direct negative impact on of socio-economic well-being and resource provision for society and, based on achievements in etiopathology, diagnostics and treatment, requires the highest governmental structures of the state to undertake prompt and adequate managerial preventive actions aimed at strengthening the health of patients with hypertonic disease and of changing the lifestyle of the population in consideration of established risk factors in the occurrence of this pathology. Keywords: circulatory system diseases, hypertonic disease, general and primary morbidity, tendencies, involvement, ischemic heart disease, cerebrovascular disease, stroke

Sign in / Sign up

Export Citation Format

Share Document