scholarly journals Microglial adipobiology: a new concept for understanding the adipose tissue-brain crosstalk in health and disease

Adipobiology ◽  
2019 ◽  
Vol 10 (0) ◽  
pp. 25
Author(s):  
Marin Zhelezov
Keyword(s):  
Adipose Tissue ◽  
Health And Disease

scholarly journals Role of Epicardial Adipose Tissue in Health and Disease: A Matter of Fat?

2017 ◽  
pp. 1051-1082 ◽  
Author(s):  
Bénédicte Gaborit ◽  
Coralie Sengenes ◽  
Patricia Ancel ◽  
Alexis Jacquier ◽  
Anne Dutour
Keyword(s):  
Adipose Tissue ◽  
Epicardial Adipose Tissue ◽  
Health And Disease

scholarly journals Adipose Tissue in Health and Disease

Obesity ◽  
2020 ◽  
Author(s):  
Fernanda-Isadora Corona-Meraz ◽  
Jesus-Aureliano Robles-De Anda ◽  
Perla-Monserrat Madrigal-Ruiz ◽  
Gustavo-Ignacio Díaz-Rubio ◽  
Jorge Castro-Albarrán ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Health And Disease

Role of Perivascular Adipose Tissue in Health and Disease

2017 ◽  
pp. 23-59 ◽  
Author(s):  
Maria S. Fernández-Alfonso ◽  
Beatriz Somoza ◽  
Dmitry Tsvetkov ◽  
Artur Kuczmanski ◽  
Mick Dashwood ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Perivascular Adipose Tissue ◽  
Health And Disease

scholarly journals Adipose tissue browning in cardiometabolic health and disease

2019 ◽  
Vol 60 (5) ◽  
pp. 294-295 ◽  
Author(s):  
Alexios S. Antonopoulos ◽  
Dimitris Tousoulis
Keyword(s):  
Adipose Tissue ◽  
Cardiometabolic Health ◽  
Health And Disease ◽  
Tissue Browning

Adipokines and the cardiovascular system: mechanisms mediating health and disease

2012 ◽  
Vol 90 (8) ◽  
pp. 1029-1059 ◽  
Author(s):  
Josette M. Northcott ◽  
Azadeh Yeganeh ◽  
Carla G. Taylor ◽  
Peter Zahradka ◽  
Jeffrey T. Wigle
Keyword(s):  
Cardiovascular Disease ◽  
Adipose Tissue ◽  
Cardiovascular System ◽  
Cardiac Fibroblasts ◽  
Tissue Expansion ◽  
Cell Types ◽  
Vessel Growth ◽  
Major Cell Type ◽  
Health And Disease ◽  
Cardiovascular Cells

This review focuses on the role of adipokines in the maintenance of a healthy cardiovascular system, and the mechanisms by which these factors mediate the development of cardiovascular disease in obesity. Adipocytes are the major cell type comprising the adipose tissue. These cells secrete numerous factors, termed adipokines, into the blood, including adiponectin, leptin, resistin, chemerin, omentin, vaspin, and visfatin. Adipose tissue is a highly vascularised endocrine organ, and different adipose depots have distinct adipokine secretion profiles, which are altered with obesity. The ability of many adipokines to stimulate angiogenesis is crucial for adipose tissue expansion; however, excessive blood vessel growth is deleterious. As well, some adipokines induce inflammation, which promotes cardiovascular disease progression. We discuss how these 7 aforementioned adipokines act upon the various cardiovascular cell types (endothelial progenitor cells, endothelial cells, vascular smooth muscle cells, pericytes, cardiomyocytes, and cardiac fibroblasts), the direct effects of these actions, and their overall impact on the cardiovascular system. These were chosen, as these adipokines are secreted predominantly from adipocytes and have known effects on cardiovascular cells.

scholarly journals The role of sex steroids in white adipose tissue adipocyte function

Reproduction ◽  
2017 ◽  
Vol 153 (4) ◽  
pp. R133-R149 ◽  
Author(s):  
A E Newell-Fugate
Keyword(s):  
Adipose Tissue ◽  
Sexual Dimorphism ◽  
White Adipose Tissue ◽  
Hormonal Factors ◽  
Obesity Epidemic ◽  
Health And Disease ◽  
Males And Females ◽  
Hormonal Milieu ◽  
Gender Influences

With the increasing knowledge that gender influences normal physiology, much biomedical research has begun to focus on the differential effects of sex on tissue function. Sexual dimorphism in mammals is due to the combined effects of both genetic and hormonal factors. Hormonal factors are mutable particularly in females in whom the estrous cycle dominates the hormonal milieu. Given the severity of the obesity epidemic and the fact that there are differences in the obesity rates in men and women, the role of sex in white adipose tissue function is being recognized as increasingly important. Although sex differences in white adipose tissue distribution are well established, the mechanisms affecting differential function of adipocytes within white adipose tissue in males and females remain largely understudied and poorly understood. One of the largest differences in the endocrine environment in males and females is the concentration of circulating androgens and estrogens. This review examines the effects of androgens and estrogens on lipolysis/lipogenesis, adipocyte differentiation, insulin sensitivity and adipokine production in adipocytes from white adipose tissue with a specific emphasis on the sexual dimorphism of adipocyte function in white adipose tissue during both health and disease.

scholarly journals Fatty acid profiles in adipose tissues and liver differ between horses and ponies

2018 ◽  
Author(s):  
Stephanie Adolph ◽  
Carola Schedlbauer ◽  
Dominique Blaue ◽  
Axel Schöniger ◽  
Claudia Gittel ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Liver Tissue ◽  
Lipid Extraction ◽  
Lipid Classes ◽  
Adipose Tissues ◽  
Health And Disease

AbstractFatty acids, as key components of cellular membranes and complex lipids, may play a central role in endocrine signalling and the function of adipose tissue and liver. Thus, the lipid fatty acid composition may play a role in health and disease status in the equine. This study aimed to investigate the fatty acid composition of different tissues and liver lipid classes by comparing Warmblood horses and Shetland ponies under defined conditions. We hypothesized that ponies show different lipid patterns than horses in adipose tissue, liver and plasma. Six Warmblood horses and six Shetland ponies were housed and fed under identical conditions. Tissue and blood sampling were performed following a standardized protocol. A one-step lipid extraction, methylation and trans-esterification method with subsequent gas chromatography was used to analyse the total lipid content and fatty acid profile of retroperitoneal, mesocolon and subcutaneous adipose tissue, liver and plasma. In the adipose tissues, saturated fatty acids (SFAs) and n-9 monounsaturated fatty acids (n-9 MUFAs) were most present in ponies and horses. N-6 polyunsaturated fatty acids (n-6 PUFAs), followed by SFAs, were most frequently found in liver tissue and plasma in all animals. Horses, in comparison to ponies, had significantly higher n-6 PUFA levels in all tissues and plasma. In liver tissue, horses had significantly lower hepatic iso-branched-chain fatty acids (iso-BCFAs) than ponies. The hepatic fatty acid composition of selected lipid classes was different between horses and ponies. In the polar PL fraction, horses had low n-9 MUFA and n-3 PUFA contents but higher n-6 PUFA contents than ponies. Furthermore, iso-BCFAs are absent in several hepatic lipid fractions of horses but not ponies. The differences in fatty acid lipid classes between horses and ponies provide key information on the species- and location-specific regulation of FA metabolism, thus affecting health and disease risk.

Sign in / Sign up

Export Citation Format

Share Document