Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin

This study demonstrates the effect of a single high-intensity interval training (HIIT) session on the redox status of rat ovaries with excess adiposity. Forty Wistar female rats (mean (±s.e.m.) weight 94.40 ± 13.40 g) were divided into two groups and fed either a standard diet (SD) or a high-fat diet (HFD) for 62 days. At the end of this period, the rats were subjected to a single HIIT session and were killed 24 h after exercise. Both groups subjected to exercise (SDex and HFDex) generated a significantly higher antioxidant environment by presenting a higher thiol content, which represents a lower oxidation rate of GSH than their respective controls (SD and HFD). The percentage of morphologically normal primary follicles decreased, whereas that of antral follicles increased, in the SDex group. In addition, the HFD group had a higher percentage of degenerated antral follicles than the SD and SDex groups. Cells immunoreactive for α-smooth muscle actin were seen in the cortical stroma and thecal layer enclosing late secondary and tertiary follicles in all groups. Moreover, heme oxygenase and cytochrome P450 family 19 subfamily A member 1 (Cyp19A1) labelling was seen in all antral follicles. Progesterone concentrations were significantly higher in the HFDex than SDex group. In conclusion, this study indicates that a single session of HIIT may result in an improvement in ovary redox status because of metabolic muscle activity by inducing physiological adaptation after exercise in a paracrine manner.

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High-intensity interval training (HIIT) effectively enhances heart function via miR-195 dependent cardiomyopathy reduction in high-fat high-fructose diet-induced diabetic rats

Archives of Physiology and Biochemistry ◽

10.1080/13813455.2018.1511599 ◽

2018 ◽

Vol 126 (3) ◽

pp. 250-257 ◽

Cited By ~ 4

Author(s):

Soheyla Khakdan ◽

Maryam Delfan ◽

Maryam Heydarpour Meymeh ◽

Faranak Kazerouni ◽

Hamid Ghaedi ◽

...

Keyword(s):

High Intensity ◽

Heart Function ◽

Interval Training ◽

Diabetic Rats ◽

High Intensity Interval Training ◽

High Fat ◽

High Fructose Diet ◽

High Fructose ◽

High Intensity Interval

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Repeat sprint ability and the role of high-intensity interval training

Advanced Strength and Conditioning ◽

10.4324/9781315542348-6 ◽

2017 ◽

pp. 87-100

Author(s):

Anthony Turner ◽

David Bishop

Keyword(s):

High Intensity ◽

Interval Training ◽

High Intensity Interval Training ◽

High Intensity Interval ◽

Repeat Sprint Ability ◽

Repeat Sprint ◽

Sprint Ability

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The acute physiological and perceptual effects of recovery interval intensity during cycling-based high-intensity interval training

European Journal of Applied Physiology ◽

10.1007/s00421-020-04535-x ◽

2020 ◽

Author(s):

Christopher R. J. Fennell ◽

James G. Hopker

Keyword(s):

Oxygen Consumption ◽

High Intensity ◽

Lactate Threshold ◽

Interval Training ◽

Peak Oxygen Consumption ◽

High Intensity Interval Training ◽

Active Recovery ◽

Recovery Interval ◽

High Intensity Interval

Abstract Purpose The current study sought to investigate the role of recovery intensity on the physiological and perceptual responses during cycling-based aerobic high-intensity interval training. Methods Fourteen well-trained cyclists ($$\dot{V}{\text{O}}_{{{\text{2peak}}}}$$ V ˙ O 2peak : 62 ± 9 mL kg−1 min−1) completed seven laboratory visits. At visit 1, the participants’ peak oxygen consumption ($$\dot{V}{\text{O}}_{{{\text{2peak}}}}$$ V ˙ O 2peak ) and lactate thresholds were determined. At visits 2–7, participants completed either a 6 × 4 min or 3 × 8 min high-intensity interval training (HIIT) protocol with one of three recovery intensity prescriptions: passive (PA) recovery, active recovery at 80% of lactate threshold (80A) or active recovery at 110% of lactate threshold (110A). Results The time spent at > 80%, > 90% and > 95% of maximal minute power during the work intervals was significantly increased with PA recovery, when compared to both 80A and 110A, during both HIIT protocols (all P ≤ 0.001). However, recovery intensity had no effect on the time spent at > 90% $$\dot{V}{\text{O}}_{{{\text{2peak}}}}$$ V ˙ O 2peak (P = 0.11) or > 95% $$\dot{V}{\text{O}}_{{{\text{2peak}}}}$$ V ˙ O 2peak (P = 0.50) during the work intervals of both HIIT protocols. Session RPE was significantly higher following the 110A recovery, when compared to the PA and 80A recovery during both HIIT protocols (P < 0.001). Conclusion Passive recovery facilitates a higher work interval PO and similar internal stress for a lower sRPE when compared to active recovery and therefore may be the efficacious recovery intensity prescription.

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Aquatic High Intensity Interval Training for Cardiometabolic Health

American Journal of Lifestyle Medicine ◽

10.1177/1559827615583640 ◽

2016 ◽

Vol 11 (1) ◽

pp. 64-76 ◽

Cited By ~ 9

Author(s):

Elizabeth F. Nagle ◽

Mary E. Sanders ◽

Barry A. Franklin

Keyword(s):

High Intensity ◽

Interval Training ◽

Cardiometabolic Health ◽

Attractive Alternative ◽

High Intensity Interval Training ◽

Constant Intensity ◽

Acute Responses ◽

Fitness Benefits ◽

High Intensity Interval

High-intensity interval training (HIIT) has emerged as an attractive alternative to traditional continuous exercise training (CT) programs for clinical and healthy populations who find that they can achieve equal or greater fitness benefits in less time. Land-based HIIT may not be an appropriate choice for some participants. Few studies have explored the acute responses and chronic adaptations of HIIT in an aquatic environment, and no study has compared the cardiometabolic responses of an aquatic-based program to a land-based HIIT program. Shallow-water aquatic exercise (AE) programs utilizing HIIT have elicited comparable and, in some cases, greater physiological responses compared with constant-intensity or continuous AE regimens. Factors that may explain why HIIT routines evoke greater cardiometabolic responses than CT protocols may be based on the types of exercises and how they are cued to effectively manipulate hydrodynamic properties for greater intensities. Favorable aquatic HIIT protocols such as the S.W.E.A.T. system may serve as a beneficial alternative to land-based HIIT programs for clinical, and athletic populations, potentially reducing the likelihood of associated musculoskeletal and orthopedic complications. Hence, the purpose of this review is to examine the role of AE as an alternative safe and effective HIIT modality.

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Protein Composition of Circulating Extracellular Vesicles Immediately Changed by Particular Short Time of High-Intensity Interval Training Exercise

Frontiers in Physiology ◽

10.3389/fphys.2021.693007 ◽

2021 ◽

Vol 12 ◽

Author(s):

Yoshinao Kobayashi ◽

Akiko Eguchi ◽

Yasuyuki Tamai ◽

Sanae Fukuda ◽

Mina Tempaku ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Extracellular Vesicles ◽

Pulse Rate ◽

High Intensity ◽

Interval Training ◽

Metabolic Effects ◽

High Intensity Interval Training ◽

High Intensity Interval ◽

Short Time

Introduction/PurposeHigh-intensity interval training (HIIT) promotes various biological processes and metabolic effects in multiple organs, but the role of extracellular vesicles (EVs) released from a variety of cells is not fully understood during HIIT exercise (HIIT-Ex). We investigated the changes in circulating number and proteomic profile of EVs to assess the effect of HIIT-Ex.MethodsSeventeen young men (median age, 20 years) were enrolled in the study. Total duration of the HIIT-Ex was 4 min. Blood samples were collected from before HIIT-Ex (pre-HIIT-Ex), at the immediate conclusion of HIIT-Ex (T0), at 30 min (T30), and at 120 min after HIIT-Ex. The pulse rate and systolic blood pressure were measured. Circulating EVs were characterized, and EV proteins were detected via nano liquid chromatography tandem mass spectrometry.ResultsThe pulse rate and systolic blood pressure at T0 to pre-HIIT-Ex were significantly higher. Circulating EV number was significantly altered throughout the HIIT-Ex, and the source of circulating EVs included skeletal muscle, hepatocytes, and adipose tissue. Proteomic analysis identified a total of 558 proteins within isolated circulating EVs from pre-HIIT-Ex, T0, and T30. Twenty proteins in total were significantly changed at pre-HIIT-Ex, T0, and T30 and are involved in a variety of pathways, such as activation of coagulation cascades, cellular oxidant detoxification, and correction of acid–base imbalance. Catalase and peroxiredoxin II were increased at T0.ConclusionThe circulating EV composition can be immediately changed by particularly a short time of HIIT-Ex, indicating that EVs may intercommunicate across various organs rapidly in response to HIIT-Ex.

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