scholarly journals Effect of dietary salt intake on epithelial Na+ channels (ENaCs) in the hypothalamus of Dahl salt-sensitive rats

2018 ◽  
Vol 6 (16) ◽  
pp. e13838 ◽  
Author(s):  
Natalie J. Mills ◽  
Kaustubh Sharma ◽  
Katie Huang ◽  
Ryoichi Teruyama

2017 ◽  
Vol 595 (17) ◽  
pp. 5857-5874 ◽  
Author(s):  
Kaustubh Sharma ◽  
Masudul Haque ◽  
Richard Guidry ◽  
Yoichi Ueta ◽  
Ryoichi Teruyama


2020 ◽  
Vol 16 (5) ◽  
pp. 632-637
Author(s):  
Masih Falahatian

It is an assumption that different kinds of nutrition, diet, and functional foods might have different positive or negative effects on multiple sclerosis (MS), a neuroinflammatory disease of the central nervous system (CNS). This brief paper involved a study on various kinds of nutrition including salt, fat, dairy, fruit, and vegetables. At the end of this study, appropriate diets were evaluated for MS patients. Based on previous studies both on animal models and on MS patients, excessive dietary salt intake and animal fat had worsening effects on MS patients but fruit and vegetable intake helped the remission of MS and decreased the risk of developing it. There were, of course, conflicting results in different studies over the role of some nutrition in MS and future studies on larger numbers of cases were required to collect reliable results. As a result, at the end of this study and based on literature, it is suggested that a diet should be programmed by nutritionists containing fewer salt, fat, and dairy intake and more fruits and vegetables for MS patients in order to better management of the disease.



2021 ◽  
Vol 2021 (6) ◽  
Author(s):  
Emma J McMahon ◽  
Katrina L Campbell ◽  
Judith D Bauer ◽  
David W Mudge ◽  
Jaimon T Kelly


2006 ◽  
Vol 26 (3) ◽  
pp. 268-275 ◽  
Author(s):  
Charlotte Jones-Burton ◽  
Shiraz I. Mishra ◽  
Jeffrey C. Fink ◽  
Jeanine Brown ◽  
Weyinshet Gossa ◽  
...  


2015 ◽  
Vol 28 (9) ◽  
pp. 532-537 ◽  
Author(s):  
Samuel Amoah ◽  
Weiping Cao ◽  
Priya Ranjan ◽  
Patricia Greer ◽  
Wun-Ju Shieh ◽  
...  


2011 ◽  
Vol 2 (4) ◽  
pp. 615-618 ◽  
Author(s):  
KENICHIRO YASUTAKE ◽  
KAYOKO SAWANO ◽  
SHOKO YAMAGUCHI ◽  
HIROKO SAKAI ◽  
HATSUMI AMADERA ◽  
...  


2002 ◽  
Vol 283 (1) ◽  
pp. H353-H363 ◽  
Author(s):  
Francis A. Sylvester ◽  
David W. Stepp ◽  
Jefferson C. Frisbee ◽  
Julian H. Lombard

Rats were fed a low-salt (LS; 0.4% NaCl) or high-salt (HS; 4.0% NaCl) diet for 3 days, and the responses of isolated cerebral arteries to acetylcholine (ACh), the nitric oxide (NO)-dependent dilator bradykinin, and the NO donor 6-(2-hydroxy-1-methyl-2-nitrosohydrazino)- N-methyl-1-hex-anamine (NOC-9) were determined. ACh-induced vasodilation and NO release, assessed with the fluorescent NO indicator 4,5-diaminofluorescein (DAF-2) diacetate, were eliminated with the HS diet. Inhibition of cyclooxygenase, cytochrome P-450 epoxygenase, and acetylcholinesterase did not alter ACh responses. Bradykinin and NOC-9 caused a similar dilation in cerebral arteries of all groups. Arteries from animals on LS or HS diets exhibited similar levels of basal superoxide (O[Formula: see text]) production, assessed by dihydroethidine fluorescence, and ACh responses were unaffected by O[Formula: see text] scavengers. Muscarinic type 3 receptor expression was unaffected by dietary salt intake. These results indicate that 1) a HS diet attenuates ACh reactivity in cerebral arteries by inhibiting NO release, 2) this attenuation is not due to production of a cyclooxygenase-derived vasoconstrictor or elevated O[Formula: see text] levels, and 3) alteration(s) in ACh signaling are located upstream from NO synthase.



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