scholarly journals Treatment with .ALPHA.-Glucosidase Inhibitor for Severe Reactive Hypoglycemia. A Case Report.

2000 ◽  
Vol 47 (4) ◽  
pp. 437-442 ◽  
Author(s):  
SHINICHI TENO ◽  
YUKO NAKAJIMA-UTO ◽  
KAZUTAKA NAGAI ◽  
MADOKA SHIMIZU-SAITOH ◽  
HIROYUKI OZU ◽  
...  
2013 ◽  
Vol 27 (7) ◽  
pp. 403-404 ◽  
Author(s):  
Raymond J Playford ◽  
Charlotte Pither ◽  
Rui Gao ◽  
Stephen J Middleton

Postprandial reactive hypoglycemia, early satiety and diarrhea are well-recognized side effects following full or partial gastrectomy or gastric bypass. It has only recently been realized, however, that patients with normal gastric anatomy may experience similar symptoms and signs due to primary accelerated gastric emptying (Middleton syndrome). In previous case studies, patients responded well to the use of dietary modification (frequent small-volume meals) alone. The authors describe two patients with this syndrome who continued to experience symptoms of reactive postprandial hypoglycemia despite dietary intervention but became asymptomatic following the addition of the alpha-glucosidase inhibitor acarbose.


2008 ◽  
Vol 14 (39) ◽  
pp. 6087 ◽  
Author(s):  
Tatsuhiro Tsujimoto ◽  
Erika Shioyama ◽  
Kei Moriya ◽  
Hideto Kawaratani ◽  
Yasuyo Shirai ◽  
...  

2007 ◽  
Vol 122 ◽  
pp. S68
Author(s):  
Masamitsu Iwasa ◽  
Hiroyuki Kobayashi ◽  
Shinji Yasuda ◽  
Narentuoya Bao Itta Kawamura ◽  
Takahiko Yamaki ◽  
...  

2016 ◽  
Vol 17 (2) ◽  
pp. 123
Author(s):  
Sri Pujiyanto ◽  
Rejeki Siti Ferniah ◽  
Sunarno S

Alpha-glucosidase inhibitors are compounds that can prevent the digestion of complex carbohydrates into glucose, so potentially used as a diabetes drug. This study aims to examine the production and extraction of alpha-glucosidase inhibitor compound from Isolate Aktinomiset JP-3 from the sea. The supernatant obtained from the culture of the JP-3 isolate was extracted using various solvents to obtain the active compound. The solvents used were chloroform, methanol, and ethyl acetate. An assay of inhibitor activity of the α-glucosidase using p-nitrophenyl α-D-glucopyranoside substrate. The activity of the enzyme is measured based on the absorbance of p-nitrophenol produced from the breaking reaction of the substrate. The results showed that extraction of alpha-glucosidase inhibitor compound with ethyl acetate yielded extract with highest inhibitor activity. Keywords: alpha-glucosidase inhibitors, actinomycetes, diabetes, extraction, fractionation


1998 ◽  
Vol 13 (12) ◽  
pp. 1201-1206 ◽  
Author(s):  
TAKENAO HASEGAWA ◽  
MASASHI YONEDA ◽  
KIMIHIDE NAKAMURA ◽  
KUNIYO OHNISHI ◽  
HIROYUKI HARADA ◽  
...  

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