Quality of life in the elderly after major lung resection for lung cancer

BACKGROUND: Patients with lung cancer often experience a reduction in exercise tolerance, muscle weakness and decreased quality of life. Although the effectiveness of pulmonary rehabilitation programs is well recognized in other forms of cancers and in many pulmonary diseases, few researchers have studied its impact in patients with lung cancer, particularly in those awaiting lung resection surgery (LRS).OBJECTIVES: To investigate the feasibility of a short, home-based exercise training program (HBETP) with patients under investigation for non-small cell lung cancer and potential candidates for LRS, and to determine the effectiveness of this program on exercise tolerance, skeletal muscle strength and quality of life.METHODS: Sixteen patients with lung cancer awaiting LRS participated in a four-week HBETP including moderate aerobic activities (walking and cycling) and muscle training performed three times weekly. Before and after the intervention, a cardiopulmonary exercise test, a 6 min walk test and the assessment of muscle strength and quality of life were performed.RESULTS: Thirteen patients completed the four-week HBETP and all the patients completed >75% of the prescribed exercise sessions. The duration of the cycle endurance test (264±79 s versus 421±241 s; P<0.05) and the 6 min walk test distance (540±98 m versus 568±101 m; P<0.05) were significantly improved. Moreover, the strength of the deltoid, triceps and hamstrings were significantly improved (Δ post-pre training 1.82±2.83 kg, 1.32±1.75 kg and 3.41±3.7 kg; P<0.05, respectively).CONCLUSION: In patients with lung cancer awaiting LRS, HBETP was feasible and improved exercise tolerance and muscle strength. This may be clinically relevant because poor exercise capacity and muscle weakness are predictors of postoperative complications.

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Predictors of quality-of-life improvement following pulmonary resection due to lung cancer

Sao Paulo Medical Journal ◽

10.1590/s1516-31802007000100009 ◽

2007 ◽

Vol 125 (1) ◽

pp. 46-49 ◽

Cited By ~ 14

Author(s):

Ivete Alonso Bredda Saad ◽

Neury José Botega ◽

Ivan Felizardo Contrera Toro

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Social Life ◽

Short Form ◽

Lung Resection ◽

Lung Cancer Diagnosis ◽

Sf 36 ◽

Life Improvement ◽

The Impact

CONTEXT AND OBJECTIVE: There is increasing involvement of health professionals in organizing protocols to determine the impact of lung surgery on functional state and activities of daily living, with the aim of improving quality of life (QoL). The objective of this study was to investigate predictors of QoL improvement among patients undergoing parenchyma resection due to lung cancer. DESIGN AND SETTING: Prospective study, at teaching hospital of Universidade Estadual de Campinas (Unicamp). METHODS: 36 patients with lung cancer diagnosis were assessed before surgery and on the 30th, 90th and 180th days after surgery. The Short-Form Health Survey (SF-36) was used as the dependent variable. The independent variables were the Hospital Anxiety and Depression (HAD) scale, a six-minute walking test (6-MWT), a visual analogue scale for pain, forced vital capacity (FVC), type of surgery and use of radiotherapy and chemotherapy. Generalized estimation equations (GEE) were utilized. RESULTS: The median age for these 20 men and 16 women was 55.5 ± 13.4 years. Both FVC and 6-MWT were predictors of improvement in the physical dimensions of QoL (p = 0.011 and 0.0003, respectively), as was smaller extent of surgical resection (p = 0.04). The social component of QoL had improved by the third postoperative month (p = 0.0005). CONCLUSION: The predictors that affected QoL positively were better FVC and 6-MWT results and less extensive lung resection. Three months after the surgery, an improvement in social life was already seen.

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Quality of Life Before and After Major Lung Resection for Lung Cancer: A Prospective Follow-Up Analysis

The Annals of Thoracic Surgery ◽

10.1016/j.athoracsur.2007.04.019 ◽

2007 ◽

Vol 84 (2) ◽

pp. 410-416 ◽

Cited By ~ 89

Author(s):

Alessandro Brunelli ◽

Laura Socci ◽

Majed Refai ◽

Michele Salati ◽

Francesco Xiumé ◽

...

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Lung Resection ◽

Before And After

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Clinical and quality of life outcomes following anatomical lung resection for lung cancer in high-risk patients

Annals of Thoracic Medicine ◽

10.4103/atm.atm_385_16 ◽

2017 ◽

Vol 12 (2) ◽

pp. 83 ◽

Cited By ~ 3

Author(s):

Henrietta Wilson ◽

David Gammon ◽

Tom Routledge ◽

Karen Harrison-Phipps

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

High Risk ◽

Lung Resection ◽

Life Outcomes ◽

High Risk Patients ◽

Quality Of Life Outcomes ◽

Risk Patients

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Effects of a Multicomponent Exercise Program in Older Adults with Non-Small-Cell Lung Cancer during Adjuvant/Palliative Treatment: An Intervention Study

Journal of Clinical Medicine ◽

10.3390/jcm9030862 ◽

2020 ◽

Vol 9 (3) ◽

pp. 862

Author(s):

Ilem D. Rosero ◽

Robinson Ramírez-Vélez ◽

Nicolas Martínez-Velilla ◽

Bernardo Abel Cedeño-Veloz ◽

Idoia Morilla ◽

...

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Adjuvant Therapy ◽

Cognitive Functioning ◽

Palliative Treatment ◽

Exercise Program ◽

The Elderly ◽

Small Cell ◽

Small Cell Lung

Clinical intervention studies support the efficacy and safety of exercise programs as a treatment modality for non-small-cell lung cancer (NSCLC) during adjuvant/palliative treatment, but the effectiveness of real-world oncogeriatric services is yet to be established. We aimed to examine the effects of a 10-week structured and individualized multicomponent exercise program on physical/cognitive functioning and mental wellness in elderly patients with NSCLC under adjuvant therapy or palliative treatment. A non-randomized, opportunistic control, longitudinal-design trial was conducted on 26 patients with NSCLC stage I–IV. Of 34 eligible participants, 21 were allocated into two groups: (i) control group (n = 7) received usual medical care; and (ii) intervention group (n =19) received multicomponent program sessions, including endurance, strength, balance, coordination and stretching exercises. Tests included the Short Physical Performance Battery (SPPB), 5-m habitual Gait Velocity Test (GVT), Timed Up & Go Test (TUG), 6-Min Walk Test (6MWT), independence of activities in daily living (IADL), muscular performance, cognitive function, and quality of life, which were measured at baseline and after 10 weeks of the program. Results revealed a significant group×time interaction for SPPB (p = 0.004), 5-m GVT (p = 0.036), TUG (p = 0.007), and muscular performance (chest and leg power; p < 0.001). Similarly, significant changes were observed between groups for cognitive functioning (p = 0.021) and quality of life for EUROQoL 5D (p = 0.006). Our findings confirm that a multicomponent exercise program improves measures of physical/cognitive functioning and quality of life in the elderly with NSCLC under adjuvant therapy or palliative treatment. This is an interesting and important study that adds to our current body of knowledge on the safety of exercise interventions, especially in the elderly with solid tumors.

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Differential conditions of quality of life in the elderly: Gender differences

PsycEXTRA Dataset ◽

10.1037/e578442014-149 ◽

2011 ◽

Author(s):

Paola Bully ◽

Paula Elosua ◽

Josu Mujika

Keyword(s):

Quality Of Life ◽

Gender Differences ◽

The Elderly

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