scholarly journals Differential diagnosis between occupational chronic intoxication with organic solvents and ethanol abuse by biological markers. Case report and literature review

2016 ◽  
Vol 22 (4) ◽  
pp. 217-221
Author(s):  
Agripina Rascu ◽  
Eugenia Naghi ◽  
Oana Cristina Arghir ◽  
Laura Moise ◽  
Marina Otelea

AbstractGiven the occupational exposure to substances contained in petroleum heated to high temperature, cholestatic liver disease, neurological signs and symptoms can occur. We present a case report of a male patient with no tobacco exposure or alcohol use, but with prolonged occupational exposure to petroleum vapours and natural gases like methane, propane butane who developed liver and neurologic disease, in the absence of protective equipment. Delayed diagnosis was established after 9 years of the first symptoms occurrence. Differential diagnosis with alcoholic etiology was considered and biological biomarkers were useful.

2021 ◽  
Author(s):  
Christina Weise ◽  
Matthias C. Schulz ◽  
Karin Frank ◽  
Marcel Cetindis ◽  
Bernd Koos ◽  
...  

Abstract Lyme disease is the most frequent tick-borne infectious disease in Europe. It often presents with a wide variety of symptoms. For this reason, affection of the temporomandibular joint (TMJ) caused by Lyme disease (LD) can be misdiagnosed as a common temporomandibular disorder (TMD). The purpose of this case report of a 25-year old woman presenting to the Departments of Orthodontics and Maxillofacial Surgery with extensive symptoms of Temporomandibular Disorder is to illustrate the delayed diagnosis of Lyme disease, which was only made after extensive therapy of the temporomandibular joint. The specialist literature only reports a few cases of patients suffering from Lyme disease with TMJ manifestations. This case report and the relevant literature review aim to emphasize the importance of accurate request of medical history and differential diagnosis of acute TMJ arthritis and arthralgia. Early interdisciplinary diagnosis of Lyme disease and early antibiotic therapy are essential to avoid misdiagnosis and unnecessary, sometimes invasive, therapies.


2021 ◽  
Vol 14 (2) ◽  
pp. e240146
Author(s):  
Anna Li ◽  
Fadak Mohammadi ◽  
Helen Crocker

This case report presents the unusual complication of bilateral temporomandibular joint dislocation following bronchoscopy, highlighting the importance of recognising it as a differential diagnosis in patients having jaw symptoms. The delayed diagnosis in this case resulted in multiple unsuccessful reduction attempts under sedation, which added to the distress of the patient. Notably, the procedure yielded a rare diagnosis for the patient that intrinsically changed the management of her breast cancer.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1984858
Author(s):  
John J Eicken ◽  
Dustin Morrow

Introduction: Compartment syndrome is a serious condition that requires prompt diagnosis, specialty consultation, and definitive management to prevent significant morbidity. Traditionally, compartment syndrome is identified by physical exam findings including the presence of pain, pallor, paresthesia, pulselessness, and paralysis involving the affected limb. Identifying the presence of compartment syndrome prior to the onset of signs that portend a poor outcome (i.e. pallor, pulselessness, and paralysis) can be challenging since many other less serious traumatic conditions can lead to paresthesia and pain in a limb. Bedside ultrasound is increasingly being utilized by emergency providers to expedite identification of various emergent diagnoses and guide care for patients who present to emergency departments. Bedside ultrasound allows emergency providers to visualize pathologic processes occurring that may be difficult to identify through traditional physical exam findings. This case report highlights the use of bedside ultrasound to promptly identify the presence of a traumatic thigh hematoma, which led to expedited advanced imaging and specialty consultation for compartment syndrome prior to the onset of physical exam findings consistent with compartment syndrome. Conclusion: The identification of compartment syndrome in the early stages is challenging given the overlap of signs and symptoms with other less emergent conditions. Early diagnosis of compartment syndrome is important to decrease morbidity, which can result from a delayed diagnosis of compartment syndrome. To our knowledge, this is the first case report to describe the use of bedside ultrasound to aid in the diagnosis of compartment syndrome and accelerate the care for a patient who presented with a traumatic thigh hematoma, which rapidly progressed to compartment syndrome and required emergent operative intervention.


Author(s):  
Folasade D. H. Olalere ◽  
Abraham F. Adeyeye ◽  
Taiwo O. Kuye ◽  
Adeyemi F. Tijani ◽  
Fatimah A. Rabiu ◽  
...  

<p><span>Primary extra nodal non-Hodgkin lymphomas of the genital tract are uncommon, and involvement of the uterine corpus is not only extremely rare but lacks pathognomonic signs and symptoms, resulting in delayed diagnosis and treatment. This prompted this case report of a multiparous lady who presented with recurrent bleeding per vaginam and progressive abdominal swelling that was initially suspicious of being uterine sarcoma, but histological analysis of excised sample was diagnostic of non-Hodgkin lymphoma of the uterus. The report also highlights the challenges to diagnosis and management in a resource poor setting where advanced diagnostic aids are not readily accessible. The diagnosis of uterine non-Hodgkin lymphoma, though uncommon, should be considered in any patient with an abdominal/pelvic mass and/or abnormal bleeding per vaginam. </span></p>


2012 ◽  
Vol 130 (6) ◽  
pp. 405-408 ◽  
Author(s):  
Rodrigo Antonio Brandão Neto ◽  
Jozélio Freire de Carvalho

CONTEXT: Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. CASE REPORT: We report the case of a woman with EIB who developed Addison's disease during treatment with anti-tuberculosis drugs with good response to glucocorticoid replacement. The diagnosis was obtained through the clinical picture, positive tuberculin test and positive BCG (bacillus Calmette-Guérin) test on the histological sample. Anti-tuberculosis drugs and glucocorticoid replacement led to disappearance of the signs and symptoms. CONCLUSIONS: This is the first description of an association between EIB and Addison's disease. It should be borne in mind that tuberculosis is an important etiological factor for Addison's disease.


2002 ◽  
Vol 36 (3) ◽  
pp. 440-443 ◽  
Author(s):  
Roy R Reeves ◽  
James E Mack ◽  
John J Beddingfield

OBJECTIVE: To report a case of a neurotoxic syndrome in a patient undergoing concomitant treatment with risperidone and fluvoxamine. CASE REPORT: A 24-year-old African American woman hospitalized for psychosis was unresponsive to risperidone. Because of obsessive symptoms, low doses of fluvoxamine were added to her treatment regimen. Within 2 days, she developed confusion, diaphoresis, diarrhea, hyperreflexia, and myoclonus, which then progressed to rigidity, fever, and unresponsiveness, requiring endotracheal intubation. Symptoms resolved over 10 days with discontinuation of medication, hydration, and bromocriptine 5 mg 3 × daily. Ultimately, she was treated with olanzapine and fluvoxamine without adverse effects. DISCUSSION: This represents the first reported case of a neurotoxic syndrome secondary to treatment with risperidone and fluvoxamine. Differential diagnosis between neuroleptic malignant syndrome (NMS) and serotonin syndrome (SS) could not be accurately determined because of the overlap of signs and symptoms of both syndromes. NMS and SS may represent different aspects of a more generalized neurotoxic syndrome. This could be an important consideration in formulating treatment for neurotoxic syndromes. CONCLUSIONS: Clinicians should be aware of potentially serious adverse reactions that may occur during concomitant treatment with antipsychotics and selective serotonin-reuptake inhibitors.


2021 ◽  
Vol 14 (4) ◽  
pp. 1413-1416
Author(s):  
Ashwag Yagoub Aloyouny

Oral hygiene products (OHP) are recommended to maintain the teeth and health of the oral cavity tissues by assisting in lowering the plaque level as well as the opportunistic flora. Oral hygiene products could cause oral health problems that may vary in severity. Due to the availability of over-the-counter (OTC) medications and lack of knowledge, customers may misuse these products. An oral hygiene product is a double-edged sword; a customer would develop side effects from it without even knowing or correlating the source. Many signs and symptoms may appear on the patients such as oral and perioral burning sensations, swelling, erythema, dysgeusia, and dysphagia. To our knowledge and based on the review of English literature through PubMed Midline, this is the first case report of misuse because of an over-the-counter oral hygiene product in which the patient used a mouthwash continuously and aggressively for 15 days without knowing of its side effects. This case report presents an eighty-two-year-old, male patient who complained of pain, burning, swollen, and dry mouth and lips. The author discussed the most common ingredients of oral mouthwashes. Some active ingredients may irritate the oral mucosa and lips. Also, the author discussed the possible differential diagnosis of painful, sensitive, burning, swollen, and dry mouth and lips. This report is intended as an overview of a rare and unusual oral condition associated with the misuse of OTC oral hygiene products. The findings of the present study necessitated the need for clear verbal and written instructions to be provided to the patients before recommending or prescribing any type of medication.


2021 ◽  
Vol 14 (4) ◽  
pp. 1398-1401
Author(s):  
Ashwag Y Aloyouny

Clear Cell Odontogenic Carcinoma (CCOC) is a slow-growing, locally invasive odontogenic tumor affecting the jaws. It usually has confusing clinical characteristics, radiographical and histological features, making its recognition more challenging. In (2005), the WHO has reclassified CCOC as a malignant odontogenic tumor due to its aggressive behavior. This case report is about a woman who aged 42 years old, experienced swelling of the lower jaw and complained of paresthesia of the lips for two years. Radiographic findings showed an extensive, large, multilocular radiolucency lesion associated with scalloping, non-sclerotic border, and crossing the midline of the mandible. Histopathologically, the high-power view illustrated lobules of clear epithelial cells with clear cytoplasm. A review of English literature in PubMed Medline revealed few similar cases of CCOC affecting the mandible. The definitive diagnosis was consistent with CCOC; therefore, the patient was admitted to the hospital and surgical resection of the mandibular tumor was performed under general anesthesia. Long-term follow-up visits showed no signs of recurrence or post-surgical complications. We explain the signs and symptoms of CCOC such as symptomatic or asymptomatic jaw swelling, teeth loosening, displacement and mobility of teeth, and thinning of the mandible. Also, differential diagnosis and the nature of CCOC under the microscope were discussed and explained. The presentation of clear cell tumors is challenging, and it needs a meticulous investigation to determine the type of the tumor for proper diagnosis and management. CCOC should be included in the differential diagnosis list of jaw swelling that associated with slow-growing mass and paresthesia in the affected jaw.


2017 ◽  
Vol 57 (2) ◽  
pp. 108 ◽  
Author(s):  
Indra Ihsan ◽  
Eka Agustia Rini

Delayed diagnosis of congenital hyporhyroidism (CH) remains a serious problem. A retrospective analysis of 1,000 CH cases in Turkey found a mean age of 49 months at the time of clinical diagnosis. Only 3.1% of cases were diagnosed during the neonatal period and 55.4% were diagnosed after 2 years of age.1 In Cipto Mangunkusumo Hospital, Jakarta, 53% cases were diagnosed at 1-5 years, 3.3% at 6-12 years, and 6.7% after 12 years of age, while the remainder were diagnosed at < 1 year of age.2 The majority of affected children exhibit signs and symptoms that are highly non-specific, as most infants with CH are asymptomatic at birth, and only 5% of cases can be diagnosed based on clinical examination during the first day of life.3 The other factors that contribute to delayed diagnosis are uneducated parents, who do not notice or dismiss the importance of mild/moderate deviations in physical and mental growth, as well as constipation, feeding difficulties, or other vague, non-specific symptoms in infancy. Parents are often unaware of the importance of early diagnosis and commencement of therapy for CH.4


2002 ◽  
Vol 3 (1) ◽  
pp. 16-26 ◽  
Author(s):  
Terri S.I. Tilliss ◽  
John McDowell

Abstract Recurrent aphthous stomatitis (RAS) and recurrent intraoral herpes (RIH) are the two most commonly presenting oral lesions in the dental setting. It is critical that the oral health professional be able to accurately discriminate between these disorders. To facilitate the differential diagnosis between RAS and RIH, important components of assessment are discussed. These include: prodromal signs and symptoms, lesion location, and appearance of the initial and mature lesion. The comparative etiology, prevalence, pathogenesis, and treatment considerations for these lesions are presented. A familial case report is provided. Citation Tilliss TSI, McDowell JD. “Differential Diagnosis: Is It Herpes or Aphthous?” J Contemp Dent Pract 2002 Feb;(3)1: 001-015.


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