scholarly journals Developmental anomalies of the right hepatic lobe: systematic comparative analysis of radiological features

2017 ◽  
Vol 12 (1) ◽  
pp. 489-500
Author(s):  
Li-Li Liang ◽  
Hao-Jie Li ◽  
Yao Hu ◽  
Anqin Li ◽  
Daoyu Hu ◽  
...  

AbstractAimTo investigate the radiological characteristics of developmental anomalies of the right hepatic lobe and to systematically compare the efficiency of CT, MR and ultrasound (US) imaging in revealing characteristics of these disorders.MethodsThis retrospective study was approved by the institutional review board, and the requirement for informed consent was waived. CT, MR or US imaging and clinical data of 43 cases with developmental anomalies of the right hepatic lobe were independently reviewed by two experienced radiologists. Systematic comparative analysis of the CT, MR, and US imaging data indicating the main signs of right lobe aplasia or hypoplasia were obtained. Then, c2tests were performed to compare the results, considering P<0.05 as the significance threshold.ResultsAgenesis of the right hepatic lobe was observed in two cases. The main imaging features were agenesis of the right lobe and the absence of the right branch of the portal vein and hepatic artery, although one patient exhibited right diaphragm agenesis and a diaphragmatic hernia. Aplasia or hypoplasia of the right hepatic lobe was observed in 41 patients, and among these patients, the main radiological characteristics were as follows: right lobe volume reduction and stenosis of the right portal vein (41 cases, 100%), ectopic gallbladder (39 cases, 95%), left lobe hypertrophy (39 cases, 95%), left portal vein thickening (37 cases, 90%), dextral displacement of the first hepatic portal (32 cases, 78%), caudate lobe hypertrophy (16 cases, 39%), cholelithiasis (12 cases, 29%), portal hypertension (14 cases, 34%), tumor complications (11 cases, 27%), liver abscess (2 cases, 5%), concurrent intrahepatic bile pneumatosis (5 cases, 12%), dysplasia of the right hepatic bile duct (2 cases, 5%), and Budd-Chiari syndrome (2 cases, 5%). Comparative analysis of the main signs of right lobe hypoplasia revealed no significant difference in overall diagnostic efficiency between CT, MRI and US (CT VS MR, X2= 6.28, P = 0.985; CT VS US, X2= 11.2, P = 0.797; US VS MR, X2= 8.48, P = 0.903).ConclusionThe main radiological characteristics of developmental anomalies of the right hepatic lobe were right lobe volume reduction, stenosis of the right portal vein, ectopic gallbladder, left lobe hypertrophy and dextral displacement of the first hepatic portal. By combining the data from imaging methods (CT, MRI, and US) with clinical data, developmental anomalies of the right hepatic lobe can be relatively accurately diagnosed. The results of this systematic comparative analysis may improve our understanding of this disease.

2018 ◽  
Vol 41 (2) ◽  
pp. 94-99
Author(s):  
Khalid Ibrahim Abd Al-Khazraji

     This study was conducted to compare some of anatomical features and histological structure of the liver in three species of birds that varied in their size, taxonomy, and food environment. The study revealed that the liver in the mallard, gull and white-eared bulbul was bilobed big gland, and the left lobe was smaller than the right one. It was observed that the two lobes in mallard were undivided, while the right lobe in gull has two parts, whereas the left lobe in white-eared bulbul is subdivided into two parts. Histologically, the liver capsule in gull appeared thicker than other two species. The hepatic parenchyma was not shown to be clearly defined lobules in three species. The hepatocytes were organized radially around the central vein as plates or cords of one-two cell thick in mallard and gull, and of two-several cell thick in white-eared bulbul, and those plates were separated by blood sinusoids. It turned out that the hepatic portal triads were less numerous in white-eared bulbul compared with other two species. It was found that there are differences in measurements of some histological structures of the liver among the three species.


Author(s):  
Camila Ribeiro Martins Schwantes ◽  
Bruna Leticia Miler ◽  
Ana Cristina Oliveira Gimenes ◽  
Geisy Natiele Borges Ribeiro ◽  
Suellen Keyze Almeida Lima ◽  
...  

Riedel's lobe (ectopic lobe), also known as the accessory hepatic lobe, consists of an anatomical variation characterized by a tongue-shaped protrusion on the visceral surface of the liver right lobe, fixed by a pedicle. This variant draws attention in the clinical practice, as it can be mistaken for a tumor due to its elongated aspect. The aim of this research was to conduct a study on the anatomical characteristics and clinical and functional peculiarities of the accessory hepatic lobe. The paper is based on a integrative review and observational study on a cadaveric specimen. A cadaver with anatomical variation was used. Data were collected in PubMed, Scielo, and VHL. 257 articles were found in the databases, but only 13 were used for research. In careful review, two rare cases of the accessory lobe in the left lobe of the liver, hypoplastic left lobes, and agenesis of the right hepatic lobe, and often the clinical picture without changes in signs and symptoms were found. These morphological abnormalities' clinical impact is limited in the absence of underlying liver disease, cirrhosis, or known cancer. In case of complications or after the diagnosis of pedunculated tumors in the liver, laparoscopy is well indicated for removing these lobes or tumors.


2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Hiroki Sato ◽  
Kiyoaki Tsukahara ◽  
Ray Motohashi ◽  
Midori Wakiya ◽  
Hiromi Serizawa ◽  
...  

Background. Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe. Methods and Results. We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma. Conclusions. All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Parviz Mardani ◽  
Ali Talebi Ezabadi ◽  
Bahareh Sedaghat ◽  
Seyed Mahmoud Sadjjadi

Abstract Background Cystic echinococcosis (CE)/hydatidosis is an important neglected parasitic zoonotic disease caused by the metacestode of Echinococcus granulosus s.l. The present study was designed to identify the pulmonary CE species/genotypes in isolated human underwent to surgery in our center in Southern Iran. Methods The study population of this study were all patients in Fars province who were admitted to Namazi Hospitals for pulmonary hydatid cyst surgery. Thoracic surgery was performed in the thoracic ward and the cyst/s was removed by open surgery via posterolateral or lateral thoracotomy. DNA was extracted from the germinal layer or the protoscoleces. PCR technique was performed using the cytochrome C oxidase subunit1 (cox1) gene, and the products were sequenced. Results A total of 32 pulmonary hydatid cyst samples were collected from 9 (28%) female and 23 (72%) male aged from 4 to 74 years old. A total of 18(56%) cyst/s were in the left lobe and 14 (44%) cysts in the right lobe. Sequence analysis of the cysts showed that 24 samples (75%) were E. granulosus s.s (G1-G3) genotype and 8 (25%) were E. canadensis (G6/G7) genotype. Conclusion E.granulosus s.s genotype was the most prevalent genotype followed by E. canadensis (G6/G7) genotype. There was no significant statistical correlation between cysts’ size, location, genotype strain, and patients’ age and gender.


2018 ◽  
Vol 08 (02) ◽  
pp. 72-76
Author(s):  
Mahrukh Kamran ◽  
Sahar Mubeen ◽  
Iffat Raza ◽  
Sanobar Bughio ◽  
Hira Waseem ◽  
...  

Objectives: To determine the effect of serum TSH on thyroid dimensions of each lobe and to measure the amount of effect of per unit increase in serum TSH on thyroid dimensions of each lobe in euthyroids. Study Design: It was a cross-sectional study. Setting: The study was conducted at Ziauddin University Hospital, Clifton, Karachi. Methodology: Healthy participants aged 21 years and above were included through convenient sampling. Serum Thyroid stimulating hormone was evaluated and ultrasound of thyroid gland TG of 192 euthyroid participants was performed. Spearman correlation and regression analysis was applied to evaluate the relationship between TSH and TG dimensions Results: Relationship of increase in serum TSH with decrease in light lobe AP dimension was most significant. (r= -0.142 P-Value=0.001) and CC dimension least significant (r= -0.0098 P-Value=0.001). Where as in the left lobe AP dimension decreases significantly with increase serum TSH (r= -0.147 P-value=0.001). 11.7% of total variation in AP dimension, 3.5% of total variation in ML dimension and 6.5% of total variation in CC dimension in right lobe thyroid are because of serum TSH. While 9.5% of the total variation in AP dimension in left lobe is also due to serum TSH. Conclusion: Negative and significant correlation between serum TSH and thyroid dimensions was observed. Serum TSH inversely and significantly affects all the dimensions of the right lobe and only one dimension in the left lobe


2021 ◽  
pp. 7-9
Author(s):  
Seena N ◽  
Lekha K S ◽  
Arivuselvan S

Background: Variations of the Hepatic Portal Vein are encountered during abdominal surgeries. Aim: The present study is an observational study of the extrahepatic part of Portal Vein & its variations on cadavers. Materials & Methods: A total of 50 upper abdomen dissections were carried out to delineate extra-hepatic Portal Vein anatomy. The Results: mean length of Portal Vein was 5.96cm. The mean diameter of Portal Vein was 1.35cm. The most common type of formation of Portal Vein was Type I, found in 64%. The Right Gastric Vein commonly emptied into the trunk of the Portal Vein. The Left Gastric Vein commonly emptied into the trunk of the Portal Vein in 87.18%. The most common type of Portal Vein termination was Extra-Hepatic, found in 76% of 50 dissections. The Bifurcation pattern was the most common pattern of Portal Vein termination, found in 94% of dissections. The ndings of the present Conclusion: study highlight the variations that may occur in the hepatic portal venous system in its extra-hepatic part. Sound knowledge of portal venous anatomy is needed for success in the surgeries of the liver & adjacent viscera.


2019 ◽  
Vol 160 (42) ◽  
pp. 1677-1681
Author(s):  
Ákos Balázs ◽  
Tamás Vass ◽  
Dávid Tárnoki ◽  
Zsolt Baranyai

Abstract: Migration of swallowed foreign bodies from the gastrointestinal tract is a rare phenomenon compared with the total number of ingestions. In the reported two cases, the serious septic condition indicated urgent surgical intervention. We found a piece of wire swallowed a few months earlier in the right lobe of the liver and the retroperitoneum in case one, and a piece of wire in the pericardium, which migrated from the stomach through the left lobe of the liver, in case two. Abscesses and phlegmonae were found in the retroperitoneum and then in the femoral region requiring a reoperation in case one, and in the liver and pericardium in case two. After the evacuation of abscesses, both patients made full recovery. Diagnostic difficulties and therapeutic challenges served the reasons to present these cases. Orv Hetil. 2019; 160(42): 1677–1681.


Author(s):  
Stephanie M. George ◽  
Diego R. Martin ◽  
Don P. Giddens

The incidence of cirrhosis, the end stage for many liver diseases, is rising and with it the need for better understanding of the progression of the disease and diagnostic techniques. The authors have noted that liver disease occurs preferentially in the right side of the liver which is the largest lobe. One hypothesis is that this is due to the composition of the blood that supplies the right lobe. The liver is fed by both the hepatic artery and the portal vein with the portal vein contributing about 80% of the blood supply. The portal vein (PV) is supplied by the superior mesenteric vein (SMV), which drains blood from the digestive track, and the splenic vein (SV), which drains blood from the spleen. Since the blood in the SMV is coming from the digestive track, it carries toxins and items absorbed during digestion. Toxins such as alcohol are known to damage the liver. Thus, our hypothesis is that the majority of the SMV flow feeds into the right portal vein and ultimately the right lobe of the liver. This study seeks to assess the validity of our hypothesis in four subjects by creating subject specific models in two normal subjects and two patients and using computational fluid dynamics (CFD) to calculate the SMV contribution to the right portal vein.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Lucas Souto Nacif ◽  
Yuri dos Santos Buscariolli ◽  
Luiz Augusto Carneiro D'Albuquerque ◽  
Wellington Andraus

Introduction. Agenesis of the right lobe of the liver is a rare finding and was defined as the absence of liver tissue on the right side, with preservation of the middle hepatic vein, without previous disease or surgery. It is usually an incident finding reveled by imaging exams or during abdominal surgery.Case Report. A 32-year-old male patient was admitted to the hospital for abdominal discomfort and loss of appetite. Imaging studies revealed the absence of the right hepatic lobe and hypertrophied left hepatic segments.Discussion. Anomalies of hepatic morphology are rare and correspond to developmental defects during embryogenesis, are a rare diagnosis, and are generally diagnosed incidentally based on imaging. Agenesis or hypoplasia of the right lobe may predispose the patient to the development of portal hypertension and esophageal varices. Surgical knowledge of such anatomical agenesis is necessary for surgical planning, for the appropriate identification of intraoperative surgical findings, and for the design of the postoperative approach to therapy.Conclusion. Agenesis of the right hepatic lobe is a rare condition. We want to highlight the importance of understanding the condition. Surgeons must recognize the entity in order to deal appropriately with the findings.


2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Ümit Yaşar Ayaz ◽  
Sevin Ayaz ◽  
Mehmet Ercüment Döğen ◽  
Arman Api

Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of thyroid gland fails to develop. It is much rarer in males. There is a higher incidence of associated thyroid disorders in patients with thyroid hemiagenesis; therefore early and prompt diagnosis is important for children. We present the ultrasonographic and scintigraphic findings of thyroid hemiagenesis in an eight-year-old-boy. On ultrasonography (US), left lobe of the thyroid gland could not be demonstrated and the right lobe showed minimal hyperplasia. Its echogenicity was normal and no nodule was seen. On thyroid scintigraphy, left lobe of thyroid gland or any ectopic thyroid tissue could not be demonstrated, while the right lobe showed minimal hyperplasia. Without performing any invasive procedure, we enrolled the child in a follow-up program with the guidance of US and scintigraphy, which were effective both in making the final diagnosis of thyroid hemiagenesis and in evaluating the current status of the present thyroid tissue. In conclusion, if only one thyroid lobe is detected in a pediatric case initially with US or scintigraphy, the diagnosis of thyroid hemiagenesis should be suggested and, before any unnecessary or invasive attempt, the other complementary method (scintigraphy/US) should be performed.


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