scholarly journals Changes in Health-Related Quality of Life in Greek Adult Patients Two Years after Successful Renal Transplantation

2016 ◽  
Vol 14 (1) ◽  
pp. 30-33
Author(s):  
Aikaterini Balaska ◽  
Dimitris Pistolas ◽  
Maria Koukoulaki ◽  
Dimitris Alassas ◽  
Spiros Drakopoulos ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Physical Functioning ◽  
General Health ◽  
Hemodialysis Patients ◽  
Transplant Recipients ◽  
Transplant Patients ◽  
Sf 36 ◽  
Scale Scores ◽  
Related Quality

AbstractIntroduction. This study was undertaken to compare and evaluate the heath-related quality of life (HRQOL) in Greek adult transplant recipients before and 2 years after successful renal transplantation (RT). The SF-36 survey score was used. Methods. Eighty-five Greek hemodialysis patients underwent RT at the Transplant Unit of Evangelismos General Hospital of Athens, including 44 men and 41 women (mean age 43.8 years; range 21-59 years). The scale scores of a Greek version of the SF-36 survey were compared between the transplant and the hemodialysis patients. We also examined the relationships of the scale scores with the patients′ age and the type of donor. Results. According to the SF-36 health survey, transplant recipients had better results for general health perception (p≤0.001), role-physical functioning (p≤0.01), role-emotional functioning (p≤0.01), and vitality (p≤ 0.01). In addition, the scale score of physical functioning, general health and vitality of the patients who were younger than 30 years at the time of transplantation were significantly higher than those of the patients who were older than 30 years, while the scores of bodily pain, general health, and physical functioning were significantly lower in cadaveric graft recipients compared with living-related recipients. Conclusions. The SF-36 health survey is a validated and comprehensive instrument for evaluating renal transplant patients′ HRQOL. Our data demonstrated an improvement in HRQOL in renal transplant patients 2 years after successful renal transplantation. The data also confirmed that the recipients′ age at transplantation and the type of donor were important factors affecting the HRQOL.

Abstract 13633: Predictors of Mental and Physical Health Outcomes of Patients Undergoing an Appointment-based Cardiac Rehabilitation Program

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Catherine Xie ◽  
Sean Fournier ◽  
Susan Hiller ◽  
Joyce Oen Hsiao ◽  
Rachel P Dreyer
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Cardiac Rehabilitation ◽  
General Health ◽  
Health Related Quality ◽  
Sf 36 ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related

Introduction: Cardiac rehabilitation (CR) is an evidence-based program to improve secondary prevention outcomes for patients with cardiovascular disease (CVD). Lower health-related quality of life is a known risk factor for worse CVD outcomes. We examined the effects of a patient-driven appointment-based CR program on health-related quality of life. Methods: We utilized data from the Yale New-Haven Health (YNHH) CR program over a 6-year period (2012-2017). Data was collected on patient demographics, clinical characteristics and socioeconomic status. The Medical Outcome Short-Form General Health Survey (SF-36) was used to measure general health status. We evaluated SF-36 score changes pre and post CR with paired T-tests and conducted logistic regression analysis to examine predictors of improvements in health-related quality of life. Results: Over the 6-year study period, a total of 2,135 patients (27.9% women, mean age 65±12 years) were enrolled in the CR program. Patients demonstrated significant improvements in both the SF-36 physical, mental and health transition components (P<0.001) (Table) . In particular, patients had significant improvement in the social functioning domain (measures limitations patients see in their ability to participate in social activities due to physical/emotional issues), with an increase of 23.3 points out of 100. Physician-reported patient stress and/or depression on intake medical exam were significant negative predictors for improvement in the total SF-36 score (OR 0.23, 95% CI 0.08-0.80, P=0.021), with the effect driven largely by its impact on the physical component of SF-36 (OR 0.27, 95% CI 0.09-0.83, P=0.022). Conclusion: We demonstrated that a novel appointment-based CR program produced improvements in patient-reported health-related quality of life. Appointment-based CR could be a viable alternative for patients who prefer more scheduling flexibility, to optimize health status improvement and CVD outcomes.

scholarly journals Health related quality of life of survivors of trauma six months after discharge

2013 ◽  
Vol 69 (1) ◽  
Author(s):  
J. Schneiderman ◽  
H. Van Aswegen ◽  
P. Becker
Keyword(s):  
Quality Of Life ◽  
Physical Function ◽  
General Health ◽  
Mental Component Summary Score ◽  
Trauma Survivors ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

To investigate the health-related quality of life (HRQOL) of survivors of major trauma at six months following discharge, using two popular HRQOL tools. A cross-sectional study was done on adult trauma survivors in Johannesburg. Subjects completed the EQ-5D and SF-36 HRQOL questionnaires. Additional demographic and clinical data were collected. The majority of subjects reported some problems in usual activities and pain/discomfort as measured with the EQ-5D at six months. The mean EQ-5D VAS was 68 (±26.1). lowest scores were reported in the role physical (44.6 ± 41.6) and role emotional (44.1 ± 45.4) domains of the SF-36. mean SF-36 physical component summary (PCS) score (62.1 ± 27.8) was higher than mental component summary score (58.7 ±20.1). EQ-5D VAS was found to be moderately correlated with age (r=-0.4; p=0.05). A negative correlation was found between SF-36 physical function score and ICU length of stay (LOS), hospital LOS and age (r=-0.4 (p=0.03), -0.4 (p=0.03) and -0.6 (p=0.00) respectively). Statistical significance was observed in the correlation between age and SF-36 general health domain (r=-0.4; p=0.02) as well as age and PCS score (r=-0.5; p=0.01). Trauma survivors in Johannesburg experience limitations in specific emotional and physical domains of HRQOL at six months after discharge. Age was associated with the level of self-rated health as well as limitations in general health and physical function. ICU and hospital LOS were associated with limitations in physical function. There is a need for physical and psychological rehabilitation after discharge from trauma intensive care.

scholarly journals Impact of duration and treatment of arterial hypertension on health-related quality of life

Medicina ◽  
2009 ◽  
Vol 45 (5) ◽  
pp. 405 ◽  
Author(s):  
Vilma Raškelienė ◽  
Marija Babarskienė ◽  
Jūratė Macijauskienė ◽  
Arvydas Šeškevičius
Keyword(s):  
Quality Of Life ◽  
Arterial Hypertension ◽  
Physical Health ◽  
Physical Functioning ◽  
Health Related Quality ◽  
General Evaluation ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Arterial hypertension (AH) is one of the most important risk factors for development of ischemic heart disease; thus, control of AH and effective treatment are of great importance. Since arterial hypertension is commonly referred as asymptomatic condition, the question whether hypertensive condition is associated with the change of well-being and health-related quality of life is still debatable. The aim of the study. To evaluate the impact of duration and treatment of AH on health-related quality of life. Material and methods. The contingent of the study consisted of patients who arrived for a cardiologist’s consultation at the Clinic of Cardiology, Hospital of Kaunas University of Medicine. The patients were randomly selected for the study. The inclusion criteria were as follows: diagnosed arterial hypertension, diabetes mellitus, and the metabolic syndrome. Diagnosed ischemic heart disease (chronic and acute coronary syndromes and their complications) and severe concomitant diseases were exclusion criteria. A total of 101 patients (19 males and 82 females) met the inclusion criteria and consented to participate in the study. Their mean age was 58.03±5.63 years. The patients’ quality of life was evaluated using the Medical Outcomes Study short form 36-item questionnaire (SF-36 questionnaire), which comprises 36 questions grouped into eight domains. The questionnaire was filled in by the subjects independently. Other methods applied to the study were inquiry (for the evaluation of risk factors, lifestyle, and medical history), analysis of medical documents (cholesterol levels and glycemia in blood), and objective examination (height, weight, waist circumference, and arterial blood pressure). Results. The subjects with AH showed lower values compared to normotensive patients in the following domains: physical functioning (P=0.014), role limitations due to physical health (P=0.012), energy/vitality (P=0.016), and general health evaluation (P=0.023). We have not determined the differences in quality of life of the patients whose AH was regulated if compared to those patients without AH. The patients whose treatment of AH was not effective reported lower quality of life in the following SF-36 domains: physical functioning (P=0.003), role limitations due to physical health (P=0.003), general evaluation of health (P=0.017), energy/vitality (P=0.008), and emotional status (P=0.015), if compared to the patients without AH. Conclusions. Patients with AH reported lower quality of life in the following domains: physical functioning, role limitations due to physical health, energy/vitality, and general evaluation of health. Compared to patients without AH, the quality of life of the patients who had the effective treatment did not differ, whereas patients with ineffective treatment had the lower quality of life. Functioning is more statistically significantly limited due to physical health in patients with AH.

scholarly journals To assess the quality of life in patients with chronic kidney disease undergoing hemodialysis at a satellite clinic, comparing patients from a median low-income household with patients from median middle- and upper-income households: cross-sectional study

2020 ◽  
Author(s):  
UBIRACE FERNANDO ELIHIMAS JUNIOR ◽  
Marília Costa Aranha Forte ◽  
Alexandre Holanda Cavalcanti Pinto ◽  
Eduardo Eriko Tenório de França ◽  
Jamila Pinho Couto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Low Income ◽  
Physical Functioning ◽  
General Health ◽  
Positive Association ◽  
Hemodialysis Treatment ◽  
Sf 36

Abstract Background: Chronic kidney disease is a financial challenge for global public health due to rising costs, a poorer quality of life. Globally, there has been an increase in the number of diabetic, hypertensive and obese patients, with a tendency to rise as life expectancy increases. Objective: To assess the quality of life of patients with chronic kidney disease on hemodialysis at a satellite clinic in Recife, Northeast Brazil, and comparing low-income patients funded by the national healthcare system with middle- and higher-income patients funded by private health insurance. Methods: The Medical Outcomes Study Questionnaire Short Form 36 Health Survey (SF-36) was applied, together with a complementary interview with socio-demographic data for all patients at a conventional hemodialysis clinic. All patients were submitted to the same hemodialysis protocol, 4 hours and 10 minutes, high flow biocompatible membranes with high mass transfer coefficient and an adequacy of Kt/V ≥1.2. Results: The poorest quality of life scores with the SF-36 were related to physical functioning and pain. The best scores were attributed to mental health, social functioning, general health and vitality with no differences between the household incomes. There was a positive association between education, role-emotional and physical functioning. Longer hemodialysis treatment times demonstrated a positive association with aspects of general health. Patients who had undergone hemodialysis between one and five years presented better quality of life scores with the SF-36. Conclusions: Hemodialysis treatment negatively influences the quality of life of patients with chronic kidney disease. Education seems to help patients to better understand and accept treatment, by raising the scores of the physical functioning and role-physical. The first year of hemodialysis seems to exert a more negative influence on the quality of life. Among all patients, pain and physical aspects seem to be the critical points, regardless of social class or income.

scholarly journals Disparity in health-related quality of life between kidney transplant recipients and hemodialysis patients, and related implications for physical rehabilitation: A cross-sectional study

2021 ◽  
Author(s):  
Adnan L Sarhan ◽  
Raya H Jarareh ◽  
Mujahed Shraim
Keyword(s):  
Physical Functioning ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Transplant Recipients ◽  
Sectional Study ◽  
Kidney Transplant Recipients ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

Abstract Background Health related quality of life (HRQOL) is an important indicator of medical treatment and is a strong predictor of disability and mortality. The literature has shown mixed evidence about whether kidney transplantation improves HRQOL compared with other renal replacement modalities. The aim of this study was to compare the HRQOL in kidney transplant recipients (KTRs) and hemodialysis (HD) patients. Methods A cross-sectional study of 100 KTRs and 272 HD patients from two central kidney units in West Bank, Palestine. The HRQOL was assessed using the Short Form-36 Health Survey. Multivariable linear regression was used to estimate differences in mean HRQOL scores between KTRs and HD patients. Results After accounting for sociodemographic variables, KTRs had higher clinically important differences than HD patients in HRQOL mean scores in role-physical, bodily pain, general health, vitality, social functioning, role-emotional, mental health, physical and mental component summaries ranging from 15.5 points for social functioning (95% CI 10.1, 20.7) to 34.3 points for general health (95% CI 28.7, 39.9). However, unexpectedly, KTRs had significantly lower HRQOL physical functioning than HD patients by 24.5 points (95% CI 18.7, 29.9). Conclusions Kidney transplantation is associated with important improvements in most aspects of HRQOL but also with noticeably poor physical functioning. HRQOL among KTRs should be routinely measured and closely monitored in clinical settings. KTRs should be encouraged to participate in individually tailored physical exercise programs. Identification and elimination of barriers to physical functioning may improve HRQOL and prevent premature mortality among KTRs.

scholarly journals Analysis of Factors Affecting Employment Status of Kidney Transplant Recipients in Selected European Union Member States

2021 ◽  
Vol 18 (19) ◽  
pp. 10284
Author(s):  
Elzbieta Wlodarczyk ◽  
Ondřej Viklický ◽  
Klemens Budde ◽  
Marie Kolářová ◽  
Leon Bergfeld ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Kidney Transplantation ◽  
Renal Transplantation ◽  
Renal Transplant ◽  
Employment Status ◽  
Professional Activity ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Sf 36

Despite an increasing quality of life after renal transplantation, the number of recipients undertaking paid professional work remains relatively low. Employment after kidney transplantation became a new important marker of clinically significant health recovery. Furthermore, for social and economic reasons, returning to work and participation in social life may be considered as an objective parameter that demonstrate the effectiveness of transplantation. The objectives of the following study were to evaluate the factors that determine resuming paid work after renal transplantation, to assess a patient’s decision about returning to professional activity by comparative analysis of renal transplant recipients from Poland, Czech Republic and Germany, and to identify groups of patients exposed to professional exclusion in those EU countries. Five hundred renal transplant recipients from three EU countries were included into the study. The two main research methods used in the study were the SF-36 questionnaire, constructed and validated to assess the quality of life after kidney transplantation and a questionnaire constructed for the purposes of this study. Multifactorial analysis identified several risk factors associated with professional exclusions after kidney transplantation, namely young or advanced age, female gender, lack of education, place of residence in rural areas, long period of illness, and lack of occupational activity before transplantation. Despite the high standards of social care and rehabilitation support, patients in Germany failed to take up professional activity after kidney transplantation in more cases than those in Poland and Czech Republic. Surprisingly, the objective function of the kidney (creatinine level) and the multidimensional assessment of quality of life (SF-36 survey) did not have a significant association with the employment status after renal transplantation.

Abstract 2090: Health Related Quality of Life Outcomes of Therapeutic Life Style Modification Program for Women with Metabolic Syndrome

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Eui Geum Oh ◽  
Soo Hyun Kim ◽  
So Yeon Bang ◽  
Sa Saeng Hyun ◽  
Yong Kwan Jeon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
General Health ◽  
Control Group ◽  
Health Related Quality ◽  
Point Change ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Background: The metabolic syndrome (MetS), with associated increased CHD risk, is highly prevalent among postmenopausal women in Korea. Although therapeutic lifestyle modification (TLM) has been recommended as a cornerstone therapy, studies investigating the effects of TLM on health related quality of life (HRQOL) are limited. Purpose : This study was to evaluate HRQOL outcomes of a six-month TLM in Korean women with Mets. Methods: A randomized controlled design was used. Fifty four women (mean age of 63.2 y) with Mets were recruited from community health centers and randomly assigned to the intervention (N=31) or control (N=23) groups. The subjects in the intervention group participated in a supervised weekly TLM session for six months. The TLM program was consisted of health monitoring, education, aerobic exercise (40-min/session, 200 Kcal/day), and a low calorie diet with low carbohydrate (≈1300Kcal/d). Those in the control group received a booklet about MetS and were instructed to maintain their usual diet and activities. HRQOL was measured using the MOS SF-36 at before, during (month 3), completion (month 6), and after completion of the TLM program (month 12). Mixed-model repeated measures ANCOVA was used to evaluate HRQOL outcomes. Results : There were significant group by time interactions for general health ( P = .043) and vitality ( P = .012). Both general health (mean 23-point change) and vitality scores (mean 16-point change) greatly improved in the treatment group over 6 months of TLM, compared with control group. However, the improvement of the general health and vitality in the experimental group was not sustained at month 12. There were significant treatment main effects (all P < .05) for the remaining SF-36 subscale scores. Conclusion : A systematic TLM program may be effective strategy for improving HRQOL in postmenopausal women with MetS.

MO951ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN A GREEK COHORT OF KIDNEY TRANSPLANT RECIPIENTS WITH THE KIDNEY TRANSPLANT QUESTIONNAIRE (KTQ-25)

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Vasileios Koutlas ◽  
Eirini Tzalavra ◽  
Vasileios Tatsis ◽  
Anila Duni ◽  
Haralambos Pappas ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Physical Symptoms ◽  
Health Related Quality ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Male Sex

Abstract Background and Aims Kidney transplantation is recognized as the treatment of choice for patients with End Stage Kidney Disease (ESKD). Improvement in short term patient and graft survival of kidney transplant recipients (KTRs), has shifted interest to the long-term outcomes and Health-Related Quality of Life (HRQoL) estimation is closely related. Thus, reliable evaluation of HRQoL with disease specific questionnaires is of great importance. The aim of this study was to assess the HRQoL in adult KTRs of our Transplant Unit with Kidney Transplant Questionnaire 25 (KTQ-25) and the 36-item Short Form Health Survey (SF-36). Method The Greek version of the recently translated and adapted by our team disease specific instrument KTQ-25 and the Greek SF-36 were administered in KTRs during their routine visit in the transplant outpatient clinic. Patients who met the eligibility criteria (time since transplant≥1 year, aged≥18 year old, functioning transplant) were included after providing written informed consent. Results A total of 84 KTRs (59 males; mean age 53.45±10.72; mean e-GFR 47.69±15.07; average time since transplantation 55.68±48.26 months) completed the two questionnaires. The scores in each dimension of KTQ-25 were: Physical Symptoms 3.98±1.60, Fatigue 5.30±1.36, Uncertainty/Fear 5.16±1.33, Appearance 6.31±0.94, Emotions 5.03±1.07 and Total Score 5.20±0.87. The mean SF-36 Physical Component Score (PCS) and Mental Component Score (MCS) scores were 47.98±8.70 and 46.94±9.70 respectively. Fatigue (p=0.009), Uncertainty/Fear (p=0.008) and Total Score (p&lt;0.001) were better in male sex. Physical Symptoms (p=0.013) was better in KTRs with children than those with no children. There was positive correlation of e-GFR with Fatigue (p 0.002), Uncertainty/Fear (p=0.034) and Total Score (p=0.017). Hgb was positive correlated with Fatigue (p&lt;0.001), Uncertainty/Fear (p&lt;0.001), Emotions (p=0.031) and Total Score (p&lt;0.001). KTRs who were receiving EPO for anemia had worse scores in all dimension of KTQ-25 (Physical Symptoms p=0.001; Fatigue p=0.001; Uncertainty/Fear p=0.021; Emotions p=0.010; Total Score p=0.002) except Appearance. Appearance was negative correlated with Weight (p=0.001) and BMI (p=0.001). Total number of daily taken pills was also significantly negative correlated with Fatigue (p=0.006) and Total Score (p=0.007). No differences found between different immunosuppressive therapies. Conclusion In our cohort of Greek adults KTRs maximum KTQ-25 score was obtained in Appearance dimension and the minimum in Physical Symptoms dimension. Fatigue, Uncertainty/Fear dimensions and Total Score were better for male sex and for KTRs with higher e-GFR and Hgb levels. Physical Symptoms score was better only for KTRs having children. Overweight and high BMI negatively affected A dimension. This is the first study to use a specific-disease tool for evaluating HRQoL in Greek KTRs and among our significant results is that better graft function is significantly correlated with better HRQoL.

scholarly journals 05 Long-term health-related quality of life in adult survivors of pediatric intracranial germ cell tumour

2018 ◽  
Vol 45 (S3) ◽  
pp. S1-S1
Author(s):  
Andrea Lo ◽  
Normand Laperriere ◽  
David Hodgson ◽  
Karen Goddard
Keyword(s):  
Germ Cell ◽  
Social Functioning ◽  
General Health ◽  
Germ Cell Tumors ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

PURPOSE: To investigate health-related quality of life (HRQOL ) in survivors of intracranial germ cell tumors (IGCT). METHODS: Survivors of IGCT were invited to complete the 36-Item Short Form Survey Instrument (SF-36). The SF-36 is scored from 0-100, with a higher number representing a more favorable HRQOL. RESULTS: The study cohort consisted of 12 survivors of IGCT, 6 males and 6 females. Median age was 13 years at diagnosis, and 26 years at time of study. Median follow-up was 11 years. Five patients had germinomas, and 7 had non-germinomatous germ cell tumors. All 12 patients received radiation therapy (RT), 10 to the craniospinal axis, 1 to the whole ventricles and 1 to the tumor bed alone. Nine patients received chemotherapy. Mean SF-36 scores were 67.9 (standard deviation [SD] 33.2) for physical functioning, 58.3 (SD 37.4) for role limitations due to physical health, 77.8 (SD 32.8) for role limitations due to emotional problems, 43.1 (SD 18.4) for vitality, 74.3 (SD 15.3) for mental health; 62.5 (SD 32.0) for social functioning, 74.2 (SD 33.4) for pain, and 57.1 (SD 24.0) for general health; mean scores were >1 SD lower than that of Canadian normative data for vitality, social functioning and general health. Physical component score was 43.6 (SD 13.9) and mental component score was 47.6 (SD 11.2), normalized to a US population with mean of 50 and SD of 10. CONCLUSIONS: Long-term HRQOL for survivors of IGCT is lower than that of the overall population, particularly in vitality, social functioning and general health.

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