Thermography and colour Doppler ultrasound: a potential complementary diagnostic tool in evaluation of rheumatoid arthritis in the knee region

2020 ◽  
Vol 65 (3) ◽  
pp. 289-299
Author(s):  
Snekhalatha Umapathy ◽  
Rajalakshmi Thulasi ◽  
Nilkanth Gupta ◽  
Suma Sivanadhan

AbstractThe aim and objectives of this study were as follows: (i) to perform automated segmentation of knee thermal image using the regional isotherm-based segmentation (RIBS) algorithm and segmentation of ultrasound image using the image J software; (ii) to implement the RIBS algorithm using computer-aided diagnostic (CAD) tools for classification of rheumatoid arthritis (RA) patients and normal subjects based on feature extraction values; and (iii) to correlate the extracted thermal imaging features and colour Doppler ultrasound (CDUS) features in the knee region with the biochemical parameters in RA patients. Thermal image analysis based on skin temperature measurement and thermal image segmentation was performed using the RIBS algorithm in the knee region of RA patients and controls. There was an increase in the average skin temperature of 5.94% observed in RA patients compared to normal. CDUS parameters such as perfusion, effusion and colour fraction for the RA patients were found to be 1.2 ± 0.5, 1.8 ± 0.2 and 0.052 ± 0.002, respectively. CDUS measurements were performed and analysed using the image J software. Biochemical parameters such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) showed significant positive correlation with the thermal imaging parameters. The CDUS parameters such as effusion, perfusion and colour fraction correlated significantly with the clinical and functional assessment score. According to the results of this study, both infrared (IR) thermal imaging and CDUS offer better diagnostic potential in detecting early-stage RA. Therefore, the developed CAD model using thermal imaging could be used as a pre-screening tool to diagnose RA in the knee region.

1996 ◽  
Vol 75 (02) ◽  
pp. 242-245 ◽  
Author(s):  
Marie Magnusson ◽  
Bengt I Eriksson ◽  
Peter Kãlebo ◽  
Ramon Sivertsson

SummaryPatients undergoing orthopedic surgery are at high risk of developing deep vein thrombosis. One hundred and thirty-eight consecutive patients undergoing total hip replacement or hip fracture surgery were included in this study. They were surveilled with colour Doppler ultrasound (CDU) and bilateral ascending contrast phlebography. The prevalence of proximal and distal DVT in this study was 5.8% and 20.3% respectively.CDU has a satisfactory sensitivity in patients with symptomatic deep vein thrombosis, especially in the proximal region. These results could not be confirmed in the present study of asymptomatic patients. The sensitivity was 62.5% (95% confidence interval: C.I. 24-91%) and the specificity 99.6% (C.I. 98-100%) for proximal DVT; 53.6% (C.I. 34-73%) and 98% (C.I. 96-99%) respectively for distal thrombi. The overall sensitivity was 58.1% (C.I. 39-75%) and the specificity 98% (C.I. 96-99%). The positive predictive value was 83.3% (C.I. 36-99%) and 75% (C.I. 51-91%) for proximal and distal DVT respectively. The negative predictive value was 98.9% (C.I. 98-100%) and 94.9% (C.I. 92-98%) for proximal and distal DVT respectively. The results of this study showed that even with a highly specialised and experienced investigator the sensitivity of CDU was too low to make it suitable for screening purposes in a high risk surgical population.


1995 ◽  
Vol 50 (9) ◽  
pp. 618-622 ◽  
Author(s):  
G.M. Baxter ◽  
H. Ireland ◽  
J.G. Moss ◽  
P.N. Harden ◽  
B.J.R. Junor ◽  
...  

2004 ◽  
Vol 34 (8) ◽  
pp. 614-619 ◽  
Author(s):  
Jos A. M. Bramer ◽  
Feikje M. Gubler ◽  
Mario Maas ◽  
Hans Bras ◽  
Jan de Kraker ◽  
...  

1996 ◽  
Vol 69 (825) ◽  
pp. 810-815 ◽  
Author(s):  
G M Baxter ◽  
F Aitchison ◽  
D Sheppard ◽  
J G Moss ◽  
M J McLeod ◽  
...  

1996 ◽  
Vol 11 (10) ◽  
pp. 2333-2333
Author(s):  
A. Tekay ◽  
H. Martikainen ◽  
P Jouppila

2013 ◽  
Vol 3 (4) ◽  
pp. 304 ◽  
Author(s):  
Rei K. Chiou ◽  
Himanshu Aggarwal ◽  
Christopher R. Chiou ◽  
Fleur Broughton ◽  
Susan Liu

Background: Information in the literature on the hemodynamic characteristicsof priapism, especially after therapeutic intervention, isvery limited. We analyzed our colour Doppler ultrasound (CDU)studies performed for patients with various durations of priapismbefore and after therapeutic intervention.Methods: We reviewed 52 CDU studies for 24 patients with priapismbefore and after treatment for the period 1997–2007. Theduration of priapism ranged from 4 hours to 8 days. We performed17 CDU studies in 8 patients who presented with a duration ofpriapism of 7 hours or less, 9 studies in 4 patients who presentedwith duration of priapism of more than 20 hours, 23 studies in11 patients referred to us after they had failed prior therapeuticintervention at other institutions and 3 studies in 1 patient withpriapism related to perineal trauma.Results: Among the 8 patients who presented with a duration ofpriapism of 7 hours or less, CDU studies on presentation showeddetectible cavernosal arterial flow in all except 1 study. Amongthe 4 patients who presented with a duration of more than 20 hours,the studies showed no detectible cavernosal arterial blood flow.We repeated CDU studies after therapeutic intervention, and theyshowed restoration of cavernosal arterial flow with relief of venoocclusivestatus. Among the 11 patients in whom prior treatmentsfailed before they were referred to us, CDU studies performed onpresentation showed no detectible cavernosal arterial flow in 10of the 11 patients. We performed 12 CDU studies in 8 patientsafter placing a penile cavernosa-dorsal vein (CD) shunt. Weobserved the presence of blood flow in the CD shunt, indicatingits patency in all 8 patients. Some patients showed high cavernosalarterial flow (peak systolic velocity [PSV] up to 27.6 cm/s) aftersurgery. These patients appeared to have residual priapism of primarilyarteriogenic status that improved after observation.Conclusion: After therapeutic intervention, CDU study is useful toassess the relief of arteriogenic and veno-occlusive status and thedecision for further treatment.Contexte : La littérature offre très peu de renseignements sur lescaractéristiques hémodynamiques du priapisme, en particulieraprès une intervention thérapeutique. Nous avons analysé les donnéesprovenant d’examens par échographie Doppler en couleurs(ÉDC) menés avant et après une intervention thérapeutique chezdes patients atteints de priapisme de durée variable.Méthodes : Nous avons passé en revue les données de 52 examenspar échographie Doppler en couleurs effectués avant et après letraitement de 24 patients atteints de priapisme entre 1997 et 2007.La durée du priapisme variait entre 4 heures et 8 jours. Dix-septÉDC ont été effectuées chez 8 patients ayant présenté un priapismed’une durée maximale de 7 heures; 9 ÉDC ont été effectuées chez4 patients ayant présenté un priapisme d’une durée de plus de20 heures. Finalement, 23 ÉDC ont été effectuées chez 11 patientsqui nous avaient été dirigés en raison de l’échec de l’interventionthérapeutique antérieure dans d’autres établissements. Trois ÉDCont été menées chez un patient atteint d’un priapisme relié à untraumatisme périnéal.Résultats : Chez les 8 patients dont le priapisme avait eu une duréemaximale de 7 heures, les ÉDC ont montré au départ un débit sanguinperceptible dans l’artère caverneuse dans tous les cas sauf un. Surles 4 patients dont le priapisme avait duré plus de 20 heures, les examenspar ÉDC n’ont montré aucun débit sanguin dans l’artère caverneuseau départ. Les ÉDC ont été répétées après l’interventionthérapeutique et ont permis d’observer un retour du débit sanguindans l’artère caverneuse avec soulagement de l’occlusion veineuse.Chez les 11 patients qui n’avaient pas répondu aux traitementsantérieurs avant de nous consulter, les ÉDC effectuées au départ n’ontmontré aucun débit sanguin perceptible dans l’artère caverneusedans 10 cas. Nous avons effectué 12 ÉDC chez 8 patients après unedérivation veineuse dorso-caverneuse et avons observé la présenced’un débit sanguin dans la dérivation, montrant sa perméabilité chezles 8 patients. Chez certains patients, on a noté un débit sanguinélevé dans l’artère caverneuse (vitesse systolique maximale de27,6 cm/sec) après la chirurgie. Ces patients semblaient présenter unpriapisme résiduel artériogène primaire qui s’est résorbé par la suite.Conclusion : Après une intervention thérapeutique, les examens parÉDC permettent d’évaluer le soulagement des troubles artériogèneset/ou veino-occlusifs et d’orienter le traitement subséquent.


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