scholarly journals Biocompatibility of magnetic iron oxide nanoparticles for biomedical applications

2019 ◽  
Vol 5 (1) ◽  
pp. 573-576
Author(s):  
Claudia Matschegewski ◽  
Anja Kowalski ◽  
Knut Müller ◽  
Henrik Teller ◽  
Niels Grabow ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Biomedical Applications ◽  
Drug Carriers ◽  
Iron Oxide Nanoparticle ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Hyperthermia Treatment ◽  
Magnetic Iron Oxide ◽  
In Vitro Biocompatibility ◽  
Biological Performance

AbstractMagnetic nanoparticles are highly promising for the usage in various biomedical applications including magnetic particle imaging (MPI), cancer hyperthermia treatment or as drug carriers. The present study aims at assessing in vitro biocompatibility of two commercially available magnetic iron oxide nanoparticle formulations: dextran-based magnetic nanoparticle synomag-D and bionized nanoferrite BNF-starch. Biological performance of both nanoparticle formulations were studied in human endothelial cells by analyzing cell viability and nanoparticle internalization in order to judge their suitability as theranostics.

Controlling the Size and Shape of Uniform Magnetic Iron Oxide Nanoparticles for Biomedical Applications

2018 ◽  
pp. 3-24
Author(s):  
Helena Gavilán ◽  
Maria Eugênia Fortes Brollo ◽  
Lucía Gutiérrez ◽  
Sabino Veintemillas-Verdaguer ◽  
María del Puerto Morales
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide ◽  
Size And Shape

Influence of Sargassum crassifolium Extract on the Absorption of Magnetic Iron Oxide Nanoparticle via Green Synthesis Route

2019 ◽  
Vol 803 ◽  
pp. 382-386 ◽  
Author(s):  
Marco Laurence M. Budlayan ◽  
Arnold C. Alguno ◽  
Rey Y. Capangpangan
Keyword(s):  
Iron Oxide ◽  
Green Synthesis ◽  
Average Diameter ◽  
Seaweed Extract ◽  
Iron Oxide Nanoparticle ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Environmental Application ◽  
Magnetic Iron Oxide ◽  
Synthesis Route ◽  
20 Nm

This work reported the influence of seaweed (Sargassumcrassifolium) extract on the absorption of magnetic iron oxide nanoparticles (MIONPs) via green synthesis route. The seaweed extract acted as reducing and capping agent. Ultraviolet-visible (UV-Vis) spectra revealed the presence of sharp peaks at around 366 nm to 371 nm which corresponds to the absorption spectra of MIONPs. The absorption peaks corresponding to MIONPs was significantly affected by the varying amount of seaweed extract. On the other hand, Fourier Transform-Infrared (FTIR) spectra revealed the presence of the vibration mode around 532 cm-1 to 551 cm-1 which corresponds to Fe-O bands suggesting the successful formation of MIONPs. Thermogravimetric (TGA) spectra showed that the produced MIONPs stabilizes at 400 °C. The synthesized MIONPs are spherical in shape with an estimated average diameter of 20 nm as revealed by the Field Emission Scanning Electron Microscopy (FESEM). Finally, the produced MIONPs exhibit magnetic property via attraction with an external magnet. This straight forward green synthesis of MIONPs can be a good route for possible industrial and environmental application.

Characterization of Cell Association and Heat Treatment Using Iron Oxide Magnetic Nanoparticles

2007 ◽  
Author(s):  
Venkat S. Kalambur ◽  
Ellen Longmire ◽  
John C. Bischof
Keyword(s):  
Iron Oxide ◽  
Cell Sorting ◽  
Biomedical Applications ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Non Invasive ◽  
Cell Association ◽  
Iron Oxide Magnetic Nanoparticles ◽  
Magnetic Resonance Imaging Mri

Magnetic iron oxide nanoparticles (NPs) have intrinsic advantages over other NPs for various biomedical applications. These advantages include visualization under Magnetic Resonance Imaging (MRI), heating with Radiofrequency (RF), and movement in a magnetic field. There are now numerous efforts to expand the applications of these particles for non-invasive drug and adjuvant delivery, cellular imaging and in vitro cell sorting and purification. In the present study, we describe methods to (i) assess and quantify NP cell association (ii) facilitate NP heat destruction of cells after association with RF and laser. First, we show that (i) the cell association of iron oxide NPs is dependent on the surface coating (surfactant greater than dextran), time, cell-type and extracellular NP concentrations (saturation with concentration and time). Furthermore, the association fits a simple enzyme Michealis-Menten model. Second, (ii) improved heat destruction of cells can be achieved after laser irradiation compared to traditional RF treatment for similar NP associations. These results and assays show promise for cell sorting and purification applications.

COLLOIDAL STABILITY AND MONODISPERSIBLE MAGNETIC IRON OXIDE NANOPARTICLES IN BIOTECHNOLOGY APPLICATION

2013 ◽  
Vol 12 (06) ◽  
pp. 1330002 ◽  
Author(s):  
K. SHAMILI ◽  
E. M. RAJESH ◽  
R. RAJENDRAN ◽  
S. R. MADHAN SHANKAR ◽  
M. ELANGO ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Colloidal Stability ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Fluid Hyperthermia ◽  
Magnetic Iron Oxide ◽  
Magnetic Resonance Imaging Mri ◽  
Co Precipitation

Magnetic iron oxide nanoparticles are promising material for various biological applications. In the recent decades, magnetic iron oxide nanoparticles (MNPs) have great attention in biomedical applications such as drug delivery, magnetic resonance imaging (MRI) and magnetic fluid hyperthermia (MFH). This review focuses on the colloidal stability and monodispersity properties of MNPs, which pay more attention toward biomedical applications. The simplest and the most promising method for the synthesis of MNPs is co-precipitation. The biocompatible MNPs are more interested in MRI application. This review also apportions synthesis, characterization and applications of MNP in biological and biomedical as theranostics and imaging.

Pharmaceutical and Biomedical Applications of Magnetic Iron-Oxide Nanoparticles

2017 ◽  
pp. 77-99
Author(s):  
Kelly J. Dussán ◽  
Ellen C. Giese ◽  
Gustavo N. A. Vieira ◽  
Lionete N. Lima ◽  
Debora D. V. Silva
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide

Magnetic iron oxide nanoparticles for biomedical applications

2010 ◽  
Vol 2 (3) ◽  
pp. 427-449 ◽  
Author(s):  
Sophie Laurent ◽  
Jean-Luc Bridot ◽  
Luce Vander Elst ◽  
Robert N Muller
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Iron Oxide
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